Alagille Syndrome Market 2020-2026 Moving Towards Brighter Future | Major Giants – Endo Pharmaceuticals Inc, ANI Pharmaceuticals, Inc, Mylan N.V., Glenmark Pharmaceuticals Ltd, Amneal Pharmaceuticals LLC

In Alagille Syndrome Market report, a systematic investment analysis has been performed which forecasts impending opportunities for the market players. The statistical and numerical data that has been included in this market report is represented with the tables, graphs and charts which eases the understanding of facts and figures. A proficient data and excellent forecasting techniques used in this report are synonymous with accurateness and correctness. Alagille Syndrome Market report is a painstaking analysis of existing scenario of the market which covers several market dynamics. The market study of this global Alagille Syndrome Market business report takes into consideration market attractiveness analysis where each segment is benchmarked based on its market size, growth rate & general attractiveness.

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Global Alagille syndrome market is expected to grow at a substantial CAGR in the forecast period of 2019-2026. Presence of refined healthcare infrastructure and increase in special designation from the regulatory authorities are the key factors that drive the market.

Few of the major competitors currently working in the global Alagille syndrome market are Albireo Pharma, Inc, Mirum Pharmaceuticals, Teva Pharmaceutical Industries Ltd, Zydus Cadila, ALLERGAN, Endo Pharmaceuticals Inc, ANI Pharmaceuticals, Inc, Mylan N.V., Glenmark Pharmaceuticals Ltd, Amneal Pharmaceuticals LLC, Epic Pharma, LLC, Lannett, Fresenius Kabi AG, Lannett, Novartis AG, Pfizer, Inc, Lupin, Hikma Pharmaceuticals PLC, Akorn, Incorporated and others.

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Market Definition: Global Alagille Syndrome Market

Alagille syndrome is a rare autosomal dominant genetic disorder that affects multiple organ system of the body most commonly in the liver, heart, skeleton, eyes and kidneys. It is associated with liver diseases, hepatomegaly, and biliary atresia and in severe cases liver transplantation may be necessary. Alagille syndrome is caused by either mutation in the JAG1 gene or deletion in genetic material on chromosome 20 that include the JAG1 gene. These proteins is necessary for Notch signaling between neighboring cells during embryonic development and error in genes results in abnormalities in the bile ducts, heart, spinal column, and certain facial features

According to the statistics published in the U.S. Department of Health & Human Services, an estimated annual prevalence of Alagille syndrome worldwide is 1 in 70,000 newborns. Introduction of the drugs used to treat complication associated with Alagille syndrome and presence of refined healthcare infrastructure is fueling the growth of this market

Key Developments in the Alagille Syndrome Market:

In April 2019, Mirum Pharmaceuticals presented a phase II ICONIC clinical trial study data at The International Liver Congress 2019 for maralixibat for the treatment of Alagille syndrome. The trial has demonstrated the well tolerated dose with no serious adverse events as well as durable improvements in itch severity and serum bile acids in children with Alagille syndrome. If trial successful, it could became first approved treatment for patients suffering from Alagille syndrome.
In October 2018, Albireo Pharma, Inc received an Orphan Drug designation from the FDA for A4250, an ileal bile acid transporter (IBAT) inhibitor for the treatment of Alagille syndrome. A4250 also hold the PRIority MEdicines (PRIME) designation and Orphan Drug designation from both the FDA and EMA for the treatment of progressive intrahepatic cholestasis (PFIC). With this designation, company can obtain regulatory and financial incentives for development along with 7 year market exclusivity.

Alagille Syndrome Market Drivers

Increase in special designation from the regulatory authorities is drive the market
Growing prevalence of cancer has boosted the development of the novel treatments can enhance the market growth
Rise in number of patients suffering from paragangliomas and continuous advances in the treatment is propelling the market growth
Huge financial support to the researchers for developing novel intervention is boosting the market growth

Alagille Syndrome Market Restraints

Rise in cases of product recalls are expect to cause a shortfall in the market
Limited operating revenue opportunities for research and development of targeted therapies by many pharmaceuticals is acting as a challenging factor for the growth of this market
Lack of healthcare budget in some middle-income countries is restraining the market growth

Opportunities in the Alagille Syndrome Market Report :-

Comprehensive quantitative analysis of the industry is provided for the period of 2020-2026 to assist stakeholders to capitalize on the prevailing market opportunities.
Comprehensive analysis of the factors that drive and restrict the market growth is provided in the Alagille Syndrome Market report.
Extensive analysis of the key segments of the industry helps in understanding the trends in types of point of care test across regional.
Extensive analysis of the key segments of the industry helps in understanding the trends in types of point of care test across Global.

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