Press release
Isocitrate Dehydrogenase Inhibitors Market Size, Share, Development by 2024
To analyze the Isocitrate Dehydrogenase Inhibitors with respect to individual growth trends, future prospects, and their contribution to the total market.
To share detailed information about the key factors influencing the growth of the market (growth potential, opportunities, drivers, industry-specific challenges and risks).
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https://www.globalinforesearch.com/global-isocitrate-dehydrogenase-inhibitors-market_p201566.html
Isocitrate dehydrogenase (IDH) (EC 1.1.1.42) and (EC 1.1.1.41) is an enzyme that catalyzes the oxidative decarboxylation of isocitrate, producing alpha-ketoglutarate (α-ketoglutarate) and CO2.
Scope of the Report:
Specific mutations in the isocitrate dehydrogenase gene IDH1 have been found in several brain tumors including astrocytoma, oligodendroglioma and glioblastoma multiforme, with mutations found in nearly all cases of secondary glioblastomas, which develop from lower-grade gliomas, but rarely in primary high-grade glioblastoma multiforme.Patients whose tumor had an IDH1 mutation had longer survival. Furthermore, mutations of IDH2 and IDH1 were found in up to 20% of cytogenetically normal acute myeloid leukemia (AML).These mutations are known to produce (D)-2-hydroxyglutarate from alpha-ketoglutarate.(D)-2-hydroxyglutarate accumulates to very high concentrations which inhibits the function of enzymes that are dependent on alpha-ketoglutarate.This leads to a hypermethylated state of DNA and histones, which results in different gene expression that can activate oncogenes and inactivate tumor-suppressor genes. Ultimately, this may lead to the types of cancer described above.Isocitrate dehydrogenase inhibition technology can be effectively applied to the cancer market.
The worldwide market for Isocitrate Dehydrogenase Inhibitors is expected to grow at a CAGR of roughly x% over the next five years, will reach x million US$ in 2024, from x million US$ in 2019, according to a new GIR (Global Info Research) study.
This report focuses on the Isocitrate Dehydrogenase Inhibitors in global market, especially in North America, Europe and Asia-Pacific, South America, Middle East and Africa. This report categorizes the market based on manufacturers, regions, type and application.
Market Segment by Manufacturers, this report covers
AGIOS
Aslan Pharmaceuticals
Bayer
Beigene
Bristol-Myers Squibb
Celgene
Daiichi Sankyo
Philogen S.p.A.
Tesaro
Tragara/Adastra
Tocagen
Market Segment by Regions, regional analysis covers
North America (United States, Canada and Mexico)
Europe (Germany, France, UK, Russia and Italy)
Asia-Pacific (China, Japan, Korea, India and Southeast Asia)
South America (Brazil, Argentina, Colombia etc.)
Middle East and Africa (Saudi Arabia, UAE, Egypt, Nigeria and South Africa)
Market Segment by Type, covers
IDH1 Mutant Medullary Malignant Tumor
IDH2 Mutant Medullary Malignant Tumor
Others
Market Segment by Applications, can be divided into
DH Inhibitor
FLT3 Inhibitor
Hedgehog Pathway Inhibitor
Others
For More Information On This Report, Please Visit @
https://www.globalinforesearch.com/global-isocitrate-dehydrogenase-inhibitors-market_p201566.html
Related Information:
North America Isocitrate Dehydrogenase Inhibitors Market Growth 2019-2024
United States Isocitrate Dehydrogenase Inhibitors Market Growth 2019-2024
Asia-Pacific Isocitrate Dehydrogenase Inhibitors Market Growth 2019-2024
Europe Isocitrate Dehydrogenase Inhibitors Market Growth 2019-2024
EMEA Isocitrate Dehydrogenase Inhibitors Market Growth 2019-2024
Global Isocitrate Dehydrogenase Inhibitors Market Growth 2019-2024
China Isocitrate Dehydrogenase Inhibitors Market Growth 2019-2024
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