Cell-free Protein Expression Market Executive Summary, Introduction, Sizing, Analysis and Forecast To 2026 | Bioneer Corporation, Biotechrabbit Gmbh, Cellfree Sciences Co. Ltd, Cube Biotech Gmbh, Genecopoeia Inc., Jena Bioscience Gmbh

The cell-free protein expression market is expected to register a CAGR of 6.1% over the forecast period. Cell-free protein expression, or in vitro protein synthesis, is a process that involves the production of recombinant proteins in cell lysate solutions, without using cell culture or living cells. Cell-free protein expression can be carried out using different cell lysates, such as those of E. coli, rabbit reticulocytes, wheat germs, human cells, and insect cells. Increasing R&D in the field of proteomics and genomics and advantages offered by cell-free protein expression techniques, such as shorter expression time and structural modification, are contributing to the growth of the market. However, the lack of efficient systems for post-translational modifications and high costs could adversely affect market growth.

The report presents an in-depth assessment of the Global Cell-free Protein Expression including enabling technologies, key trends, market drivers, challenges, standardization, regulatory landscape, deployment models, operator case studies, opportunities, future roadmap, value chain, ecosystem player profiles and strategies. The report also presents forecasts for Global Cell-free Protein Expression investments from 2020 till 2025.

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Top Leading Manufactures-

Bioneer Corporation, Biotechrabbit Gmbh, Cellfree Sciences Co. Ltd, Cube Biotech Gmbh, Genecopoeia Inc., Jena Bioscience Gmbh, New England Biolabs Ltd, Promega Corporation, Qiagen Nv, Sigma-Aldrich Corporation (Merck Kgaa), Takara Bio Inc., And Thermo Fisher Scientific

Key Market Trends

Advantages, such as Shorter Expression Time and Structural Modification, are Contributing to Market Growth

Cell-free protein expression system has significant advantages over living-cell-based protein expression, including shorter duration of the process, isotopic labeling of proteins, the incorporation of non-natural amino acids, optimization of protein complexes, and cost-effectiveness. Furthermore, these techniques enable the manufacture of proteins that are toxic to host cells in the recombinant techniques. In vitro techniques also enable the co-expression of multiple proteins, and can easily be employed for automation, making high-throughput production of therapeutic proteins possible.
Other factors which are contributing to the market growth include increasing R&D in the field of proteomics and genomics and high prevalence of cancer and infectious disease

Lack of Efficient Systems for Post-Translational Modifications Is Limiting Market Growth

Despite significant advances in in vitro protein expression techniques, the lack of cost-effective and efficient systems for post-translational modifications remains a significant hurdle for the growth of the global market. E. coli lysates remain most commonly utilized in vitro protein expression systems, owing to their high protein yield and tolerability to additives. However, many of the eukaryotic proteins synthesized using E. coli lysate become insoluble upon expression, and post-translational modifications are also not possible. The inability of high yield systems to perform post-translational modifications, and human-cell-based systems low production yield could inhibit market growth, over the forecast period.
Other factors that could potentially impede the growth of the market include high costs of cell-free protein expression kits.

North America Dominates the Cell-free Protein Expression Market

In 2017, North America was the largest regional market in terms of revenue. The increasing prevalence of chronic diseases such as cancer, aging population, growing demand for targeted and personalized medicine, the presence of major R&D facilities, and favorable government initiatives are major factors contributing to the large market size

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Key Developments in the Cell-free Protein Expression Market

Aug 2018: LenioBio GmbH and Fraunhofer IME announced an exclusive license agreement for Fraunhofer's proprietary vector solution for the cryopreservation of cell lysates, and LenioBio GmbH revealed plans to launch its expression kit under the brand name ALiCE.

What are the market factors that are explained in the report?

–Key Strategic Developments: The study also includes the key strategic developments of the market, comprising R&D, new product launch, M&A, agreements, collaborations, partnerships, joint ventures, and regional growth of the leading competitors operating in the market on a Global and regional scale.

–Key Market Features: The report evaluated key market features, including revenue, price, capacity, capacity utilization rate, gross, production, production rate, consumption, import/export, supply/demand, cost, market share, CAGR, and gross margin. In addition, the study offers a comprehensive study of the key market dynamics and their latest trends, along with pertinent market segments and sub-segments.

–Analytical Tools: Global Cell-free Protein Expression Market report includes the accurately studied and assessed data of the key industry players and their scope in the market by means of a number of analytical tools. The analytical tools such as Porter’s five forces analysis, feasibility study, and investment return analysis have been used to analyzed the growth of the key players operating in the market. 

The research includes historic data from 2014 to 2020 and forecasts until 2025 which makes the reports an invaluable resource for industry executives, marketing, sales and product managers, consultants, analysts, and other people looking for key industry data in readily accessible documents with clearly presented tables and graphs.

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