Plant-Based Vaccines Market to Garner USD 2672.05 Million Globally by 2028 at 12.9% CAGR The Insight Partners

The plant-based vaccines market is expected to reach US$ 2,672.05 million by 2028 from US$ 1,143.72 million in 2021. The market is estimated to grow at a CAGR of 12.9 % from 2021 to 2028.

The report highlights trends prevailing in the market and factors driving its growth. The market growth is mainly attributed to increasing research & development (R&D) activities and the growing prevalence of infectious diseases. However, the potential risk of contamination and environmental risks of manufacturing the vaccines are likely to hamper the market's growth in the coming years.

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The scope of the plant-based vaccines market includes vaccine type, source, application, and geography. Based on region, the plant-based vaccines market is segmented into North America, Europe, Asia Pacific, Middle East & Africa, and South and Central America. The report offers insights and in-depth analysis of the plant-based vaccines market, emphasizing various parameters such as market trends and opportunities, market dynamics, and competitive landscape analysis of leading market players across North America, Europe, Asia Pacific, Middle East & Africa, and South and Central America. It also includes COVID-19 impact analysis across the regions.

Market Insights
Increasing Number of Research & Development (R&D) Activities in Plant-Based Vaccines
The lack of vaccines to prevent fatal diseases has created issues and prompted a worldwide focus on the development of safer, easier, and more effective vaccines. Plants are among the world's most prolific protein creators. Plants efficiently express proteins of various complexity and glycosylation patterns. Recombinant technology is used to create plant-derived vaccines, in which the gene encoding the required antigen protein is incorporated into the plant genome. Furthermore, experts estimate that the production of a plant-based vaccine takes five to six weeks instead of the five to six months required by vaccine makers to prepare the vaccine in chicken eggs. Many countries worldwide are developing an effective vaccine to combat the spread of COVID-19, and plant-based vaccines are one of the options for vaccine development. Plant-based vaccines have a good reputation among researchers because of their well-known successful manufacturing procedure and low cost. Various research and clinical trials are carried out for the development of plant-based vaccines. For instance, Medicago Inc. a clinical-stage biotechnology company that uses plant-based technologies to develop and produce novel vaccines and antibodies had successfully produced virus-like particles (VLPs) of the novel coronavirus just 20 days after obtaining the SARS-CoV-2 gene (the virus causing the COVID-19 disease). Existing prominent players and new entrants in the plant-based vaccines market are concentrating their efforts on conducting comprehensive clinical trials to produce plant-based vaccines for a variety of therapeutic applications. Hence, the increasing number of Research & Development (R&D) activities in plant-based vaccines will surge the demand for plant-based vaccines substantially across the world, leading to an upward thrust in the market's growth.

Impact of COVID-19 Pandemic on plant-based vaccines market:
The COVID-19 pandemic is adversely affecting industries worldwide. The outbreak led to significant disruptions in primary industries, such as manufacturing, healthcare, energy & power, electronics & semiconductor, aerospace & defense, and construction in 2020. In response to the need to control the spread of the COVID-19 infection among people, hospitals discontinued several services and redirected their operations toward the management of the disease. Moreover, hospitals and healthcare providers has to reassign their specialist doctors to various tasks in ICUs and other COVID-19-related wards. Care receivers also avoided visits to clinics for non-lethal conditions in the first and second quarters of 2020. However, due to increasing number of Covid-19 cases, the demand for the development of plant-based vaccines surged and resulted in the growth of the plant-based vaccines market.

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Based on vaccine type, the plant-based vaccines market is segmented into bacterial vaccines, viral vaccines, parasite vaccines, plant-derived virus-like particles (VLPS), and others. The bacterial vaccines segment held the largest share of the market in 2021. However, the plant-derived virus-like particles (VLPs) segment is anticipated to register the highest CAGR in the market during the forecast period. Bacterial vaccines may contain live bacteria that are attenuated, inactivated, or killed. Bacterial vaccines are categorized into toxoids, subunit vaccines, killed whole-cell vaccines, and live attenuated vaccines. Toxoids are chemically inactivated toxins from bacteria such as Corynebacterium diphtheria. The subunit vaccines consist only of a single antigen of the pathogen. For a subunit, the immune response is lower than a whole cell. The inactivated vaccines contain killed bacterial cells that are inactivated through chemical, heat, or radiation treatment of the disease-causing bacteria. Live vaccines are attenuated living bacteria. Attenuation can be achieved through spontaneous or targeted mutation of various genes essential for virulence; an example is the Ty21a typhoid vaccine. The major pathogens of plants are parasitic plants, and bacteria including bacterial Pseudomonas syringea pv. that causes necrotic lesions surrounded by yellow chlorotic halos on tomatoes. It reduces yields, and affects fruit quality.

Veterinary Vaccines Market: Competitive Landscape and Key Developments
MEDICAGO, INC.; British American Tobacco p.l.c.; ICON GENETICS GMBH; CREATIVE BIOLABS, INC.; iBio, Inc.; LENIOBIO; Lumen Bioscience, Inc.; LEAF EXPRESSION SYSTEMS LTD.; ZYUS LIFE SCIENCES INC.; and FRAUNHOFER CMB are among the leading companies in the plant-based vaccines market.

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