Alpha-Mannosidosis Market Is Expected To Grow During the Study Period (2019-2032), DelveInsight | Key Companies- Chiesi, SmartPharma, and Several Others

"The increase in Alpha Mannosidosis Market size is a direct consequence of an increase in R&D activity, increasing prevalent population, expected commercial success of upcoming therapies in the 7MM"

The potential drugs recently launched in Alpha Mannosidosis Market or expected to get launched in the market during the study period 2019-2032.

The Alpha Mannosidosis market report provides current treatment practices, emerging drugs, Alpha Mannosidosis market share of the individual therapies, current and forecasted Alpha Mannosidosis market Size from 2019 to 2032 segmented by seven major markets. The Report also covers current Alpha Mannosidosis treatment practice/algorithm, market drivers, market barriers and unmet medical needs to curate best of the opportunities and assesses the underlying potential of the market.

Key highlights of the Alpha Mannosidosis Market Research Report
• According to DelveInsight, the Alpha Mannosidosis Market in 7MM is expected to witness a major change in the study period 2019-2032
• Alpha-mannosidosis is inherited in an autosomal recessive manner and reported to affect 1 in 1,000,000 people worldwide. At conception, each sibling of an affected individual has a 25% chance of being affected, 50% chance of being an asymptomatic carrier.
• According to the Systematic Review of the Epidemiology of α-mannosidosis in 2017, the overall incidence of the disease globally ranges from 07 to 1.51 per 100,000 births. (Finocchiaro et al.)
• Alpha-mannosidosis affects men and women in equal numbers.

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Alpha Mannosidosis Overview
Alpha-mannosidosis (α-mannosidosis) is a rare lysosomal storage disorder with an autosomal recessive inheritance caused by mutations in the gene encoding for the lysosomal α-D-mannosidas. It is caused by the lack of the lysosomal enzyme-alpha-mannosidase due to a mutation in MAN2B1, located on chromosome 19 that causes disturbed glycoprotein catabolism leading to excessively high level of mannose-rich oligosaccharides in many tissues. This accumulation in various cells leads to the various complications in patients. It is a progressive disease with mental retardation, skeletal and muscle abnormalities, central nervous system involvement, recurrent infections, psychiatric symptoms, and compromised pulmonary function.

Alpha-Mannosidosis Epidemiology Insights
As per National Organization for Rare Disorder, Alpha-Mannosidosis is an ultra-rare progressive disorder that occurs in approximately 1 of 500,000 live births. Children are often born apparently normal, and their condition worsens progressively. Some children are born with ankle equinus or develop hydrocephalus in the first year of life (Malm et al.).

Alpha-Mannosidosis Epidemiology Segmentation in the 7MM
• Alpha Mannosidosis Prevalent Cases
• Alpha Mannosidosis Diagnosed and Treatable Cases
• Alpha Mannosidosis Severity-Specific Cases

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Alpha-Mannosidosis Treatment Market
Alpha-mannosidosis treatment is symptomatic and supportive. Therapy is directed at preventing and treating the complications of the disorder. Thus, it is important to be pro-active. Treatments to address individual symptoms are recommended as needed, such as vaccinations, antibiotics, hearing aids, glasses, orthopedic and other assistive devices, educational interventions, and speech therapy. Regular follow-up to monitor health and treatment response is advised. Current treatment options for alpha mannosidosis include bone marrow transplant or peripheral blood stem cell transplantation. Along with this, Enzyme replacement therapy may be an additional treatment option for the Alpha-mannosidosis

Alpha-Mannosidosis Market Insight
Given the broad range of symptoms experienced by patients, the large number of different healthcare professionals are likely to interact with the degenerative nature of the disease as alpha- mannosidosis places a large burden on patients and their families. With the recent approval of the in Lamzede in Europe, more number of patients may get benefited from this and its further expansion to other countries may boost the overall market, along with the R&D activities in this space.

Major Alpha-Mannosidosis Treatment Options
• Stem cell transplantation
• Enzyme Replacement therapy (Lamzede)
• Orthopedic interventions
• Antibiotics

Alpha-Mannosidosis Market Size
The increase in Alpha-Mannosidosis Market Size is a direct consequence of expected increasing awareness and increasing eligible population of Alpha-Mannosidosis patients in the 7MM.

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Scope of the Alpha-Mannosidosis Market Research Report
• Coverage- 7MM
• Study Period-2019-2032
• Forecast Period-2022-2032
• Alpha-Mannosidosis Market Companies- Chiesi, SmartPharma, and Many Others
• Alpha-Mannosidosis Market Drivers and Barriers
• Alpha-Mannosidosis Market Access and Reimbursement
• KOL Views

Table of Content
1. Key Insights
2. Executive Summary
3. Competitive Intelligence Analysis for Alpha-Mannosidosis
4. Alpha-Mannosidosis Market Overview at a Glance
5. Alpha-Mannosidosis Disease Background and Overview
6. Patient Journey
7. Alpha-Mannosidosis Epidemiology and Patient Population
8. Treatment Algorithm, Current Treatment, and Medical Practices
9. Alpha-Mannosidosis Unmet Needs
10. Key Endpoints of Alpha-Mannosidosis Treatment
11. Alpha-Mannosidosis Marketed Products
12. Alpha-Mannosidosis Emerging Therapies
13. Alpha-Mannosidosis Seven Major Market Analysis
14. Attribute analysis
15. 7MM: Alpha-Mannosidosis Market Outlook
16. Access and Reimbursement Overview of Alpha-Mannosidosis
17. KOL Views
18. Alpha-Mannosidosis Market Drivers
19. Alpha-Mannosidosis Market Barriers
20. Appendix
21. DelveInsight Capabilities
22. Disclaimer
23. About DelveInsight

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