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Global B-cell Maturation Antigen (BCMA) Targeted Therapies Market Revenue Growth Predicted by 2018-2026 With Top Players Celgene Corporation, GlaxoSmithKline , Novartis AG, Juno Therapeutics, Gilead Sciences, Amgen, Affimed N.V, Poseida Therapeutics

07-13-2019 10:59 AM CET | Health & Medicine

Press release from: Coherent Market Insights - Biotechnology

B-cell Maturation Antigen (BCMA) Targeted Therapies

B-cell Maturation Antigen (BCMA) Targeted Therapies

Recurrence of multiple myeloma has been a highly prevalent health condition, which requires novel and effective immunotherapeutic treatment. According to Leukemia Research by Elsevier, as of 2014, the incidence of multiple myeloma is estimated to be around 120,000 cases per year, with a global prevalence of over one million cases. B-cell maturation antigen (BCMA), is a cell surface protein that is expressed on the malignant plasma cells. This cell surface protein has emerged as a very selective antigen targeted therapy for the treatment of multiple myeloma. BCMA targeted therapies actively involve three major types of immunotherapies on the basis of product class namely, chimeric antigen receptor T-cells (CAR T Cells), bispecific antibodies, and antibody drug conjugates (ADCs). These advanced therapies are expected to improve the survival rate of multiple myeloma patients.

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Market Dynamics

Increasing prevalence of multiple myeloma is expected to favor the B-cell maturation antigen (BCMA) targeted therapies market worldwide. According to the American Cancer Society, U.S., in 2016, the lifetime risk for multiple myeloma was around 1 in 143 people, with an estimated 30,280 adults (17,490 men and 12,790 women) diagnosed with multiple myeloma. The mortality rate of the disease was estimated to be 12,590 (6,660 men and 5,930 women) in 2016. Key players are actively involved in the development of immunotherapies targeting BCMA for the treatment of multiple myeloma, the demand for which is expected to increase, This in turn, is expected to boost development of novel treatments for relapsed or refractory myeloma. Furthermore, patients undergoing existing drug therapies are prone to the risk of relapse. Hence, B-cell maturation antigen targeted therapy, which primarily addresses this concern is expected to gain rapid traction.

Increase in number of pipeline products are expected to boost growth of the B-cell maturation Antigen (BCMA) targeted therapies market

Market players are actively investing in research and development of novel multiple myeloma therapies to develop alternatives for existing drugs. These therapies includes chimeric antigen receptor T cells, antibody-drug conjugate, and Bi-specific antibodies. For instance, GlaxoSmithKline Plc. (GSK2857916) is developing the antibody drug conjugate drug with relapsed/refractory multiple myeloma and other advanced hematologic malignancies expressing BCMA. The robust pipeline therapies for treatment of multiple myeloma is expected to boost growth of the B-cell maturation Antigen (BCMA) targeted therapies market

Key players operating in the development of B-cell maturation antigen (BCMA) targeted therapies market are Celgene Corporation, GlaxoSmithKline plc, Novartis AG, Juno Therapeutics, Gilead Sciences. Inc., Amgen Inc., Affimed N.V, Poseida Therapeutics, Inc., and Autolus Ltd.

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Increase in number of pipeline products are expected to boost growth of the B-cell maturation Antigen (BCMA) targeted therapies market

Market players are actively investing in research and development of novel multiple myeloma therapies to develop alternatives for existing drugs. These therapies includes chimeric antigen receptor T cells, antibody-drug conjugate, and Bi-specific antibodies. For instance, GlaxoSmithKline Plc. (GSK2857916) is developing the antibody drug conjugate drug with relapsed/refractory multiple myeloma and other advanced hematologic malignancies expressing BCMA. The robust pipeline therapies for treatment of multiple myeloma is expected to boost growth of the B-cell maturation Antigen (BCMA) targeted therapies market.

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