openPR Logo
Press release

Nimbus Discovery and Proteros enter into multi-target X-ray protein crystallography collaboration

03-23-2011 05:44 PM CET | Science & Education

Press release from: Proteros biostructures GmbH

/ PR Agency: BCNP Consultants GmbH
Martinsried, Germany, March 23, 2011. Proteros Biostructures GmbH (“Proteros”) announced today that it has entered into a strategic collaboration with Nimbus Discovery, LLC (“Nimbus”) to deliver X-ray protein crystal structures for multiple targets.

Under the agreement, Proteros will provide structures from its Gallery Structure list, an ever growing catalogue of ready-to-use proteins (currently over one hundred) for rapid X-ray structure analysis of protein-ligand complexes in addition to providing gene-to-structure projects for novel biological targets. Proteros will deploy its high throughput crystallography platform and proprietary technologies to provide Nimbus with rapid turnaround in support of their discovery projects. Proteros will also generate customized structures for Nimbus’ proprietary programs and clinical candidates.

Proteros has no internal drug discovery programs and continues to focus and invest in developing its service business which consists of X-ray protein crystallography, kinetic and thermodynamic compound profiling and integrated lead discovery based on a fragment library of over 30,000 novel target directed molecules.

Cony D’Cruz, CBO and President of Proteros (US) Inc. said: “We are delighted to be working with an innovative company such as Nimbus. We look forward to using our proven expertise in crystallography to assist with Nimbus’ exciting discovery goals.”

”Our collaboration with Proteros Biostructures generates real-time structural data to accelerate our programs against fundamental disease targets”, added Jonathan Montagu, Vice President, Business Operations at Nimbus. ”Proteros is a key component of our virtually integrated, globally distributed R&D model”.

About Nimbus Discovery:
Nimbus Discovery is applying advances in computer-based drug discovery to develop new medicines against important drug targets and thereby unlock fundamental biological pathways. Nimbus has established a first-of-its-kind partnership with Schrödinger, the leader in computational drug discovery, to gain privileged access to cutting-edge technology and exclusive rights to key targets. Nimbus has already delivered selective, potent, and differentiated compounds within the first year for two disease targets that are pivotal in the progression of an aggressive form of Non-Hodgkin’s lymphoma and obesity, respectively. Nimbus has built a virtually integrated, globally distributed R&D organization that leverages an experienced internal drug discovery team across an external network of R&D partners. The resulting organization is scalable, capital efficient and has attracted world-class talent. Nimbus seeks to partner its programs with larger pharmaceutical companies early in the development process allowing Nimbus to focus on its competitive advantage in novel drug discovery. Nimbus programs are held in target-specific subsidiaries under an LLC umbrella. Nimbus Discovery was founded in 2009 by Atlas Venture and Schrödinger, Inc. In 2010, Nimbus received three Qualifying Therapeutic Discovery Project Tax Credit (QTDP) grants for its programs. For more information please visit www.nimbusdiscovery.com.

About Proteros biostructures GmbH:
Proteros is a privately held company that provides services and proprietary technologies to support integrated drug discovery. Proteros uses its technical expertise, industrial processes and unique technologies for crystallography, kinetic and thermodynamic profiling and fragment-based lead generation incorporating protein structure inspired compound and fragment libraries. The platform enables ‘knowledge driven lead engineering’ to accelerate and improve protein structure analysis and structure-based drug discovery. Proteros complements its clients’ internal capabilities with external expertise and access to flexible resources. Proteros currently provides services to more than 80 pharmaceutical and biotechnology clients in North America, Europe and Japan. Proteros US, Inc. is a wholly owned subsidiary of Proteros established to serve the growing customer base in North America.

Proteros biostructures GmbH
Kurt Herrenknecht, Ph.D.
Am Klopferspitz 19
82152 Martinsried
Germany
Phone: +49 (0) 89 7007 61 - 0
Fax: +49 (0) 89 7007 61 - 15
E-Mail: herrenknecht@proteros.com
Web: www.proteros.com

Nimbus Discovery, LLC
Jonathan Montagu
Vice President, Business Operations
25 First Street, Suite 303
Cambridge, MA 02141
USA
Phone: + 1 (617) 588-2600
Fax: +1 (617) 231-0652
Email: info@nimbusdiscovery.com
Web: www.nimbusdiscovery.com

This release was published on openPR.

Permanent link to this press release:

Copy
Please set a link in the press area of your homepage to this press release on openPR. openPR disclaims liability for any content contained in this release.

You can edit or delete your press release Nimbus Discovery and Proteros enter into multi-target X-ray protein crystallography collaboration here

News-ID: 167789 • Views: 1642

More Releases from Proteros biostructures GmbH

PROTEROS ANNOUNCES SUCCESSFUL CLOSE OF FINANCING ROUND
Largest-ever Financing allows for Expansion of Drug Discovery Capabilities MARTINSRIED, GERMANY (August 6th, 2012) – Proteros biostructures GmbH (‘Proteros’) announced today that it had successfully closed a financing round of five million Euros to fund the continued expansion and growth of the company. The financing round was led by BayBG, a key equity investor for Proteros. The financing round is the third and largest investment into the firm since the inception
Proteros and Eisai Co., Ltd enter into Integrated Lead Discovery Collaboration
Martinsried (Germany), April 16, 2012. Proteros biostructures GmbH today announced that the company has entered into a research collaboration with Eisai Co., Ltd (Japan) to identify small molecule inhibitors against a target selected by Eisai in the field of immunology. Under the agreement Proteros will deliver a novel lead compound applying its integrated lead discovery platform that includes X-Ray structural biology, biophysical screening and profiling, novel fragment libraries and medicinal chemistry
Proteros announces the appointment of Dr. Klaus Hinterding as Chief Scientific O …
Martinsried, Germany, February 9, 2012. Proteros biostructures GmbH (Proteros) announced today that Dr. Klaus Hinterding, formerly at Hoffmann-La Roche Ltd. (Roche), has joined the company as Chief Scientific Officer and member of the management board. Dr. Hinterding brings to Proteros considerable pharmaceutical industry experience that spans early research through to clinical development in various therapeutic areas. At Novartis, his research contributed to the understanding of the mode-of-action of GilenyaTM, licensed for
Janssen Pharmaceutica NV and Proteros expand relationship and enter into Global …
Martinsried Jan 09, 2012. Janssen Research & Development, a division of Janssen Pharmaceutica NV (“Janssen”) and Proteros biostructures GmbH (“Proteros”) today announced they have entered into a long-term global service agreement granting Janssen privileged access to Proteros portfolio of discovery technologies and services. Under the agreement Janssen will have broad access to Proteros’ drug discovery technologies, including structural biology, biophysical screening and profiling service, novel fragment libraries, medicinal chemistry expertise and

All 5 Releases


More Releases for Nimbus

Cloud Directory Services Market Will Hit Big Revenues In Future | Microsoft, Ora …
Latest released the research study on Global Cloud Directory Services Market, offers a detailed overview of the factors influencing the global business scope. Cloud Directory Services Market research report shows the latest market insights, current situation analysis with upcoming trends and breakdown of the products and services. The report provides key statistics on the market status, size, share, growth factors of the Cloud Directory Services. The study covers emerging player’s
Enterprise Flash Storage Market to Set Phenomenal Growth| Virident Systems, Nimb …
HTF MI recently introduced Global Enterprise Flash Storage Market study with in-depth overview, describing about the Product / Industry Scope and elaborates market outlook and status to 2023. The market Study is segmented by key regions which is accelerating the marketization. At present, the market is developing its presence and some of the key players from the complete study are Pure Storage Inc., Virident Systems, Inc., Violin Memory Inc., Oracle
Global Powerboats Market 2018 - Nor-Tech, BAVARIA Yachts, Nimbus Powerboats, Fou …
Apex Market Reports, recently published a detailed market research study focused on the “Powerboats Market” across the global, regional and country level. The report provides 360° analysis of “Powerboats Market” from view of manufacturers, regions, product types and end industries. The research report analyses and provides the historical data along with current performance of the global PP Pipe industry, and estimates the future trend of Powerboats on the basis of
Global Diesel Powerboats Market 2017 - Velocity Powerboats, Nor-Tech, BAVARIA Ya …
In this report, the global Diesel Powerboats market is valued at USD XX million in 2016 and is expected to reach USD XX million by the end of 2022, growing at a CAGR of XX% between 2016 and 2022. Geographically, this report is segmented into several key Regions, with production, consumption, revenue (million USD), market share and growth rate of Diesel Powerboats in these regions, from 2012 to 2022 (forecast), covering -
Global Reverse Osmosis Water Treatment Equipment Market 2017 - AMI, Watts, KMS, …
Apex Market Reports, recently published a detailed market research study focused on the "Reverse Osmosis Water Treatment Equipment Market" across the global, regional and country level. The report provides 360° analysis of "Reverse Osmosis Water Treatment Equipment Market" from view of manufacturers, regions, product types and end industries. The research report analyses and provides the historical data along with current performance of the global Reverse Osmosis Water Treatment Equipment industry,
Global Power Boats Market 2017 - Nor-Tech, Velocity Powerboats, BAVARIA Yachts, …
The Report describe Power Boats Introduction, product scope, market overview, opportunities, risk, driving force also to analyze the top manufacturers, with sales, revenue, and price, market type and application, with sales market share and growth rate by type, application, from 2017 to 2022 The Global Power Boats Industry report delivers en executive-level blueprint of the Power Boats market that will help clients to build strategies to expand their market operations. The