Press release
P-CHECK® - Reliable Detection of Protease Contaminants
29.08.2011PANATecs has developed P-CHECK® - a test procedure for the detection of proteolytic enzymes in pharmaceutical and diagnostic raw materials and for in-process control in the production of therapeutic proteins. P-CHECK is currently only available as a service, but will also be sold as a complete kit from the end of the year.
Protein-based raw materials are often basic substances in diagnostic tests and are frequently contaminated with enzymes that break down proteins (proteases). Proteases can have unfavorable effects on the stability of test kit batches and falsify the results of measurements.
Proteases also present a problem in the production of biopharmaceuticals. They can destroy the product and are also a potential risk to patients, if they pass into the blood when the drug is injected.
P-CHECK® is based on the FRET technology (Fluorescence Resonance Energy Transfer). This test procedure guarantees maximal sensitivity for proteases down to the lower nanogram range. The scope is much greater than with previous tests and can be enormously expanded with a peptide library, covering up to 2.47 million sequence variants.
More information about P-CHECK® can be found at the Biotechnica from 11.-13.10.2011 in Hall 9/Stand D38, or at the BioPh from 25.-27.10.2011 in Hall 4.1./Stand 41B42.
PANATecs GmbH is a young and innovative service provider for the pharmaceutical, biotechnology and biotechnology industries. PANATecs employs high technology based on mass spectrometry to characterize the drugs of the future, which are to be used for the treatment of diseases which are difficult to cure. PANATecs has set itself the objective of becoming the market leader in service provision in protein analysis and will continue to expand its international business.
PANATecs is a spinoff from Tübingen University and celebrated its fifth birthday in 2009. Our highly qualified scientists and technicians, all with industrial experience, help us to support technological progress in the life sciences industry.
The company is certified according to ISO 9001 and holds the Manufacturing Authorization for Test Laboratories according to the German Medicines Act and Good Manufacturing Practice.
PANATecs GmbH
Vor dem kreuzberg 17
72070 Tübingen
Tel: +49 7071-92058-0
www.panatecs.com
info@panatecs.com
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