Natural Killer Cells Market to see Huge Growth by 2026| NantKwest, NKT Therapeutics Inc., AvidBiotics, Glycostem, Sorrento Therapeutics, Inc., CellGenix GmbH, Lonza and R&D Systems, Inc

Natural killer cells play an important role in stem-cell transplantation in therapies involving such cells activating endogenous natural killer cells and may transfer exogenous cells through adoptive cell therapy (ACT) and hematopoietic stem cell transplantation (HSCT). According to National Center for Biotechnology Information, U.S. National Library of Medicine, in 2014, such therapies are less effective in eliminating cancer stem cells as revealed by various studies.

Destructive midline facial lesions have conventionally been referred to as lethal midline granuloma. In some patients, the common causative lesions are Wegener’s granulomatosis, sarcoidosis, conventional Sino-nasal diffuse large B cell, and lymphomas carcinomas. However, among patients from Asia and South America, such lesions often show atypical lymphoid cells. This in turn is projected to favor the market growth in the near future.

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Furthermore, pro-inflammatory cytokines are secreted by activated natural killer cells, which then trigger Perforin/Granzyme induced target cell lysis. Their specific attaching ability and ability to discard stressed cells are fueling adoption of natural cells therapy, which is projected to support growth of the natural killer cells market over the forecast period.

Major players in the natural killer cells market are engaged in research and development process and offer a large product portfolio. For instance, R&D Systems offer a wide range of reagents for culturing natural killer cells and investigating natural killer cell and tumor cell interactions and various other components such as recombinant proteins, blocking/neutralization antibodies, fluorochrome-conjugated antibodies and ELISA Kits.

Major players in the market of natural killer cells include NantKwest, NKT Therapeutics Inc., AvidBiotics, Glycostem, Sorrento Therapeutics, Inc., CellGenix GmbH, Lonza and R&D Systems, Inc.

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Key players in the market are focused on various business strategies research and development, in order gain competitive edge in the market. For instance, in June 2019, NantKwest, a U.S.-based immunotherapy company, announced the U.S. Food and Drug Administration (FDA) clearance for the company’s PD-L1 t-haNK investigational new drug application (IND). The program is now transitioned to first-in-human clinical trial in patients with locally or advanced metastatic solid cancers.

Key players in the market are involved in various business strategies such as partnership and collaboration, in order provide novel products in the market. For instance, in March 2019, Phio Pharmaceuticals Corp., a U.S.-based pharmaceutical company, and Glycosystem Therapeutics BV, a Dutch biotech company, collaborated to explore potential synergies of using Phio’s self-delivering RNAi technology in combination with Glycosystem’s natural killer cell technology oNKord. This collaboration is done to develop cellular immunotherapies for cancer treatment.

Major companies in the global market are involved in growth strategies such as gaining grants from various institutes, in order develop novel products. For instance, in December 2018, Glycostem and Enpicom received a research subsidiary of undisclosed amount from the Dutch MIT Zuid research and development subsidy scheme. The companies are planning to use the funds to develop technology to predict the outcome of NK-Cell-based immunotherapy in patients with solid tumors.

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