Schisandrin B: Ushering in a New Era in UV Protective Skincare

British Columbia, CA, September 12, 2011 -- Schisandrin B, a key component of GlissandrinTM, can protect against solar irradiation-induced oxidative injury in skin tissue and skin cells, according to recent research findings from the laboratory of Dr. Robert Ko at the Hong Kong University of Science and Technology.

As the largest organ in the human body, the skin serves as an effective barrier for protecting against various external threats. This includes exposure to harmful solar irradiation – particularly UV and infrared rays – which research has shown to be a major cause of skin aging. Solar irradiation-induced reactive oxygen species (ROS) generation is responsible for photo-aging, the signs of which include wrinkles, coarse skin texture, and reduced skin resilience. Although human skin tissue possesses non-enzymatic and enzymatic antioxidant defense systems to cope with the increased oxidative stress caused by solar light radiation, long-term exposure or over-exposure to solar light can overwhelm the antioxidant system.

But what if there was a way to enhance the skin’s natural antioxidant defenses to prevent photo-aging entirely? Schisandrin B (Sch B) is able to do just that, ushering in a new era in UV protective skincare.

Schisandrin B is derived from the Schisandra fruit, an herb commonly used in Traditional Chinese Medicine (TCM). This naturally occurring herbal ingredient has been found to produce tissue non-specific protection against oxidative injury by enhancing cellular and mitochondrial glutathione antioxidant status in the heart, liver, kidney, and brain.

Recent studies led by Dr. Robert Ko at the Hong Kong University of Science and Technology have shown the promise of Schisandrin B:

• Schisandrin B stimulated both reduced-glutathione and vitamin E levels. These two non-enzymatic antioxidants can remove excess ROS during oxidative stress in a synergistic manner.

• Schisandrin B elevated various enzymes involved in the enzymatic antioxidant defense system, demonstrating that non-enzymatic and enzymatic antioxidant components work together to protect against solar irradiation-induced oxidative injury in skin tissue.

• Schisandrin B suppressed the solar irradiation-induced increases in elastases-type protease activity and matrix-metalloproteinases-1 (MMP-1) expression in skin cells. The degradation of the extracellular matrix (EM) in skin tissue as a result of solar irradiation is of prime concern in skincare. This is one of the major biological events that leads to photo-aging and is mediated by protein-degrading enzymes like elastases-type protease and MMP-1.

Schisandrin B is a key component of Glissandrin™, a potent anti-aging skincare ingredient that has been the subject of over 100 research papers. In-vivo and in-vitro studies have proven the ability of Glissandrin to reverse mitochondrial decay, the leading cause of aging, and to simultaneously enhance the cell’s natural ability to fight oxidative damage.

Other studies have shown the ability of Schisandrin B to suppress collagenase, an enzyme responsible for the depletion of collagen in skin cells. Research has also been conducted on the compound’s anti-cancer properties, particularly in the skin.

Conclusion

Given that both spectra of solar light – UV and infrared radiation – are major causes of skin aging, Schisandrin B’s ability to enhance the skin’s antioxidant defenses against harmful solar irradiation, thereby offering the prospect of preventing skin photo-aging, is instigating a new era in skincare.

For more information
More information on Schisandrin B, mitochondrial decay, and theories of aging can be found at these independent websites:

• National Institutes of Health (http://www.nih.gov/)
• PubMed (http://www.ncbi.nlm.nih.gov/pubmed/)
• Natural Standard (http://www.naturalstandard.com/)

This article was contributed by Glissandra Skincare.

About Glissandra™
Glissandra Skincare Inc. is committed to providing effective anti-aging skincare through its holistic approach to skin health. Glissandra products are available through its dedicated team of independent distributors, using network marketing (also known as multi-level marketing, MLM, or direct sales). Glissandra’s compensation plan offers one of the most generous payouts in the industry.

Glissandra’s comprehensive skincare system is the result of almost 20 years of research and development at the Hong Kong University of Science and Technology, led by Professor Robert Ko. Over 100 research papers have been published on Glissandra’s key proprietary ingredient, Glissandrin™, a suite of natural compounds extracted from the Schisandra berry. In-vivo and in-vitro studies have proven the ability of Glissandrin to address mitochondrial decay, the leading cause of aging, and to enhance the cell’s natural ability to fight oxidative damage.

Contact:
Glissandra Skincare
Glissandra Skincare Inc
305-5811 Cooney Road
Richmond, BC
Canada V6X3M1
1-877-313-7242
info@glissandra.com
http://www.glissandra.com/

Schisandrin B, a key component of GlissandrinTM, can protect against solar irradiation-induced oxidative injury in skin tissue and skin cells, according to recent research findings from the laboratory of Dr. Robert Ko at the Hong Kong University of Science and Technology.

Glissandra Skincare
Glissandra Skincare Inc
305-5811 Cooney Road
Richmond, BC
Canada V6X3M1
1-877-313-7242
info@glissandra.com
http://www.glissandra.com/

This release was published on openPR.