Bone Glue Market To Reflect Significant Incremental Opportunity During 2018-2026 With Top Manufacturers Cryolife, Luna Innovations Incorporated, Johnson and Johnson, Cohera Medical Inc., Tissuemed Ltd

Bone glues are a collagen obtained from an animal base that mainly includes skin and bones. Bone glues are derivative of fish’s dehydrated bladder and dense bone. The production process of bone glue is complicated, which involves obtaining animal bones from various abattoirs, meat packaging companies, and tanneries. The bones are cleaned and washed set for under pressure to boil to demineralize it and then collagen is extracted and dried. The most used commercial area apart from healthcare industry is in manuscript publishing, carpentry, and gun powder production applications.

The bone glues market is expected to gain steady traction in the foreseeable future as the product finds application across a wide number of industries. Manufacturers are focused on reducing production costs and increasing profitability by developing multipurpose bone glues. The global bone glue market was valued at US$ 1,648.3 million in 2015 and is expected to witness a CAGR of 6.3% during the forecast period (2016 – 2024).

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Market Dynamics

The growing incidence of bone associated disorders is a key factor fueling growth of the global bone glue market. Approximately 1.5 million bone splintering cases lead to over half a million hospitalizations in the U.S. each year. Hip fractures is one of the prevalent of bone fractures, resulting in over 300 thousand hospitalizations annually. Apart from general bone fracture, procedures related to bone, such as arthroplasty and rising demand for advanced bone glues in North America and Europe are factors projected to fuel growth of the global market over the forecast period. Product portfolio expansion and development of new products that can heal the bone crack, are some of the other factors augmenting growth of the global bone glue market. Complex regulatory process and limited therapeutic applications of wound care products are impeding growth of the global bone glue market.

Naturally produced bone glue from animals hits the bone glue market

The growing prevalence of bone disorders and ageing population are the important aspects for the significant growth in bone glue market in Europe. Growing number of arthroplasty procedures and the consequent rise in demand for newer bone glues across various countries in Europe would further fuel growth of bone glue market in the region. However, stringent regulations in US such as, institutions and universities who use animals for research purpose should be licensed and or registered with the U.S. Department of Agriculture and facilities, regulated animals must be inspected yearly by USDA’s Animal and Plant Health Inspection Service, has hit the bone glue market by inhibiting the production of natural glue obtained from animals.

Non-animal substitutes i.e. synthetic glue are relatively more expensive and can also lead to compatibility issues. Difficulties such as the irritation caused by the cement to the surrounding skin, over prolong application, breakdown of the cement can cause the artificial joint to come loose, breakage of cement in bits are associated with cemented arthroplasty is the one of the main concerns which hamper the growth of the bone glue market.

Competitive Analysis

Key companies covered as a part of this study include Cryolife, Luna Innovations Incorporated, Johnson and Johnson, Cohera Medical Inc., Tissuemed Ltd., Integra Lifesciences Corporation, Baxter International Inc., B.Braun Melsungen AG, DENTSPLY SIRONA Inc., Chemence Medical Inc. and C.R. Bard Inc.

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Bone cement implantation syndrome is most prominent in patients undergoing hip fracture treatment

Bone glue is a basic product needed in any minor fractures and also act as beneficial supplements for musculoskeletal tissue suture repair. There are various other options such as bone cement and bone surgery to treat multiple fractures. A study was conducted by various medical institutes and university hospitals in 2014, with a patient pool of around 1,016 patients who underwent cemented hemiarthroplasty at some point in their life. A common symptom called bone cement implantation syndrome was observed in people suffering from hip fractures and the incidence rate was reported to be between 25% and 30%.

Severe bone cement implantation syndrome was observed in 5–7% of patients in the study group. Independent preoperative threat issues for occurrence of bone cement implantation syndrome were irregularities in overall health conducted by the universities, i.e. ASA scores, COPD, and medication with diuretics and warfarin. In cemented total hip arthroplasty, fatalities were pegged at 0.11% and the death occurred during the time of cementation. Considering all these factors, companies have developed bone glue products. The increased usage of bone glue in such cases would boost growth of the bone glue market.

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