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Isocitrate Dehydrogenase Inhibitors Market Size, Share, Development by 2024

06-28-2019 07:26 AM CET | Advertising, Media Consulting, Marketing Research

Press release from: Global Info Research

Isocitrate Dehydrogenase Inhibitors Market Size, Share,

Global Info Research offers a latest published report on Isocitrate Dehydrogenase Inhibitors Market Analysis and Forecast 2019-2025 delivering key insights and providing a competitive advantage to clients through a detailed report. This report focuses on the key global Isocitrate Dehydrogenase Inhibitors players, to define, describe and analyze the value, market share, market competition landscape, SWOT analysis and development plans in next few years.

To analyze the Isocitrate Dehydrogenase Inhibitors with respect to individual growth trends, future prospects, and their contribution to the total market.

To share detailed information about the key factors influencing the growth of the market (growth potential, opportunities, drivers, industry-specific challenges and risks).

Click to view the full report TOC, figure and tables:
https://www.globalinforesearch.com/global-isocitrate-dehydrogenase-inhibitors-market_p201566.html
 
Isocitrate dehydrogenase (IDH) (EC 1.1.1.42) and (EC 1.1.1.41) is an enzyme that catalyzes the oxidative decarboxylation of isocitrate, producing alpha-ketoglutarate (α-ketoglutarate) and CO2.

Scope of the Report:
Specific mutations in the isocitrate dehydrogenase gene IDH1 have been found in several brain tumors including astrocytoma, oligodendroglioma and glioblastoma multiforme, with mutations found in nearly all cases of secondary glioblastomas, which develop from lower-grade gliomas, but rarely in primary high-grade glioblastoma multiforme.Patients whose tumor had an IDH1 mutation had longer survival. Furthermore, mutations of IDH2 and IDH1 were found in up to 20% of cytogenetically normal acute myeloid leukemia (AML).These mutations are known to produce (D)-2-hydroxyglutarate from alpha-ketoglutarate.(D)-2-hydroxyglutarate accumulates to very high concentrations which inhibits the function of enzymes that are dependent on alpha-ketoglutarate.This leads to a hypermethylated state of DNA and histones, which results in different gene expression that can activate oncogenes and inactivate tumor-suppressor genes. Ultimately, this may lead to the types of cancer described above.Isocitrate dehydrogenase inhibition technology can be effectively applied to the cancer market.
The worldwide market for Isocitrate Dehydrogenase Inhibitors is expected to grow at a CAGR of roughly x% over the next five years, will reach x million US$ in 2024, from x million US$ in 2019, according to a new GIR (Global Info Research) study.
This report focuses on the Isocitrate Dehydrogenase Inhibitors in global market, especially in North America, Europe and Asia-Pacific, South America, Middle East and Africa. This report categorizes the market based on manufacturers, regions, type and application.

Market Segment by Manufacturers, this report covers
    AGIOS
    Aslan Pharmaceuticals
    Bayer
    Beigene
    Bristol-Myers Squibb
    Celgene
    Daiichi Sankyo
    Philogen S.p.A.
    Tesaro
    Tragara/Adastra
    Tocagen

Market Segment by Regions, regional analysis covers
    North America (United States, Canada and Mexico)
    Europe (Germany, France, UK, Russia and Italy)
    Asia-Pacific (China, Japan, Korea, India and Southeast Asia)
    South America (Brazil, Argentina, Colombia etc.)
    Middle East and Africa (Saudi Arabia, UAE, Egypt, Nigeria and South Africa)

Market Segment by Type, covers
    IDH1 Mutant Medullary Malignant Tumor
    IDH2 Mutant Medullary Malignant Tumor
    Others

Market Segment by Applications, can be divided into
    DH Inhibitor
    FLT3 Inhibitor
    Hedgehog Pathway Inhibitor
    Others

For More Information On This Report, Please Visit @
https://www.globalinforesearch.com/global-isocitrate-dehydrogenase-inhibitors-market_p201566.html

Related Information:
North America Isocitrate Dehydrogenase Inhibitors Market Growth 2019-2024
United States Isocitrate Dehydrogenase Inhibitors Market Growth 2019-2024
Asia-Pacific Isocitrate Dehydrogenase Inhibitors Market Growth 2019-2024
Europe Isocitrate Dehydrogenase Inhibitors Market Growth 2019-2024
EMEA Isocitrate Dehydrogenase Inhibitors Market Growth 2019-2024
Global Isocitrate Dehydrogenase Inhibitors Market Growth 2019-2024
China Isocitrate Dehydrogenase Inhibitors Market Growth 2019-2024

Customization Service of the Report :
Market Research Report Store provides customization of reports as per your need. This report can be personalized to meet your requirements. Get in touch with our sales team, who will guarantee you to get a report that suits your necessities.

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