Critical Limb Ischemia - Drug Pipeline Landscape, 2022

Critical limb ischemia is a serious form of peripheral arterial disease, or PAD where severe blockage in the arteries of the lower extremities (hands, feet and legs) occurs, which markedly reduces blood-flow. It results in severe pain and even skin ulcers or sores.
Peripheral artery disease causes chronic limb-threatening ischemia. Other causes of limb ischemia include embolisms, trauma and compartment syndrome.

The most common symptom of critical limb ischemia is ischemic rest pain. Other symptoms include pain or numbness in the feet, shiny, smooth, dry skin of the legs or feet and thickening of the toenails. Diagnosis methods of critical limb ischemia includes ankle brachial index test, duplex ultrasound scanning, magnetic resonance arteriography (mra), arteriogram, auscultation and CT angiography. Critical limb ischemia can be treated with medications, endovascular treatments and surgery.

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Report Highlights:

Global Insight Service's, Critical Limb Ischemia - Drug Pipeline Landscape, 2022 report provides an overview of the Critical Limb Ischemia pipeline drugs. This report covers detailed insights on Critical Limb Ischemia drugs under development, assessment by target, mechanism of action, route of administration and molecule type. Product pipeline by companies, stage of development and key regulatory designations, deals and milestones have been presented to provide insights and thus help industry participants in their decision making. Critical Limb Ischemia pipeline report helps gain insights on drugs which are under development stage of drug development process across globally.

Methodology:

The research process includes extensive secondary research on public domain and other authentic sources to add or update the pipeline products information. The secondary research sources include, but are not limited to company websites, annual reports, financial reports, company pipeline chart, investor presentations and SEC filings, journals and conferences, and clinical trials registries.

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Scope:

The pipeline landscape report provides analysis of pipeline products based on several stages of development ranging from Discovery to Pre-Registration. The report provides a review of pipeline therapeutics by companies based on information derived from company and industry-specific sources. The pipeline report covers assessment of therapeutics by mechanism of action (MoA), drug target, route of administration (RoA) and molecule type. Comprehensive profiles of the pipeline products with details such as company overview, development stage; molecule type, target, mechanism of action, route of administration, dosage form, regulatory designations, key deals, clinical trials, and key upcoming milestones are included.

Key Players:

- Ambulero, Inc.
- AnGes USA, Inc.
- Antidote Therapeutics
- Beijing Northland Biotech. Co., Ltd.
- BioGenCell Ltd
- Caladrius Biosciences, Inc.
- Cynata Therapeutics Limited
- Gurus BioPharm LLC

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