Ion-Exchange Chromatography Market is projected to be worth USD 4,994.96 million by 2032 -Agilent Technologies, Bio-Rad, GE Healthcare, Merck, Thermo Fisher Scientific, Becton, Dickinson and Company, Helena Laboratories, Pall, Phenomenex, Regis Technologi

A market study Global examines the performance of the Ion-Exchange Chromatography 2022. Ion Chromatography Market Overview
The global ion chromatography market is projected to be worth USD 4,994.96 million by 2032, registering a CAGR of ~9.51% during the forecast period (2021-2032). The market was valued at USD 2,425 million in 201.

The ion chromatography market is driven by the increasing use of ion chromatography techniques for the process of protein purification, growing demand for monoclonal antibodies, and rising adoption of ion chromatography techniques in various applications such as food & beverage and pharmaceuticals. This is one of the major factors boosting the market growth. However, there are pitfalls in the market, such as risks of bacterial contamination and lack of skilled professionals to handle the equipment.

Pivotal players studied in the Ion-Exchange Chromatography report:

Agilent Technologies, Bio-Rad, GE Healthcare, Merck, Thermo Fisher Scientific, Becton, Dickinson and Company, Helena Laboratories, Pall, Phenomenex, Regis Technologies, Shimadzu, Tosoh, VWR, Waters Corporation, W.R Grace

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Market Drivers

Rising demand for ion chromatography in the pharmaceutical industry and drug analysis
Ion chromatography is a well-established and popular technique used to quantify and analyze charged species. Ion Chromatography (IC) has developed and matured into an important analytical methodology in various fields, including the pharmaceutical industry. However, reversed-phase chromatography is the most frequently used chromatographic method for analyzing drugs in the pharmaceutical sector. IC serves as an alternative method for ionic species that is often used to confirm the analysis of drugs, including sulfa drugs. The use of ion exchange and ion exclusion chromatography in the pharmaceutical industry is carried out to determine counterions and excipients in "off-the-shelf" drugs.
In addition, drugs such as gentamicin, neomycin, bethanechol chloride, and cefadroxil contain Active Pharmaceutical Ingredients (APIs) that can be determined by the IC method in compliance with regulatory standards such as the European Pharmacopoeia and US Pharmacopeia regulations. These regulatory standards and the rising adoption of IC techniques for drug determination are propelling market growth.
Growing food safety concerns
Increasing R&D funding for chromatographic techniques
Market Restraints

Risk of bacterial contamination during ion exchange
During ion chromatography, ion exchange resins do not remove microorganisms such as bacteria from the feed water, resulting in bacterial growth. The resin beds accumulate organic matter, which serves as a nutrient source for bacterial growth. This factor can result in limiting the market growth of ion chromatography.
The ion exchange resins beds can be treated with disinfectants such as formaldehyde but not with heat or chlorine, as they damage the resin. Furthermore, the lack of skilled personnel to handle the ion chromatography instruments is expected to restrain the market growth during the study period.
Market Opportunities

Increasing use of chromatography in the purification of monoclonal antibodies
According to the research articles published in Springerlink 2020, ion exchange chromatography is one of the most successful methods for preparing pure monoclonal antibodies (mAbs). An article published in Sciencedirect in 2020 states that the separation of charge variants is a challenge for monoclonal antibodies (mAbs) production. Cation exchange chromatography is being used to serve this purpose, further increasing the demand for procedures such as ion exchange chromatography.
In addition, ion exchange chromatography is also being used to monitor the heterogeneity in mAbs. It is useful because the protein remains in a native state, enabling collected fractions to be tested in a bioactivity assay to establish how a particular modification affects the functional activity of the mAbs.
Value Chain Analysis

The global ion chromatography market is growing steadily due to the emerging number of players in the market involved in new product launches, acquisitions, and strategic collaborations. The value chain analysis of the ion chromatography market comprises four major components starting with the R&D and designing, followed by manufacturing the products, distribution & sales, and ends with post-sales services.
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Product types uploaded in the Ion-Exchange Chromatography are:

Reagents, Instruments

Key applications of this report are:

Pharmaceutical industry, Healthcare sector, Industrial sector

Competitive Landscape

The ion chromatography market is profitable, both for existing players as well as new entrants. A substantial level of competitive rivalry is witnessed among the market players. Based on the analysis, market players have adopted different strategies and innovative R&D techniques to expand their business and secure their position in the global ion chromatography market. The prominent players are involved in new product launches & developments, strategic agreements, and joint ventures to mark their presence in the market. In addition, the presence of regulatory standards such as the United States Environmental Protection Agency (USEPA) and the American Society for Testing and Materials (ASTM) is also a stimulating factor for market growth.
The major market players are Thermo Fisher Scientific (US), Metrohm (Switzerland), Tosoh Bioscience (Japan), Shimadzu (Japan), Qingdao Shenghan Chromatograph Technology Co., Ltd (China), MembraPure GmbH (Germany), Nittoseiko Analytech Co., Ltd (Japan), Qingdao Puren Instrument (China), East & West Analytical Instruments (China), Qingdao Luhai (China), Sykam (Germany), and Cecil Instruments (UK).
Thermo Fisher Scientific (US) has a robust industry experience and is one of the leading companies in the ion chromatography market. Furthermore, a high customer satisfaction level, exceptional performance in new markets, and a strong product portfolio add to the company's competitive advantage.

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Segment Analysis

The global market for ion chromatography has been categorized into several segments based on application, technique, and region.

Based on technique, the global ion chromatography market is split into ion-pair chromatography, ion-exchange chromatography, and ion-exclusion chromatography. Among others, the ion-exchange chromatography segment accounted for the largest share across the market globally in 2020. The segment is likely to maintain its dominance over the assessment timeframe. The segment's growth is mainly attributed to the growing adoption of ion-exchange techniques across the globe.

Based on application, the global market for ion chromatography is split into the chemical industry, environmental testing, food industry, pharmaceutical industry, and others. The growing demand for the environmental testing segment is causing an upsurge in the global market's growth.

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