Single use Bioreactors Market to Grow at a CAGR of 21.9% | Opportunities and Challenges for New Market Entrants

In the current market scenario, there is a growing demand for single-use bioreactor products. The major factors driving the growth of the SUBs market include the increasing adoption of SUBs among small companies and startups, reduced automation complexity, ease in cultivating marine organisms, and reduced impact on the environment.

On the other hand, extractability and leachability issues regarding disposable components used in bioreactors and regulatory concerns related to SUBs are the major factors restraining the growth of this market.

The single-use bioreactors market is expected to reach USD 2,685.1 Million by 2022 from USD 818.3 Million in 2016 at a CAGR of 21.9%.

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Opportunity: Growing biologics market.

The biologics market is expected to witness a significant growth rate of 18% to 19% from 2014 to 2019. In the past decade, biologics have accounted for one-third of the total drugs approved by regulatory agencies. Growth in the biologics market is mainly driven by monoclonal antibodies and human insulin, which are among the leading contributors to the market. With this growth, the number of bioreactors needed for the R&D and manufacturing of biologics is also expected to increase in the coming years.

A new report published in 2014 by the Tufts Center for the Study of Drug Development (CSDD) estimated that the R&D investment needed for developing a new medicine is ~USD 2.6 billion. In this process, if disposable bioreactors are used instead of traditional bioreactors, the required investment can be reduced by 50%- 60%.

Challenge: Need for improved single use sensors.

The availability of dependable, accurate, and low-cost sensors that meet the needs of SUBs is one of the key challenges in the market. The sensors used in SUBs need to be compatible with the existing SUB platforms and are required to manage the system without affecting the sterility of materials. Traditionally, sensors were installed in SUB systems, but this practice lowered the quality of the final product.

Ideally, sensors and SUBs should be delivered as a single unit where the sensor is pre-installed in the SUB, which ensures sterilization of both containers and sensors. However, till date, the quality of sensors available is not as per the GMP standards because of leachability and extractability issues. This creates challenges while using SUBs and there is a scope for improvement in this segment of the market.

Europe is expected to account for the largest market share during the forecast period.

The single use bioreactor market has been segmented into four major regions, namely, North America, Europe, Asia Pacific, and the Rest of the World. In 2017, Europe is expected to account for the largest market share, followed by North America with a share of. The large share of Europe in this market is majorly attributed to the patent cliff of many biologic drugs in the region. As a result, several companies in Europe are engaged in research activities for the development of novel drug products. Moreover, governments in several European countries are supporting pharmaceutical companies to launch new biologic therapies that offer superior efficacy than traditional drugs. This, in turn, is increasing the number of R&D activities in the region.

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Leading Companies

Sartorius Stedim Biotech, Merck Millipore, GE Healthcare, Danaher, Thermo Fisher Scientific, Parker Hannifin, Applikon Biotechnology, Eppendorf, Cesco Bioengineering, Cellexus, Celltainer Biotech, PBS Biotech, Distek, Solida Biotech, Pierre Guerin

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