Crude Heparin Market Size to Surge Vigorously during the Forecast Period

Crude Heparin: One of the Most Widely Used Natural Products in Medicine

Heparin is a widely used, strongly charged polysaccharide anticoagulant agent. It is used as a drug and incorporated in devices.
Heparin is used to treat and prevent blood clots caused by certain medical conditions or medical procedures. It is also used before surgery to reduce the risk of blood clots.
Crude heparin is obtained primarily from bovine and porcine sources. Moreover, it has been obtained from other animal and human sources in the past few years. Crude heparin brings some natural impurities, which are purified and processed for pharmaceutical and commercial use purpose.
Crude heparin is the base material intended for processing for heparin sodium USP API (active pharmaceutical ingredient), not a finished drug product. This is approved for final formulation by US FDA & other regulatory bodies and it is an upstream raw material for heparin.
The three major steps in the heparin manufacturing process are: extraction from animal intestines, separation of polysaccharide material, and purification with different acid and base wash
Typical heparin supply chain includes slaughterhouses, crude manufacturers, and consolidators or API manufacturers to finished dosage form (FDF) manufacturer to final end users

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Key Drivers and Restraints of Global Crude Heparin Market

Rise in prevalence of various diseases, particularly cardiovascular diseases, has fuelled the demand for heparin finished dosage forms. This in turn has created significant opportunities in the global crude heparin market.
Changing lifestyle habits such as alcohol consumption, poor nutrition, obesity, and smoking have increased the prevalence of cardiovascular diseases such as pulmonary embolism, deep vein thrombosis, and venous thromboembolism
Heparin is the most common anticoagulant used for the prevention and treatment of diseases mentioned above. Hence, rise in prevalence of these diseases contribute to the growth of the global crude heparin market.
According to the Centers for Disease Control and Prevention (CDC), around 900,000 people could be affected (1 to 2 per 1,000) by venous thromboembolism in the U.S. each year
Moreover, growing regulatory compliance for manufacturing crude heparin to eliminate contaminants for pharmaceutical grade products and rise in awareness about heparin in developing regions fuel the growth of the global crude heparin market
Larger animal base used as a source for crude heparin and technological advancements for processing crude heparin are the other factors boosting the growth of the global crude heparin market

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Higher Contaminants in Raw Material to Hamper Global Crude Heparin Market

Higher impurities and contaminants in natural heparin, which can cause serious side effects in end-users, is likely to hamper the growth of the global crude heparin market
Several cultural, religious norms in certain regions and countries such as ban on porcine heparin in Gulf countries is projected to restrain the global crude heparin market

Porcine Segment to Dominant Global Market

In terms of source, the global crude heparin market can be divided into porcine, bovine, and others
The porcine segment accounted for major market share in 2019 due to clinically proven therapeutic efficacy, easy availability of animals, and recent regulatory norms for purification of final product

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Low Molecular Weight Heparin (LMWH) to be Highly Attractive Segment

Based on application, the global crude heparin market can be bifurcated into low molecular weight heparin (LMWH) and unfractionated heparin (UFH)
The low molecular weight heparin (LMWH) segment dominated the global crude heparin market in 2019 and the trend is expected to continue during the forecast period
LMWH is projected to be a highly lucrative segment from 2020 to 2030 owing to higher demand for LMWH in therapeutics, less risk of side effects, and advanced methods of production

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Key Players Operating in Global Crude Heparin Market

 Key players operating in the global crude heparin market are:

Shenzhen Hepalink Pharmaceutical Group
Fengrun Biological Technology
Hepac (Darling Ingredients)
Scientific Protein Laboratories
Pharma Action (Tönnies Group)
Nanjing King-friend Biochemical Pharmaceutical
Aspen Oss
Changzhou Qianhong Biopharma
Yantai Dongcheng Biochemicals
Huaian MDC Pharmaceutical

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