Gastroesophageal Junction Adenocarcinoma Market is expected to grow during the forecast period (2019-2032), Delveinsight | Key Companies- Sanofi, Shanghai Junshi, and Several Others

DelveInsight's Gastroesophageal Junction Adenocarcinoma Market Insights, Epidemiology, and Market Forecast 2032" report delivers an in-depth understanding of the disease, historical and forecasted epidemiology as well as the Gastroesophageal Junction Adenocarcinoma Market Size and Share in the 7MM (i.e. the United States, EU5 (Germany, Spain, Italy, France, and United Kingdom) and Japan).

The Gastroesophageal Junction Adenocarcinoma Market report covers emerging drugs, current treatment practices, market share of individual therapies, and the current forecasted market size from 2019 to 2032. It also evaluates the current treatment practice/algorithm, market drivers & barriers, and unmet medical needs to curate the best opportunities and assess the underlying potential of the market.

Gastroesophageal Junction Adenocarcinoma: An Overview
Gastroesophageal Junction Adenocarcinoma is a male-dominant aggressive malignancy and a leading cause of cancer-related mortality worldwide. Squamous cell carcinoma and adenocarcinoma are the two predominant histological subtypes with varying geographical and racial distribution. The risk of esophageal adenocarcinoma conferred by Barrett's esophagus depends on factors such as genomic instability, race and gender of the patient. Gastroesophageal Junction Adenocarcinoma is the eighth most common cancer worldwide, and the sixth most common cause of cancer-related deaths.

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Some of the key highlights of the Gastroesophageal Junction Adenocarcinoma Market Report
According to the National Organization for Rare Disorders: Approximately 17,000 people are diagnosed with Gastroesophageal Junction Adenocarcinoma in the United States each year. Squamous cell carcinoma and adenocarcinoma account for about 95% of people with Gastroesophageal Junction Adenocarcinoma. The number of people with squamous cell carcinoma is decreasing in the U.S., but the number of people with adenocarcinoma is increasing. The number of people with Gastroesophageal Junction Adenocarcinoma varies greatly throughout the world. It is the seventh most common cancer worldwide.
According to Mark Krasana et.al., Gastroesophageal Junction Adenocarcinoma continues to be a largely fatal malignancy, with overall five-year survival ranging from 15% to 20%. In USA, the incidence of EAC among white men was 0.4 per 100,000 in 1973 to 2.8 per 100,000 in 2012. A similar increase has been noticed in the United Kingdom, Australia, and Northern Europe. In these countries, the ratio of ESCC to EAC amongst white men was 4.7:1 in 1975, reduced to 0.43:1 in 1996-1998 (7,8). During this period, there was an 8-10% annual increase in incidence of EAC, though it has recently declined.
According to the Globocan, Gastroesophageal Junction Adenocarcinoma is the tenth most common malignancy and the seventh most common cause of cancer death in Japan, with an estimated 17 497 new cases and 11 746 deaths in 2008. The estimated overall age-adjusted incidence rate (standardized for world population) in 2008 was 5.7 per 100 000 population.

Gastroesophageal Junction Adenocarcinoma Market
The Gastroesophageal Junction Adenocarcinoma market size is anticipated to increase during the study period owing to the increasing incident population and rising awareness of the Gastroesophageal Junction Adenocarcinoma Market in the 7MM. The expected launch of emerging therapies and the research and development activities of pharmaceutical companies will also fuel the market growth during the forecast period.
The market outlook section of the report helps to build a detailed comprehension of the historic, current, and forecasted Gastroesophageal Junction Adenocarcinoma Market size by analyzing the impact of current and emerging therapies in the market. It also provides a detailed assessment of the market drivers & barriers, unmet needs, and emerging technologies.
The report gives a thorough detail of the Gastroesophageal Junction Adenocarcinoma Market trend for each marketed drug and late-stage pipeline therapies by evaluating their impact based on the annual cost of therapy, inclusion and exclusion criteria, mechanism of action (MoA), competition with other therapies, brand value, their impact on the market and view of the key opinion leaders.

Gastroesophageal Junction Adenocarcinoma Treatment Market
The therapeutic management of individuals with Gastroesophageal Junction Adenocarcinoma will require the coordinated efforts of a team of medical professionals such as physicians who specialize in the diagnosis and treatment of diseases of the digestive system (gastroenterologists), physicians who specialize in the diagnosis and treatment of cancer (medical oncologists), physicians who specialize in the diagnosis and treatment of cancer with surgery (surgical oncologists or thoracic surgeons), physicians who specialize in the use of radiation therapy for the treatment of cancer (radiation oncologists), oncology nurses, psychiatrists, nutritionists, and other healthcare specialists.

Gastroesophageal Junction Adenocarcinoma Market Insights
Targeted therapies are being explored as potential treatments for individuals with Gastroesophageal Junction Adenocarcinoma. Targeted therapies are drugs and other substances that prevent the growth and spread of cancer by blocking or inhibiting certain specific molecules (often proteins) that are involved in the development of specific cancers. Generally, targeted therapies are less toxic than other treatments for cancer.

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Gastroesophageal Junction Adenocarcinoma Epidemiology
The epidemiology section covers insights into the historical and current Gastroesophageal Junction Adenocarcinoma Market patient pool and forecasted trends for every seven major countries (7MM) from 2019 to 2032. It helps to recognize the causes of current and forecasted trends by exploring numerous studies and views of key opinion leaders. The epidemiology section also provides the diagnosed patient pool and their trends along with assumptions undertaken.

Gastroesophageal Junction Adenocarcinoma Market Drugs & Pipeline Development Activities
The drugs uptake section focuses on the rate of uptake of the potential drugs recently launched in the Gastroesophageal Junction Adenocarcinoma Market or expected to get launched in the market during the study period. The analysis covers Gastroesophageal Junction Adenocarcinoma market uptake by drugs; patient uptake by therapies; and sales of each drug.
Report's Drugs Uptake section helps in understanding the drugs with the most rapid uptake, reasons behind the maximal use of new drugs and allow the comparison of the drugs on the basis of market share and size which again will be useful in investigating factors important in market uptake and in making financial and regulatory decisions.
The report also covers the Gastroesophageal Junction Adenocarcinoma Market Pipeline Development Activities and provides valuable insights about different therapeutic candidates in Phase II, and Phase III stages and the key companies in the market involved in developing targeted therapeutics. It also analyses the recent Development such as collaborations, acquisitions, and mergers, licensing patent details, and other information for emerging therapies. Unmet needs in the Gastroesophageal Junction Adenocarcinoma include therapies that are oral, anthracycline sparing and deliverable in resource-limited settings. Another major unmet need is the relapse and refractory cases in the patients given treatment with Doxil.

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Gastroesophageal Junction Adenocarcinoma Market Dynamics
The dynamics of the Gastroesophageal Junction Adenocarcinoma market is anticipated to change in the coming years owing to the improvement in the diagnosis methodologies, and incremental healthcare spending across the world. The launch of several emerging therapies is expected during the forecast period of 2020-2030.

Gastroesophageal Junction Adenocarcinoma Emerging Therapies
The pipeline of Gastroesophageal Junction Adenocarcinoma is quite robust with several products available in the developmental stage. As per clinical trials.gov, there are several key players involved in the development of promising products such as Shanghai Junshi (Toripalimab), Jiangsu Hengrui Medicine (SHR-1210), Sunshine Lake Pharma (Larotinib), Innovent Biosciences (IBI308), Lee Pharmaceutical (ZKAB 001) Apexigen (APX005M), Takeda (Simurosertib) and others.

Gastroesophageal Junction Adenocarcinoma Companies
Sanofi
Shanghai Junshi, and several others
Gastroesophageal Junction Adenocarcinoma Drugs
Docetaxel
Toripalimab, and several others

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Table of content
1. Key Insights
2. Executive Summary
3. Competitive Intelligence Analysis
4. Market Overview at a Glance
5. Disease Background and Overview
6. Patient Journey
7. Epidemiology and Patient Population
8. Treatment Algorithm, Current Treatment, and Medical Practices
9. Unmet Needs
10. Key Endpoints of Gastroesophageal Junction Adenocarcinoma Market Treatment
11. Marketed Products
12. Emerging Therapies
13. Seven Major Market Analysis
14. Attribute analysis
15. 7MM: Market Outlook
16. Access and Reimbursement Overview
17. KOL Views
18. Market Drivers
19. Market Barriers
20. Appendix
21. DelveInsight Capabilities
22. Disclaimer
23. About DelveInsight

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