Press release
Digital Tornado to Drive the Unstable Angina Therapeutics Market
Anti-angina drugs are the therapeutics used in the treatment of angina pectoris. The condition is the result of myocardial ischemia which occurs due to an imbalance between myocardial blood supply and oxygen requirement. It is the symptom of coronary heart disease in which the arteries carrying blood to the heart become narrow or are blocked due to atherosclerosis.
Several diagnostic tests are performed in order to confirm the condition of angina such as ECG, stress test, echocardiogram, nuclear stress test, chest x-ray, blood tests, coronary angiography, CT scan, cardiac MRI, etc. Anti-angina treatment options include lifestyle changes, medications, angioplasty and stenting, or coronary bypass surgery.
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Segmentations-
By Disease Type
Stable Angina
Unstable Angina
Variant Angina
By Drug Type
Aspirin
Nitrates
Beta Blockers
Statins
Calcium Channel Blockers
Ranolazine
Angiotensin-converting enzyme (ACE) inhibitors
By Dosage Form Type
Oral Dosage Forms
Transdermal
Injectable
By Distribution Channel
Retail Pharmacies
Hospital Pharmacies
Drug Stores
Mail Order Pharmacies
By Region
North America
Latin America
Europe
Asia Pacific Excluding China
China
Middle East & Africa
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Nitrates are often used to treat angina as they relax and widen the blood vessels, which allow more blood to flow to the heart muscles. The U.S. FDA has recently approved nitroglycerin sublingual powder "Gonitro" of U.S.-based Espero Pharmaceuticals for acute relief of an angina pectoris attack in 2016.
Beta blockers works by blocking the effects of hormone epinephrine (adrenaline) which causes the heart to beat more slowly and with less force, thus reducing the blood pressure. Combining nitrates with β-blockers is most commonly used to block tachycardia and generating synergetic anti-ischaemic effect.
Oral dosage forms are the most commonly used for the management of angina. This includes normal and extended release tablets & capsules as well as sublingual dosage forms. These drug forms are available as labelled as well as off-labelled medications.
Cardiovascular diseases are the most common cause of deaths globally according to the WHO. Approx. 17.7 million people died from the heart diseases in 2015, representing 31% of all global deaths. High prevalence of ischemic heart disease has been a huge medical and social concern, thus representing a market opportunity for the market players in all the geographies.
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The trends in the development of anti-angina drugs include the use of synergistic combinations, ongoing clinical trials and other pharmacological developments including novel routes of administration, dosing regimen, etc. Further, clinical trials are being done to find out novel compounds for the treatment of angina capable of improving the quality of patients' life and minimizing the cost of healthcare.
The development of new drugs provides additional therapeutic options in the treatment of stable angina. Increasing competition in the generic version of the medicines is a threat for the market players.
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