IBD (Ulcerative Colitis and Crohn's Disease) Treatment Market Analysis and Opportunity Assessment up to 2022-2031

IBD (Ulcerative Colitis & Crohn's Disease) Treatment Market Outlook 2031

The global IBD (ulcerative colitis & Cohn's disease) treatment market was valued at US$ 17.3 Bn in 2021

The global market is projected to grow at a CAGR of 6.8% from 2022 to 2031

The global IBD (ulcerative colitis & Cohn's disease) treatment market is anticipated to reach more than US$ 34.22 Bn by 2031

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IBD (Ulcerative Colitis & Crohn's Disease) Treatment Market Introduction

Rise in prevalence of inflammatory bowel disease (IBD) across the globe is driving the global IBD (Ulcerative Colitis & Crohn's Disease) treatment market. IBD is a group of gastrointestinal inflammatory diseases that primarily comprises ulcerative colitis and Crohn's disease. Inflammatory bowel diseases cause long-term chronic inflammation of the gastrointestinal (GI) tract without any known cause. Ulcerative colitis disease mostly affects the inner lining of large intestines and causes inflammation and sores in the colon. Ulcerative colitis is a more commonly observed disease than Crohn's disease. It can affect any part of the gastrointestinal tract, starting from the mouth to the small intestine and anus. Common symptoms of IBD include chronic pain and cramps in the abdomen, persistent diarrhea, occasional rectal bleeding, and fever. The exact cause of inflammatory bowel disease is not well understood, and high prevalence and incidence rates of these diseases have been observed in developed countries.

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Innovations in product development, approval of drugs, and rising inclination toward the use of biologic and biosimilar drugs are the factors driving the global IBD treatment market. Growth in sales of IBD drugs through online, retail, and hospital pharmacies is helping companies generate more revenues. For instance, in December 2019, the FDA approved two biosimilars - adalimumab and infliximab - for the treatment of Ulcerative Colitis. Biopharmaceutical companies have made significant investments in R&D activities. Large numbers of pipeline products are in different stages of clinical approvals, which are likely to commercialize during the forecast period. Furthermore, high prevalence and incidence of IBD in countries in the West is anticipated to augment the global market. According to a report, around 2.5 million people in the U.S. suffered from inflammatory bowel disease in 2020. The prevalence of IBD among the U.S. population is expected to rise to around 3.5 million by 2030. Similarly, data suggests that the incidence and prevalence of inflammatory bowel diseases [IBD] is still increasing in Europe; around 0.2% of the population of Europe suffered from IBD in 2020.

COVID-19 Impact on IBD (Ulcerative Colitis & Crohn's Disease) Treatment Market

The outbreak of COVID-19 has had a negative effect on the global IBD treatment market, as many governments of affected countries gave instructions for the postponement of non-essential surgeries and patient visits. Lockdowns in several countries, travel restrictions, and closure of the diagnostic centers led to a substantial decline in overall diagnostic procedures and treatments. According to two research letters published in JAMA Internal Medicine, there were 6,411 non-COVID-19 hospitalizations, including pediatric inflammatory bowel diseases, in 2019. This data is based on admissions to four hospitals in New York. However, the total admission in 2020 was 3,657 for the same conditions, while the overall decline of non-patients was around 40%. Players operating in the market witnessed a decline in revenue during the financial year 2020. For instance, Pfizer, Inc. registered a decline of -3.5% in revenue generated from its inflammation & immunology segment in 2020. Nevertheless, the market has seen a recovery from COVID-19 impact due to the easing of restrictions by various governments across the globe. Demand for drugs increased in 2021 due to the rise in diagnosis rate of diseases. Leading companies in the market reported an increase in revenue during 2021. Hence, the future IBD treatment market is anticipated to witness recovery at pre-pandemic levels.

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Superior Efficacy, Safety, and Better Therapeutic Outcomes Augmenting Adoption of TNF Inhibitors

The TNF inhibitors segment is projected to lead the global IBD (ulcerative colitis and Crohn's disease) treatment market during the forecast period. The segment's large market share can be ascribed to superior efficacy and safety of drugs in this class in the treatment of IBD, increase in adoption of biologics and biosimilars in countries in the West such as the U.K., France, Germany, and the U.S., and high cost of these drugs. Furthermore, rise in adoption of biologic drugs for the treatment of IBD and high clinical R&D budgets contributed to the TNF inhibitors segment's large share in 2021. TNF inhibitors are used as the second line of treatment when other medications do not work effectively to relieve symptoms of IBD. High adoption of TNF inhibitors owing to promising therapeutic results for the management of IBD, high per capita health care expenditure, and increase in number of hospitalizations can be ascribed to the TNF inhibitors segment's significant market share in 2021.

High Prevalence and Incidence of Ulcerative Colitis to Drive Demand for IBD Treatment

The ulcerative colitis segment accounted for the largest share of the global market in 2021. The trend is expected to continue during the forecast period. High prevalence and incidence of ulcerative colitis in Europe and North America, increase in awareness about the disease, and rise in number of hospitalization cases of ulcerative colitis are the key factors driving the ulcerative colitis segment. An article published on NCBI (2020) stated that ulcerative colitis has an incidence of 9 to 20 cases per 100,000 per year. Its prevalence is 156 to 291 cases per 100,000 per year in North America and Europe. Similarly, in Canada, more than 104,000 people are living with ulcerative colitis and nearly 4,500 cases of ulcerative colitis are diagnosed every year. Furthermore, a recent report suggests that 600,000 to 900,000 people in the U.S. have ulcerative colitis.

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Availability of Wide Range of Drugs for IBD Propelling Retail Pharmacies Segment

The retail pharmacies segment dominated the global market in terms of market share in 2021 due to the rise in sale of biologic drugs through retail pharmacy chains in the U.S. Biologic drugs accounted for major share of the IBD treatment market in the U.S. in 2021. Easy availability of drugs such as corticosteroids, Aminosalicylates, and biologics at retail pharmacy stores and usage of these drugs, except biologics, as the first line of treatment is propelling the retail pharmacies segment. Moreover, retail pharmacies are considered the first point of contact for self-medication. In 2019, India had more than 800,000 pharmacies; retail pharmacies are still the dominant medical distribution channel. Hence, presence of a large existing base of retail pharmacy stores in countries such as India, China, the U.S., and Canada is likely to augment the retail pharmacies segment during the forecast period.

Regional Outlook of Global IBD (Ulcerative Colitis & Crohn's Disease) Treatment Market

North America dominated the global IBD (ulcerative colitis and Crohn's disease) treatment market in 2021. It is projected to gain major market share by the end of 2031. The region's dominance of the global market can be ascribed to high prevalence and increase in incidence of ulcerative colitis and Crohn's disease in the U.S. and Canada, well-established healthcare infrastructure, and high risk of lifestyle-related factors. Additionally, strong product pipeline of key players is projected to drive the global IBD (ulcerative colitis and Crohn's disease) treatment market in the region.

Asia Pacific is projected to be the fastest growing market for IBD (ulcerative colitis and Crohn's disease) treatment during the forecast period. Japan dominated the IBD treatment market in the region in 2021. The IBD (ulcerative colitis and Crohn's disease) treatment market in China is anticipated to grow at a high CAGR during the forecast period. The IBD (ulcerative colitis and Crohn's disease) treatment market in Latin America and Middle East & Africa is likely to expand at a decent CAGR during the forecast period due to the increase in IBD patient pool and rise in focus of manufacturers on the development of novel therapeutics.

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Key Developments in Global IBD (Ulcerative Colitis & Crohn's Disease) Treatment Market

In May 2021, Bristol Myers Squibb announced that the Food and Drug Administration (FDA) approved Zeposia (ozanimod) for the treatment of moderate to severe active ulcerative colitis in adults
In September 2019, Janssen Biotech, Inc.'s product, STELARA, was approved for the treatment of moderate to severe active ulcerative colitis in the European Union
In April 2019, Salix Pharmaceuticals entered into an exclusive license agreement with Mitsubishi Tanabe Pharma to commercialize and develop late stage investigational S1P modulator for the treatment of inflammatory bowel disease
In October 2018, Allergan launched a personalized study approach for clinical research programs in inflammatory bowel disease. These programs would evaluate the efficacy and safety of brazikumab and the potential correlation between biomarkers and the patient outcomes with brazikumab.

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Each of these players has been profiled in the IBD (ulcerative colitis & Crohn's disease) treatment market report based on parameters such as company overview, financial overview, business strategies, product portfolio, business segments, and recent developments.

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