Global Human Liver Model Market Size, Share, Analysis, Industry Report and Forecast to 2025

The global human liver model market is anticipated to grow at a substantial rate during the forecast period (2019-2025). The human liver model is a structure that assists in analyzing drug toxicity that may lead to liver failure or other liver diseases. The development of these models provides a better understanding of molecular interactions with network dynamics and the whole functioning of the internal organ. These innovative liver models are mini organs that replicate the physiology of the human liver from the molecular layer. This new area of science has the capability to replace animal models as the living models are more accurate and pose fewer ethical issues.

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Furthermore, researches are focused on the development of human liver models to determine the sensitivity of drugs for a large pool of a population. The global human liver model market is being driven by multiple factors that include the rising focus of pharmaceutical companies toward drug-induced liver injury treatment and increasing prevalence of Non-Alcoholic Fatty Liver Disease (NAFLD). Furthermore, a significant increase in research funding, a growing focus on developing alternatives for animal testing models and venture capital investments for the development of liver models are fueling market growth. However, there are certain restraints in the market that will hamper the growth that includes a lack of expert professionals in this field.

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The global human liver model market is divided on the basis of technology used in developing such models. These technologies include liver organoids, 3D bioprinting, 2D models, liver-on-a-chip and others. Furthermore, geographically, North America holds a significant position in the market owing to increasing government initiatives for the development of human liver models and increasing spending in the healthcare sector. Companies are introducing new products in order to stay competitive in the human liver model industry. For instance, in July 2019, Wacker (Munich) launched the first 3D printer for silicone elastomers that displays the inside of a human liver, indicating a tumor and other problems in this organ.

List of Key Companies in Human Liver Model Market

The major companies working in the market comprise InSphero AG, BioIVT, LLC, and Organovo Holdings, Inc. These companies are adopting several strategies, such as merger and acquisitions, product launches and collaboration and partnership to expand market share. For instance, in March 2018, BioIVT, LLC acquired Ascendance Biotechnology, which was established in 2015 from the merger of BioTime Inc.’s ESI BIO products division and Hepregen Corp. to develop a multinational cell-based assay firm. With this acquisition, BioIVT is including Hepregen’s HepatoMune, HepatoStem, and HepatoPac stem cell and liver cell product lines to its drug toxicology and drug safety testing portfolios. BioIVT has anticipated that widened use of highly functional Hepregen’s, in-vitro liver models would develop a significant understanding of the toxicity that results from long-term exposure to chemical compounds. This, in, turn, would support drug pre-clinical testing and other screening processes.

Current Market Trends Covered in the Market Report:

• Asia-Pacific - fastest-growing region during the forecast period
• Product Launch - a key strategy for the growth of the market
• Replacement of animal models with living models
• Increased research and development to increase the accuracy of human liver models

Global Human Liver Model Market Segmentation

By Technology

• Liver Organoids
• 3D Bioprinting
• 2D Models
• Liver-On-A-Chip
• Other

Global Human Liver Model Market by Region

North America

• US
• Canada

Europe

• Germany
• UK
• France
• Spain
• Italy
• Rest of Europe

Asia-Pacific

• China
• Japan
• India
• Rest of Asia-Pacific

Rest of the World

• Middle East & Africa
• Latin America

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