Hexamethylphosphoramide Market Consumption and Revenue Analysis by Regions, Application to 2029

Hexamethylphosphoramide Market Snapshot:

Hexamethylphosphoramide (HMPA) refers to a colorless organic liquid medium ammonia flavor that is found to be soluble in both polar and non-polar solvents. It is a highly efficient organic catalyst that is responsible for the reversible-deactivation radical polymerization of methyl methacrylate. It is made from the reaction of dimethylamine and phosphorus oxychloride and is used as a polymer-solvent for various applications such as a laboratory solvent for organometallic and organic reactions, selective solvent for gases, and a stabilizer in polystyrene against thermal degradation. Hexamethylphosphoramide helps in improving the selectivity of certain organic reactions. It can be used as an anti-corrosion agent of PVC and other kinds of chlorine, which contains resin products and coatings. It is also used as an ultraviolet inhibitor, gas chromatographic fixative, and rocket fuel additives for lowering the freezing point.

They are used in the industrial application sector and are in high demand in several niche markets. In addition to this, it is used as a chemosterilant for a number of insect pests and chemical mutagen as it causes reproductive sterility in an organism. It is used to control the economically destructive or disease-causing pests, which are done by either causing temporary or permanent sterility of one or both of the sexes. Furthermore, it is also used as a weathering solvent of polyvinyl chloride and polar solvent, which significantly affects the aging and low-temperature resistance of the agricultural films.

Apart from this, it is used in a variety of processes and applications, such as a solvent, chemosterilant, gas chromatographic fixative, and thermal stabilizer. It is used as a solvent to convert carboxylate salt into esters by reacting with alkyl halides. Esters are a chemical amalgamation between alkyl and a substitute for hydrogen of an acid. Some of the naturally obtained esters include oils, fats, and triglycerides, which have the least impact on the health of humans and are continuously in demand due to their high-performance and custom design versatility.

Solar energy is the most convenient renewable solution and a highly efficient form of unconventional energy that reduces greenhouse emissions and global warming. The solar industry has been growing rapidly, owing to the increasing environmental pollution and initiatives and support from various governments across the globe to install solar panels. Apart from this, the demand for solar energy systems is witnessing a significant surge in the power generation sectors. As per Solar Power Europe, solar energy alone reached a total share of 12.1% in the global total power output in 2017.
As per the Journal of Materials Chemistry, a 17% efficient perovskite solar mini-module was created with hexamethylphosphoramide (HMPA) as the lewis base additive. Perovskite solar cells convert visible light and ultraviolet into electricity. They also have tunable bandgaps, which means they can be easily custom-designed and hexamethylphosphoramide has helped in forming a denser and uniform perovskite film with high optoelectronic quality.

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The Major Prominent Players Covered in this Report:
BASF SE
Masuda Chemical Industries Co Ltd
Alfa Chemistry
CarboMer
Apollo Scientific Ltd
AccuStandard
Dr Ehrenstorfer GmbH
Ningbo Huajia Chemical Co Ltd
Jiangxi JixiangPharmchemical Chemical Co Ltd.
Jinan FuFang Chemical Co Ltd

By Type, 0%–99.5%, >99.5%,
By Form, Specialty Solvent, Oxidant

Growing Domestic Demand and Expanding Pharmaceutical Sector to Drive the Demand for Hexamethylphosphoramide in the APAC Region
Asia-Pacific region is anticipated to hold the largest market share in the global Hexamethylphosphoramide market during the forecast period 2021-2029. The growth in this region can be attributed to the presence of emerging economies like India, China, Japan, Vietnam, and Indonesia, which account for the largest share in this region. India is one of the largest producers of Hexamethylphosphoramide and a major exporter of the product to various countries across the globe. India accounts for around 80% of the world’s exports of Hexamethylphosphoramide. The favorable climatic conditions and growth of agricultural inputs and allied services like cold storage and warehousing in India are prompting higher production.

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Use of Hexamethylphosphoramide in PVC -
The increased use of PVC in different industries is anticipated to surge the demand for hexamethylphosphoramide during the forecast period.

PVC refers to a very durable and long-lasting material, which falls into the category of thermoplastic resins that are hard plastics but can be softened through heating. It is made of 57% chlorine and 43% carbon and uses more renewable resources for its production. PVC is the world's third-most widely produced synthetic plastic polymer that is versatile, durable, affordable, and recyclable. It is used for a broad range of applications, such as window frames, cables, sports equipment, pipes, flooring, furniture, and a range of life-saving medical devices.

Hexamethylphosphoramide acts as the light stabilizer of PVC, which enables amazing anti-aging properties of outdoor products and excellent weather resistance. Thus, the use of hexamethylphosphoramide in PVC is increasing, further increasing the demand for PVC in various industries for its various advantages. As per the European Council of Vinyl Manufacturers, around 70% of the PVC is used for durable, affordable, and recyclable building and construction products. The council also stated that in the EU-28, about 6.5 million tons of PVC products are manufactured every year, further driving the demand for hexamethylphosphoramide.

Toxic Effects of Hexamethylphosphoramide -
The carcinogenic solvent of hexamethylphosphoramide hinders the market growth. The researchers are compelled to look for better options, such as DMI, due to safety reasons. As per the Journal of Chemical Ecology, 19 out of 21 carcinogens are active in HMPA, whereas 3 out of 6 non-carcinogens were active in the Drosophila system.

Hexamethylphosphoramide is known to have toxic effects on experimental animals. The repetitive application of hexamethylphosphoramide on the skin of rabbits leads to weight loss, neurological disorders, and changes in gastric functions. Additionally, it initiates acute poisoning in rats leads to severe bronchiectasis and bronchial pneumonia. The oral administration of this liquid can cause semen deficiencies and testicular atrophy.

According to various studies, it has also been seen that upon inhaling HMPA, the rats start showing nasal tumors after eight months after getting exposed to 400 to 4000 ppb HMPA. In some of the mice, cancer has also been shown to be initiated. Therefore, the use of hexamethylphosphoramide on animals may get restricted in the near future.

Key Hexamethylphosphoramide Market Trends:
- The report identifies, determines, and forecasts the Global Hexamethylphosphoramide Market segments based on their type, sub-type, technology used, applications, end-users, and regions.
- Industry to Industry Holds Largest Share in the Hexamethylphosphoramide Market
- It examines the micro-markets based on their growth trends, development patterns, future prospects, and contribution to the overall market.
- Demand from Regional / geographical is Expected to Drive the Growth
- Rising Adoption of Market Segments in this Growth
- North American, Europe is Expected to Witness Higher Growth Rate over the Forecast Period
- It studies the competitive developments such as partnerships and collaborations, mergers and acquisitions (M&A), research and development (R&D) activities, product developments, and expansions in the Global Hexamethylphosphoramide Market.

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