Monoclonal Antibody Diagnostic Reagents Market Dynamics 2019 By Key Pkayers: AnaSpec, BioGenex, Bio-Rad, Biocare Medical, BioVision, Celltrion, Creative Diagnostics, GenWay Biotech, Innovent Biologics
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Non-infectious diseases are the leading cause of mortality and morbidity worldwide. As per the WHO 2017 data, around 40 million individuals suffering from cardiovascular diseases, cancer, chronic respiratory diseases, diabetes, and stroke die every year across the globe. Prevailing cancer incidence rate are expected to fuel demand for disease diagnosis. According to International Agency for Research on Cancer (IARC), the incidence of cancer is expected to reach to 26.8 million new cases and 17.1 million deaths annually by the year 2030.
Monoclonal antibodies are effective biological reagents in immunodiagnostic assays due to their binding accuracy to many pathogens, thereby, making it an important research tool. Despite many advantages and applications offered by monoclonal antibodies, it is difficult to get the right antibodies and attach a compound to it. Monoclonal antibodies need considerable amount of time, money, and manpower to produce them which can hinder the market size to some extent.
Diagnostic tests based on the use of MAbs as reagents are routinely used in enzyme-linked immunosorbent assays and radioimmunoassay in laboratories. These tests measure the circulating concentrations of hormones (gastrin, growth hormone, human chorionic gonadotropin, insulin, progesterone, thyroid stimulating hormone, thyroxine, triiodothyronine, and renin) and cell products (blood clotting factors, blood group antigens, histocompatibility antigens, interferon, interleukins, and tumor markers).
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Monoclonal antibodies play a valuable role in diagnostic medicine during tests to determine the concentration of specific proteins in blood or urine. For instance, high blood level of a prostate-specific antigen, measured by its interaction with a monoclonal antibody, provides an early warning for prostate cancer. Antibodies to target biomarkers are widely used for detecting carcinogenic-embryonic antigen (colorectal cancer), prostate specific antigen (expressed in prostate cancer), CA125 (ovarian cancer), CA19-9 (gastrointestinal cancer), CA15-3 antigen, and HER-2/neu proteins (breast cancer).
Asia Pacific monoclonal antibody diagnostic reagents market is expected to exhibit the highest growth rate, due to rising incidence of lifestyle-induced diseases coupled with rising population base demanding disease diagnosis. According to WHO data, non-communicable diseases deaths are projected to increase by 15% between 2010 and 2020, with the highest numbers predicted in the Western Pacific (12.3 million deaths) and South-East Asia (10.4 million deaths) regions.
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Key players operating in the monoclonal antibody diagnostic reagents market include AnaSpec, BioGenex, Bio-Rad, Biocare Medical, BioVision, Celltrion, Creative Diagnostics, GenWay Biotech, Innovent Biologics, Medix Biochemica, Qiagen, and Teva Pharmaceutical Ltd.
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