Global Nucleic Acid Isolation and Purification Market Top Companies, Business Growth & Investment Opportunities, Forecast by 2027

The global nucleic acid isolation and purification market size are expected to grow from USD 3.25 billion in 2021 to USD 5.9 billion in 2027. It will witness a CAGR of 9.1% during the forecast period.

Factors attributing to the growth of the nucleic acid isolation and purification market include technological development like robotic liquid handling in automated DNA extraction systems, reduction in cost related to genetic sequencing, and intake of personalized medicine and diagnostics will propel the market growth.

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Furthermore, the rising safety of workers, ability to produce timeless and accurate results are important prospects to achieve laboratory efficiency, thereby bolstering market development.

Moreover, the increasing research on genomics, molecular biology, precision medicine and enzymology along with substantial investment will further accelerate the industry growth of nucleic acid isolation and purification solutions. Nevertheless, the increased collaborations between industry payers in the biotech industry will drive the market growth.

The SARS-CoV-2 epidemic in China in late 2019 swiftly turned into a global pandemic, resulting in a significant need for efficient and economical diagnostic tests that could be used in both non-clinical and clinical settings. As a result of the growing demand for nucleic acid extraction kits, the major players have increased their manufacturing capacity.

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Market Segmentation

By Product
• Kits
• Instruments
• Reagents

Among the product, kits and reagents segment contributes the largest share in the nucleic acid isolation and purification market outlook due to the increased umber of research studies that emphasize the need to understand rare and common genome-based diseases.

By Method
• Column-Based
• Magnetic Bead-Based
• Reagent-Based
• Others

Based on method, the magnetic bead-based segment holds a significant share during the forecast period as it offers benefit to obtain the purest possible form of DNA/RNA and excludes other unwanted materials from the sample mixture.

For quick and efficient extraction, functionalized magnetic beads have been utilised in conjunction with appropriate buffer solutions in recent years.

This approach eliminates the need for centrifugation, which generally breaks down nucleic acids. As a result, an advantageous feature of this technique is that it allows for automated extraction with minimal centrifugation for nucleic acid isolation steps.

By Type
• Messenger RNA
• Plasmid DNA
• Circulating Nucleic Acid
• Total RNA
• Microrna
• PCR Cleanup
• Genomic DNA
• Others

Among the type, the total RNA isolation and purification segment dominate the market owing to the rising adoption to analyze COVID-19 samples and increased use of purified mRNA for the construction of the cDNA library that are adopted in several applications like clinical diagnostics, gene expression profiling, and sequencing.

By Application
• Precision Medicine
• Diagnostics
• Agriculture and Animal Research
• Drug Discovery & Development
• Others

Based on application, the diagnostics segment dominates the global nucleic acid isolation and purification industry due to the increased use of DNA and RNA isolation products in detecting and characterizing pathogens.

By End User
• Contract Research Organizations
• Academic and Government Research Institutes
• Hospitals and Diagnostic Centers
• Pharmaceutical and Biotechnology Companies
• Others

Based on end user, pharmaceutical and biotechnology companies will witness faster growth due to the surge in R&D activities for developing drugs. Moreover, hospitals and diagnostic centers will hold a significant share owing to the increased number of prenatal testings, liquid biopsies, and genetic fingerprinting will accelerate the growth of the segment.

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Geographical Analysis

North America contributes the largest share in the nucleic acid isolation and purification industry owing to intensive research projects to detect cancer ad other chronic diseases in the region, the presence of well-established players, and support from the government for biotechnology research in the region.

Recent Developments

In January 2022, QIAGEN N.V. launched three nucleic acid extraction kits that use fewer components and produce less waste than existing kits. They are the first of their kind to use both recycled plastics and space-saving chemical concentrates. The QIAwave RNA Mini Kit, QIAwave DNA Blood & Tissue Kit and QIAwave Plasmid Miniprep Kit use up to 63% less plastic and up to 42% less cardboard than QIAGEN's most popular kits for extracting DNA, RNA and plasmid DNA from samples. As a result, they are more environmentally friendly alternatives to existing products, a significant step in reducing QIAGEN's overall environmental impact.

In September 2021, Thermo Fisher Scientific, a global leader in science services, announced that it will manufacture its Applied Biosystems MagMAX Dx Prefilled Viral/Pathogen Nucleic Acid Isolation Kits in India for the Indian market. The kit isolates and purifies viral RNA and DNA from human saliva, nasopharyngeal, and oropharyngeal swabs, giving consumers a faster, more precise, and simpler solution.

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