Global Bone Graft and Substitutes Market Progresses for Huge Profits by 2026 With Top Players Stryker Corporation, Medtronic, DePuySynthes, Zimmer Biomet Holdings, NuVasive, Orthofix International N.V, Bone Therapeutics

Bone grafts and substitutes are the natural and synthetic products used by the surgeons to repair and reform bones in the spine, hips and knees through a medical procedure known as bone grafting. The bone used during grafting could be natural or synthetic. The most common types of bone grafts used are the autograft and allograft. An autograft comes from patients own body such as hips, pelvis and wrist. Allograft uses bone from deceased donor or a cadaver bone that has been cleaned and stored in the tissue banks. Bone graft substitutes are the synthetic or derived from allografts in varied forms.

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Synthetic bone grafts are made up of ceramics, composites, and polymer. Bone grafts substitutes are allografts based (Demineralized Bone Matrix), factor based such as transforming growth factor beta (TGF-beta), and platelet derived growth factor (PDGF), fibroblast growth factor (FGF), and bone morphogenetic proteins (BMP) and cell based bone grafts substitutes to generate new tissue alone or placed into support matrix (eg, mesenchymal stem cells). Bone graft and substitutes are primarily used because of fractures, fusion of two bones, bone and tissue regeneration and for bone healing with the implanted devices.

Market Dynamics

Bone grafts and substitutes market witnessed new product launches, partnerships and agreements in last few months. In October, 2017, DSM Biomedical signed a partnership agreement with a privately held orthobiologics company, Cerapedics to develop peptide enhanced bone graft. The strategic partnership will complement DSM’s material regeneration abilities with Cerapedics synthetic small peptide (P-15) technology. In April, 2017, BoneSupport AB extended its U.S distribution agreement with Zimmer Biomet for its Cerament bone void filler product.

According to the agreement Zimmer will have exclusive rights to distribute portfolio of bone void fillers for trauma, orthopedics and foot and ankle applications. In May, 2017, NovaBone introduced NovaBone IRM and IRM MacroPOR to its product portfolio. According to NovaBone, the products possess osteogenic and osteoblastic characteristics and are highly irrigation resistant. Increase in awareness of non-invasive technologies among the patients and shift towards derived forms of bone graft substitutes are also expected to favor the market in near future.

Major players operating the global bone graft and substitutes market include Ace Surgical Supply Co., Inc., NovaBone Product LLC, Medtronic Plc, Stryker Corporation, Zimmer Biomet Holdings, Inc., BioHorizons Implant Systems, Inc., Novadip Biosciences, Orthofix International N.V., Globus Medical, Inc., and Bone Therapeutics SA.

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Among geographical regions, North America contributes the maximum share in the bone grafts and substitutes market, owing to the increasing research and development activities in the field of bone grafting, which results in development of innovative bone grafts in the region. Asia Pacific is expected to gain significant traction, owing to the rise in medical tourism as well as development of novel bone graft substitutes by regional players, exhibiting equivalent efficiency at affordable prices.

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