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Alpha-1 antitrypsin deficiency (AATD) Market 2020 Overview by Experts to 2026

09-29-2020 05:24 AM CET | Health & Medicine

Press release from: Market Insights Reports

Alpha-1 antitrypsin deficiency (AATD) Pipeline Insight, 2020

The report will make detailed analysis mainly on in-depth research on the development environment, Market size, development trend, operation situation and future development trend of Alpha-1 antitrypsin deficiency (AATD) Market on the basis of stating current situation of the industry in 2020.

This is a latest report, covering the current COVID-19 impact on the market. The pandemic of Coronavirus (COVID-19) has affected every aspect of life globally. This has brought along several changes in market conditions. The rapidly changing market scenario and initial and future assessment of the impact is covered in the report. It offers critical information pertaining to the current and future growth of the market.

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Alpha-1 antitrypsin deficiency (AATD) Pipeline Insight, 2020, report provides comprehensive insights about 25+ companies and 25+ pipeline drugs in Alpha-1 antitrypsin deficiency pipeline landscape. It covers the pipeline drug profiles, including clinical and nonclinical stage products. It also covers the therapeutics assessment by product type, stage, route of administration, and molecule type. It further highlights the inactive pipeline products in this space.

Alpha-1 antitrypsin deficiency: Overview

Alpha-1 antitrypsin deficiency is an inherited disorder that may cause lung disease and liver disease. The signs and symptoms of the condition and the age at which they appear vary among individuals. Alpha1-antitrypsin is a protein made by the liver whose function is to protect the lungs. If these proteins are malformed or deficient, the impact is a predisposition for obstructive pulmonary disease and liver disease. This deficiency may predispose an individual to several illnesses and most commonly manifests as chronic obstructive pulmonary disease (including bronchiectasis) and liver disease (especially cirrhosis and hepatoma), or more rarely, as a skin condition called panniculitis. A deficiency of A1AT allows substances that break down proteins (so-called proteolytic enzymes) to attack various tissues of the body. The attack results in destructive changes in the lungs (emphysema) and may also affect the liver and skin.

The Main objectives of this report are:

• To analyze global Alpha-1 antitrypsin deficiency (AATD) status, future forecast, growth opportunity, key market and key players.
• To present the Alpha-1 antitrypsin deficiency (AATD) development in United States, Europe and China.
• To strategically profile the key players and comprehensively analyze their development plan and strategies.
• To define, describe and forecast the market by product type, market and key regions.

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The research includes historic data from 2015 to 2020 and forecasts until 2026 which makes the report’s an invaluable resource for industry executives, Marketing, Sales and product managers, consultants, analysts, and other people looking for key industry data in readily accessible documents with clearly presented tables and graphs.

Alpha-1 antitrypsin deficiency Emerging Drugs Chapters

This segment of the Alpha-1 antitrypsin deficiency report encloses its detailed analysis of various drugs in different stages of clinical development, including phase II, I, preclinical and Discovery. It also helps to understand clinical trial details, expressive pharmacological action, agreements and collaborations, and the latest news and press releases.

Alpha-1 antitrypsin deficiency Emerging Drugs

DCR-A1AT: Dicerna

DCR-A1AT is a subcutaneously administered ribonucleic acid interference (RNAi) therapeutic that is being investigated for the treatment of liver disease in patients with alpha-1 antitrypsin (A1AT) deficiency. DCR-A1AT, which incorporates Dicernas proprietary GalXC technology, is designed to target SERPINA1, reducing production of abnormal A1AT in the liver. A clinical trial program investigating the safety and efficacy of DCR-A1AT is currently underway. The U.S. Food and Drug Administration (FDA) has granted orphan drug designation (ODD) to Dicernas DCR-A1AT for the treatment of alpha-1 antitrypsin (A1AT) deficiency.

ARO-AAT: Arrowhead Pharmaceuticals

ARO-AAT is being developed to treat the liver disease associated with alpha-1 antitrypsin deficiency (AATD), a rare genetic disorder that severely damages the liver and lungs of affected individuals. ARO-AAT is designed to knock down the hepatic production of the mutant alpha-1 antitrypsin (Z-AAT) protein, the cause of progressive liver disease in AATD patients. Reducing production of the inflammatory Z-AAT protein is expected to halt the progression of liver disease and potentially allow it to regenerate and repair.

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Furthermore, this study will help to solve the following issues:

• Cyclical Dynamics-Report foresee dynamics of industries by using core analytical and unconventional market research approaches.
• Identifying key cannibalizes– Strong substitute of a product or service is the most prominent threat. Report includes key cannibalizes of a market, by procuring market research. This helps in aligning new product development/launch strategies in advance.
• Spotting emerging trends- Report helps to spot upcoming hot market trends. Report also track possible impact and disruptions which a market would witness by a particular emerging trend.
• Interrelated opportunities- This report will allow to make decisions based on data, thereby increasing the chances that the strategies will perform better.

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Note: All the reports that we list have been tracking the impact of COVID-19. Both upstream and downstream of the entire supply chain has been accounted for while doing this. Also, where possible, we will provide an additional COVID-19 update supplement/report to the report in Q3, please check for with the sales team.

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MarketInsightsReports provides syndicated market research on industry verticals including Healthcare, Information and Communication Technology (ICT), Technology and Media, Chemicals, Materials, Energy, Heavy Industry, etc. MarketInsightsReports provides global and regional market intelligence coverage, a 360-degree market view which includes statistical forecasts, competitive landscape, detailed segmentation, key trends, and strategic recommendations.

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