New invention allows for cost-effective and early serial tests through logarithmic procedure

Due to PCR direct tests during the procedure which blocks cross-contamination, latency periods can be avoided

Darmstadt, Juli 01, 2014 – The new logarithmic procedure allows for expensive linear tests to be avoided in the future. Thanks to the invention by Darmstadt computer scientist Thomas Taeger, herds of animals, drinking water, fungal spores and other liquid or gaseous samples can be tested cost-efficiently and securely by means of a logarithmic procedure. Even the latency period which often lasts several weeks may be avoided if there are direct tests which detect DNA directly instead of antibodies.

Present serial tests, for example of herds of animals, often work with linear complexity even in case of a low share of positive samples, cause high device effort and a risk of cross-contamination due to pipetting, rarely use direct test methods, such as PCR, and therefore have long latency periods.
"If linear complexity is to be avoided for serial investigations you cannot get around composite samples and amplification. However, there is all the more the risk of cross-contamination due to aerosol formation," Thomas Taeger describes the problem which can now be solved thanks to his new procedure. The patent specification available since May 2014 can be found under: http://www.disoa.de/img/LogScr-DE-Thomas.Taeger-2014-05-08-600.pdf

Although Thomas Taeger is actually a computer scientist, he was able to work without regulation electronics and handling devices and develop a tree-like array of composite sample chambers which allows for the samples to be passed on in a clocked way by multiple tilting via suction lifters towards the root node. Synchronously to the samples, oil to cover and seal the lines is also fed in through separate oil lines. Also pressure compensation between the composite sample chambers is done in closed systems to avoid cross-contamination. Thus, there are three independent line systems: sample line and oil line towards the root and pressure compensation line in the opposite direction. "Retrospectively, the invention seems to be as simple as the gasoline engine – using solely 'middle school physics'," says Thomas Taeger with a chuckle. The tree structure can also be implemented in cost-effective plastic injection molding. By PCT application, national patent licenses are still globally possible.

"The invention can be reasonably used in all cases where 'few needles in a haystack' are to be found. In these cases, it generates the best logarithmic complexity. With the new test procedure, the costs do not incur for each single sample as in the past but only for few composite samples. Direct tests obtain immediate test results and render antibody tests with a latency period of several months unnecessary. For BSE serial tests, for example, it is thus no longer required to club entire herds of cattle," Thomas Taeger describes one of the outstanding advantages of his new test procedure.

The core characteristics are:
- serial tests of liquid or gaseous samples
- logarithmic complexity through tree structure
- minimal latency period due to direct tests (PCR)
- blocks cross-contamination due to covering oil and pressure compensation in closed systems
- not bound to a specific test method
- secure: does not provoke false-negative results
- without regulation electronics
- without handling devices
- works almost automatically (simple tilting)
- can be implemented in the simplest of infrastructures
- cost-effective plastic injection molding chambers
- same injection molding positive model for all levels
- little hazardous waste
- cascadable
- PCT application

Contact:
Thomas Taeger
Jahnstr. 53
64285 Darmstadt, Germany
Cell phone: +49 (0)160-4448842
Email: taeger@classic-and-class.com

About the inventor:
Computer scientist Thomas Taeger is not only an inventor but has been a full-time freelance J2EE and SOA architect since 2004 with a focus on dependency modeling (UML and data modeling), service design and design patterns. Since 1995, Java has been his activity emphasis. Since 1982, the computer scientist had been working in structured programming (among others Pascal and Assembler) for technical process data processing.
Moreover, Thomas Taeger has been conducting trainings, reviews and coachings for many years. The inventor has several established certificates, while OOA, OOD and of course modeling with UML-2 and structured ER models (SERM) are his daily business. Current and also older technical projects can be found under: http://www.classic-and-class.com/Taeger-Profil.pdf. For further information on Thomas Taeger, please visit: http://www.classic-and-class.com.

This release was published on openPR.