Targeted Therapeutics Market Segments, Leading Player, Application and Forecast Analysis

Targeted therapies are drugs or other substances that block the growth of unwanted cells and pathogens by interfering with specific molecules ("molecular targets") involved in the growth, progression, and spread of disease. Targeted therapies are sometimes called molecularly targeted drugs, molecularly targeted therapies, precision medicines, etc. The emerging field of target therapeutics offers varied potential treatments. Target therapies involves a wide range of therapies, such as, gene therapy, which uses genetic material to alter cells (either in vivo or in vitro) to help cure disease , and stem cell therapy, that can be obtained from a very initial stage in human development and has the prospect to develop all the cell types in the human body. Targeted therapies offer the possibility of finding a cure for diseases with significant unmet needs, including orphan diseases and diseases having a high burden globally.

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Rise in the number of newly diagnosed patients, rigorous research & development activities, adverse side effects of conventional therapies, and a rise in public awareness toward chronic illnesses across the world are the major factors driving the growth of the global targeted therapeutics market. Additionally, favorable reimbursement policies available in developed countries are projected to boost the growth of the targeted therapeutics market. However, high cost of the treatment, lack of favorable reimbursement schemes in developing economies, unavailability of the treatment in the Asian and African countries, such as, Thailand and the Philippines, and a shortage of skilled professionals are likely to restrain the growth of the targeted therapeutics market during the forecast period. Nevertheless, there are a number of late-stage pipeline candidates that are expected to generate strong annual revenue during the forecast period; for example, PD-1 inhibitor durvalumab for bladder cancer, head and neck cancer, liver cancer, renal cell carcinoma and the CDK-4 and -6 inhibitor abemaciclib for glioblastoma, liposarcoma, and mantle-cell lymphoma. Newer CAR-T cell therapies, Tisagenlecleucel-T and KTE-C19, are also expected to make an entry into the market and generate blockbuster revenues.

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The global targeted therapeutics market can be segmented based on drug type, application type, distribution channel, and region. In terms of drug type, the targeted therapeutics market can be divided into monoclonal antibody therapeutics, protein/peptide therapeutics, small molecule drugs, RNA interference, stem cell therapy, and gene therapy. The monoclonal antibodies segment is likely to hold the leading share of the market during the forecast period; there are currently 73 monoclonal antibodies (mAb) approved for various indications with the purpose of extending the patient’s lifespan. The current market leader is Humira, which generated revenue of US$ 18.4 Bn in 2017 across a number of indications. Based on application, the market can be classified into immunology, oncology, infectious diseases, and others. Oncology is projected to be the leading segment of the market, in terms of market share, during the forecast period due to the high prevalence of the disorder and high level of use of immunotherapies in treatment regimes. Pharmaceutical companies worldwide are focused on developing target therapies to combat cancer at all stages and also for the treatment of the disease. In terms of the distribution channel, the market can be categorized into drug stores, retail pharmacies, hospital pharmacies, and online sales.

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