Macular Edema Market is Striving in Worldwide with Top Key Players: Acucela Inc., BCN Peptides, Aerie Pharmaceuticals, Inc., Aerpio Therapeutics, Inc., Many Other

The exact disease etiology of diabetic macular edema is not known, but the research findings in the clinical trials states that it is a neurovascular disease of macula region present in retina. Altered glial cells, death of endothelial cells and loss of pericytes has increased the vasopermiability. The other factors studied that trigger the disease are upregulation of VEGF factors and activation of AGE receptors. The treatment regimen adopted for diabetic macular edema has undergone changes since 1985 as laser photocoagulation therapy to post 2005 as intravitreal injections and implants of Anti-VEGF drugs. As per the research citing of American Academy of Ophthalmology report 2015, approximately 21 million people globally are suffering with diabetic macular edema.

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Photocoagulation laser therapy is employed for the treatment of patients suffering with focal diabetic macular edema, with preference given to yellow pattern 577 nm micropulse lasers. Anti-VEGF drugs are formulated as intravitreal implants and intravitreal injections for the treatment of patients suffering with diffuse diabetic macular edema.

Increase in the prevalence and incidence of diabetes has increased the risk of diabetic macular edema, making it the major driver of the market. Furthermore, increased use of off-label drugs, such as Avastin (bevacizumab) by Roche, and the emergence of new drugs in the market further boost the market growth. Moreover, recently two drugs Ozurdex manufactured by Allergan and Lucentis developed by Roche and Novartis, which are used for the treatment of macular edema, received regulatory approvals, thus boosting the market growth. Furthermore, rise in funding for the R&D activities to tackle the burden of these chronic diseases by medical organizations and pharmaceuticals companies boosts the market.

As per the study conducted by International Diabetes Federation (IDF), approximately 284 million people, almost equivalent to half of the European population are suffering from visually impairments out of which 39 million of them are totally blind. These kinds of diseases in addition to the human aspects also carry significant social as well as economic impact. Medical organizations and pharmaceuticals companies are investing substantially into R&D, infrastructure and technology to tackle the burden of these chronic diseases. DME only affects a certain percentage of diabetic patients; its percentage is likely to grow in the coming years. The number of people suffering from diabetes in Europe is speculated to rise from 55.2 million in 2010 to 66.2 million by 2030, DME cases would increase proportionately. There are several anti VEGF compounds which are being manufactured and currently into research phase. Asia-Pacific region is expected to be one of the emerging markets for DME treatment, as the diabetic population in the developing nations such as India, China and Indonesia are pacing up exponentially.

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Comprehensive competitive analysis and profiles of major players, such as Acucela Inc., BCN Peptides, Aerie Pharmaceuticals, Inc., Aerpio Therapeutics, Inc., Amakem NV, Biomar Microbial Technologies, Antisense Therapeutics Limited, Charlesson LLC., Araim Pharmaceuticals, Inc., and Coherus BioSciences, are also provided in this report.

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