Advancements in Healthcare Improving Life Expectancy and Inadvertently Fueling Growth of the Bone Graft and Substitutes Market

The incorporation of a bone graft can be defined as a procedure of interdigitation and envelopment of the donor bone tissue with the new bone deposited by the recipient. It is a versatile that replaces the lost bone tissue, enhances bone growth using natural mechanisms. The natural bone graft are the most successful types of bone grafts and are considered to be the gold standard for replacement of missing bones. Bone grafts are in used in various purposes such as to fill the cavities resulting from cysts, tumors, or other causes, to stimulate the healing of fractures that have failed to heal after an initial treatment attempt, and others.

According to the Journal of Materials Science and Materials in Medicine, 2014, bone grafting frequency is the second most frequent tissue transplantation technique carried out globally after blood transfusion. The 2014 statistics reported in the Journal of Materials Science and Materials in Medicine, states that over 2 million bone grafting procedures are performed annually with over 500,000 graft implant procedures carried out in the U.S. itself. This is attributed to the ease of use and handling of new devices, improved safety profile, time advantages, intraoperative costs as well as the adaptability to a variety of clinical challenges.

The global bone graft, substitutes and membrane market is expected to witness a significant growth over the forecast period, owing to adoption of new technologies by manufacturers for development of innovative and novel bone graft substitutes. This includes the launches of novel growth factor enhanced grafts that improves the quality of grafts in terms of post-surgical recovery. For instance, in 2015, Cerapedics, a privately owned orthobiologics company received the U.S. FDA approval for i-Factor, which is a peptide enhanced graft that is used in cervical discectomy and fusion. The graft was based on small peptide (P-15) technology that helps in supporting bone growth through cell attachment and activation

Increasing number of regulatory approvals for a wide range of bone grafts and bone graft substitutes is expected to drive growth of the market over the forecast period. For instance, in April 2018, Medtronic Plc. received the approval from the U.S. Food and Drug Administration (FDA) to market two smaller kit sizes of INFUSE Bone Graft for usage in certain spinal fusion and dental regenerative procedures.

Approval helped the company to enhance their product portfolio. Moreover, In September, 2018, Baxter International Inc. received the U.S. Food and Drug Administration (FDA) clearance for ALTAPORE Bioactive Bone Graft, a next-generation bioactive and osteoconductive bone graft substitute, for using it as an autograft extender in posterolateral spinal fusion. Moreover, medical cases such as trauma and fractures including dislocations and life threatening musculoskeletal injuries can be treated with various types of bone grafts available in the market. Thus increasing number such medical cases is expected to drive the global bone graft and substitutes market growth over the forecast period.

For instance, trauma is a leading cause of death and disability in the U.S., according to the Centers for Disease Control and Prevention (CDC) 2014 report, for children and adults below age 45. Moreover, in the U.S. trauma accounts for around 79,000 deaths annually, in comparison to 15,000 infectious disease and 49,000 non-communicable disease deaths.

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