Enzyme Linked Immunosorbent Assay Market Competitive Status and Major Players Bio-Rad Laboratories,Enzo Life Sciences, Thermo Fisher Scientific,Biomerieux

Enzyme Linked Immunosorbent Assay (ELISA) is immunoassay used to identify proteins, peptides, antibodies, and hormones. ELISA assay has application in biotechnology medicine, as a diagnostic tool, which detects color change to identify a target substance and measures its concentration in the test sample. The common diagnostic applications of ELISA are HIV infection, pregnancy tests, and measurement of cytokines, soluble proteins, and others. Various antigen-antibody combinations are used in the immunoassay that include an enzyme-labeled antigen or antibody and enzyme activity is measured.

On the basis of antigen-antibody combination, the assay is segmented in to direct ELISA, indirect ELISA, sandwich ELISA, and competitive ELISA. Increasing prevalence of infectious disease such as HIV and increasing awareness regarding diagnosis of cancer and autoimmune diseases are major factors propelling demand for ELISA to reduce the burden of chronic diseases with early and accurate disease diagnosis. For instance, According to Centers of Disease Control & Prevention (CDC), 2014, number of patients infected with HIV in the U.S. was 37,600. The CDC also reported a decline of 10% in the incidence rate of HIV as compared to 2010, owing to early detection and advanced diagnostic.

The global Enzyme Linked Immunosorbent Assay (ELISA) Market was valued at US$ 1,583.4 million in 2017 and is expected to witness a robust CAGR of 5.1% over the forecast period (2017 - 2025).

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Moreover, advancements in the technology of ELISA are also fueling the market growth. For instance, in August 2017, researchers at University of Illinois, Urbana Campaign, developed a portable spectral analyzer based on ELISA assay that enables a smartphone to perform lab grade medical diagnostic tests, which usually requires expensive instruments. This test includes detection and measurement of variety of proteins and antibodies in blood, urine, and saliva samples that is commonly used for wide range of clinical diagnostic tests. Apart from the conventional medical applications such as disease diagnosis and transplantation, ELISA can also be used in the field of toxicology for determination of certain classes of drugs that is expected to aid the market growth in near future. However, cross reactivity leading to false positive and false negative results exhibited by the tests leading to incorrect diagnosis can obstruct the market growth. For instance, according to study report published by American Medical Association 2011, the preliminary health department data identified 32 pregnant women with HIV positive through ELISA assays. However, after a confirmatory test, 17 of these women were confirmed to be negative for HIV virus.

In terms of region, North America dominated the global Enzyme Linked Immunosorbent Assay (ELISA) Market. This is attributed to development of innovative products by manufacturers in the region. For instance, in January 2018, Eagle Biosciences, Inc. introduced a novel intact FGF23 ELISA kit assay, which is a 96 well Sandwich ELISA assay. It measures the full length active form of Human Intact FGF23 used for the detection of Mineral Bone Disorder, Chronic Kidney Disease, Tumor induced Osteomalacia, and hyperphosphatemia. Moreover, various private and public sectors carrying out research and development in Immunoassay-based clinical diagnostics are commercializing their research inventions by collaborating with existing market players to introduce new products in the market. For instance, in March 2018, BARD1 Life Sciences, U.S-based Science Research Company is expected to commercialize its BARD1-Ovarian blood based ELISA test to identify ovarian cancer in early stages. Furthermore, Asia Pacific is projected to be the fastest growing region in ELISA market, owing to geographical expansion of regional players along with introduction of novel enzyme-based test kits at affordable prices. For instance, in January 2017, Fujirebio, a Japan-based IVD diagnostic testing company introduced Lumipulse G β-Amyloid 1-42 ELISA assay in Europe that facilitates quantitative measurement of β-amyloid1-42 in human cerebrospinal fluid within of 30 minutes.

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This release was published on openPR.