Immune Anti-Inhibitor Market In-depth Study On Shire Plc, Baxter International, Inc, F. Hoffmann La Roche Ltd., Novo Nordisk A/S

According to Centers for Disease Control and Prevention (CDC), 2016, an estimated 1 in 5 people with haemophilia A and about 3 in 100 people with haemophilia B develop inhibitors (antibodies). Moreover, patients suffering from Von Willebrand Disease (VWD) type 3 are also at a risk of developing inhibitors. According to National Haemophilia Foundation (NHF), haemophilia A occurs in 1 in 5,000 people and is four times as common as haemophilia B, which supports growth of the immune anti-inhibitors market. Ongoing research and development of different therapies for haemophilia with inhibitors are expected to boost growth of the global immune anti-inhibitor market.

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Moreover, the Center for Disease Control and Prevention (CDC) is examining the etiology of the haemophilia with inhibitors, which could help in development of novel therapies to boost growth of the immune anti-inhibitor market. Pipeline for haemophilia with inhibitors is also promising as few of the manufacturers are working on novel therapies for the condition. One such organization Catalyst Biosciences has a Factor VIIa marzeptacog alfa (activated) in the clinical trials for haemophilia A or B with inhibitors. Moreover, Bioverativ Inc., a Sanofi S. A.'s subsidiary has FVIIIa mimetic bispecific antibody under studies for haemophilia A with inhibitors.

Researchers are working on analyzing the risks associated with use of replacement factors, as in which replacement factors are more prone to facilitate development of antibodies. For instance, World Federation of Haemophilia (WFH) announced results from study published in journal ‘Blood’ in 2014, which demonstrated higher incidence of inhibitor development after treatment with Kogenate FS/Bayer/Helixate NexGen replacement factor.

The World Federation of Haemophilia has requested the U.S. Food & Drug Administration and the European Medicine Agency (EMA) to examine the data. Such studies are expected to reduce the instances of haemophilia with antibodies. Furthermore, therapies such as Immune Tolerance Induction (ITI) which involve continuous treatment with replacement factors till they are no longer considered as foreign bodies by inhibitors are expected to restrain the growth of the market.

Key players operating in global immune anti-inhibitor market include Shire Plc, Baxter International, Inc, F. Hoffmann La Roche Ltd., Novo Nordisk A/S, and CSL Behring.

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Immune Anti-Inhibitor Market Taxonomy-

The global immune anti-inhibitor market is segmented on the basis of product type, distribution channel, and geography.

By Product Type-

Recombinant
Plasma-Derived
Others
By Distribution Channel-

Hospital Pharmacies
Online Pharmacies
Retail Pharmacies
By Geography-

North America
Europe
Asia Pacific
Latin America
Middle East
Africa

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