Global Exosome Technologies Market potential Segments Their Contribution To Market Size - Aegle Therapeutics, Anjarium Biosciences, Aruna Biomedical, Carmine Therapeutics

Exosome Technologies Market: Introduction
According to the report, the global exosome technologies market was valued over US$ 31 Mn in 2020 and is projected to expand at a CAGR of ~24% from 2021 to 2031. Exosomes are extracellular vehicles secreted from human body cells. Exosomes play a crucial role in the intercellular transportation of protein and RNA. Recently, exosomes have been tested for numerous therapeutic applications, including biomarkers, drug delivery systems, and therapies for diseases such as cancer, renal neurological, and cardiovascular diseases. Increase in awareness about exosome technologies & government initiatives are the key factors projected to drive the global exosome technologies market during the forecast period. North America held major share of the global exosome technologies market in 2020, owing to high incidence rate of chronic diseases such as cancer and cardiovascular diseases, technological advancements, and rise in acceptance of these technologies in the region. Moreover, strategies adopted by key players are anticipated to augment the market in the U.S. The exosome technologies market in the Asia Pacific is expected to expand at a CAGR of 8.5% from 2021 to 2031 due to government initiatives to improve healthcare infrastructure.

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Rise in Prevalence of Chronic Diseases to Drive Global Market
The prevalence of cardiovascular diseases has increased across the globe due to change in dietary habits. According to Centers for Disease Control and Prevention statistics, heart diseases account for nearly 655,000 deaths in the U.S. each year. Cancer is also a leading cause of death globally, caused due to lifestyle-related factors such as alcohol consumption, tobacco consumption, and some food-related factors. According to the World Health Organization statistics, in 2018, an estimated 18.1 million new cases of cancer and 9.6 million deaths were reported across the globe. Aging is considered a major risk factor for neurodegenerative diseases. Therefore, a surge in the geriatric population contributes to the increase in the number of patients with various brain diseases. Moreover, changing environmental conditions and human behavior affect the spread and impact of infectious diseases. Therefore, rise in prevalence of various chronic diseases is likely to boost the global exosomes technologies market during the forecast period.

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Loaded Cargo Held Major Share of Exosome Technologies Market
In terms of exosome type, the global exosome technologies market has been bifurcated into loaded cargo and non-cargo. The loaded cargo segment dominated the market in 2020. Exosomes carry various types of proteins, lipids, and nucleic acids (mRNA and non-coding RNA). Exosomes with therapeutic cargo help to cross the natural membranous barriers, such as the blood-brain barrier (BBB), to achieve better therapeutic efficiency of brain diseases. This, in turn, is projected to drive the segment.
MSCs Dominated Exosome Technologies Market
Based on cell source, the global exosome technologies market has been classified into HEK293, MSCs, platelets, erythrocytes, natural killer cells (NKs), and others. The MSCs segment dominated the global exosome technologies market in 2020, and the trend is anticipated to continue during the forecast period. MSCs have immunomodulatory properties to regulate various cells involved in immune responses and exhibit potent cell therapeutics for various diseases for the last few decades. This factor is expected to propel the segment.

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Diagnostics to Lead Global Market
In terms of indication, the global exosome technologies market has been categorized into therapeutics and diagnostics. The diagnostics segment held major share of the global exosome technologies market in 2020. The segment’s dominance can be attributed to reimbursement, availability, and approval of new exosome diagnostics products.
Healthcare Providers to be Key End Users
Based on end user, the global exosome technologies market has been divided into healthcare providers, pharmaceutical & biotechnology companies, and others. The healthcare providers segment held a major share of the global exosome technologies market in 2020. The segment’s dominance can be attributed to the increase in the geriatric population suffering from various diseases.
North America to Dominate Global Market
In terms of region, the global exosome technologies market has been divided into North America, Europe, Latin America, Asia Pacific, and Middle East & Africa. North America is projected to account for prominent share of the global exosome technologies market during the forecast period. Extensive in-house manufacturing & research capacity, large customer base, and a well-established healthcare infrastructure are the major factors driving the market in North America. The market in Europe is anticipated to expand at a high CAGR in the near future, owing to strategies adopted by key players and grants of patent for exosomes in the region. The exosome technologies market in Asia Pacific is projected to grow at a rapid pace in the near future. This can be attributed to government initiatives to improve healthcare infrastructure. For instance, the Government of Japan and a team of industry players announced a collaboration leveraging exosomes to improve cancer diagnosis and its treatment.

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Growth Strategies of Key Players
Key players operating in the global exosome technologies market are Aegle Therapeutics, Anjarium Biosciences, Aruna Biomedical, Carmine Therapeutics, Ciloa SAS, Codiak BioSciences, Creative Biolabs, Danaher Corporation (Beckman Coulter), Direct Biologics, ExoCan Healthcare Technologies Pvt. Ltd., ExoCoBio, ExonanoRNA LLC, Exopharm, Exosome Diagnostics, Inc. (BIO-TECHNE CORPORATION), Fujifilm, ILIAS Biologics, Inc., Illumina, Inc., Invitrix Therapeutics, XOStem, Inc., VivaZome Therapeutics Pty Ltd., Thermo Fisher Scientific, Inc., Organicell, OmniSpirant Ltd., and Novadip Biosciences. These companies engage in research & development to develop novel products in order to expand product offerings and customer base. For instance, in June 2020, Sarepta Therapeutics, Inc. entered into a collaboration with Codiak BioSciences to research and develop exosome-based therapeutics for rare diseases.

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