Narcolepsy Drug Market Global Demand, Competitive Landscape and Business Outlook 2021 - Teva Pharmaceutical Industries Ltd., Arena Pharmaceuticals, Shire Plc

The Global Narcolepsy Drug Market size was valued at USD 2.65 billion in 2019, and is predicted to reach USD 6.48 billion by 2030 with a CAGR of 8.4% from 2020-2030.

Narcolepsy is an orphan disease causing a long-term neurological disorder resulting into decreased ability in regulating sleep-wake cycles. The loss of brain-chemical called hypocretins (orexins) causes narcolepsy. Its symptoms are excessive daytime sleepiness, sleep attacks, disrupted night-time sleep, and in some cases, cataplexy, hallucinations, and/or sleep paralysis are observed.

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Competitive Landscape

The narcolepsy drug market, is consolidated as it has few major players such as Teva Pharmaceutical Industries Ltd., Arena Pharmaceuticals, Shire Plc, Addrenex Pharmaceuticals, Jazz Pharmaceuticals Plc., Bioprojet, Ligand Pharmaceuticals, and Graymark Healthcare, Inc. among others.

The global narcolepsy drug market is gaining momentum due to an upsurge in R&D activities and proliferating number of drugs manufactured by key players, which are achieving FDA approval.

For instance, In February 2019, Harmony Biosciences LLC., a leading company in narcolepsy drug market, announced that the FDA has accepted for filing the NDA for its investigational product, ‘PITOLISANT’, a highly selective histamine-3 (antagonist/inverse agonist receptor); and has granted Priority Review for this NDA. In patients suffering from narcolepsy, PITOLISANT offers treatment options for both excessive daytime sleepiness and cataplexy.

In September 2019, at the World Sleep Congress, research data presented by Takeda Pharmaceutical Company Limited, a leading manufacturer in narcolepsy drug market demonstrated that ‘TAK-925’, a selective Orexin Type-2 Receptor (OX2R) Agonist, showed early signs of effectiveness in the patients suffering from narcolepsy type-1. The studies also evaluated tolerability, safety, pharmacodynamic and pharmacokinetic effects of TAK-925.

Furthermore, in March 2020, Jazz Pharmaceuticals, one of the major players in narcolepsy drug market, announced that the FDA has accepted for filing the NDA with priority review for its ‘JZP-258,’ a novel oxybate-product candidate with unique cation composition, used for the treatment of both excessive daytime sleepiness and cataplexy in patients ageing 7 years and above.

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Market Segmentations and Scope of the Study:

The global narcolepsy drug market share has been analyzed based on disease type, diagnosis, drug type, and geography.

Based on disease type, the market is segmented into narcolepsy type I and narcolepsy type II. Based on diagnosis, the market is divided into Polysomnogram, and Multiple Sleep Latency Test. Based on the type of drug, the market is fragmented into Tricyclic Antidepressants, Central Nervous System Stimulants, Selective Serotonin Reuptake Inhibitor, Sodium Oxybate, and others. Geographic breakdown and analysis of each of the previously mentioned segments include regions comprising North America, Europe, Asia-Pacific, and RoW.

Geographical Analysis

North America represents high prevalence rate of sleep disorders due to unhealthy lifestyles as well as increased consumption of alcohol and tobacco. Furthermore, the increase in research and development activities, constant increase in FDA approval of drugs, and developed healthcare infrastructure are supplementing the growth of the narcolepsy drug market.

It is expected that the emerging economies, specifically in the Asia-Pacific region would witness increasing market size owing to fast developing healthcare facilities in this region. Additionally, increasing awareness about sleep disorders, and growing adoption of narcolepsy drugs, are further expected to augment the growth of narcolepsy drug market over the forecast period.

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