Single Cell Analysis Market Growth Opportunities and Forecast Till 2026 Including Global Top Key Players Becton, Dickinson and Company, GE Healthcare, Illumina, Bruker, Agilent Technologies, Bio-Rad Laboratories, Inc., Danaher Corporation

Single cell analysis is an emerging technology that helps sequence whole human genome at a single cell level. This particularly includes genomics, transcriptomics, proteomics, epigenomics, and metabolomics with its sensitivity improved to single cell level. In genomics, new generation methodologies such as next generation sequencing and third generation sequencing play crucial roles. The aim of single cell analysis is mainly to measure and analyze cellular heterogeneity. Single cell analysis interpret life at fundamental level and find immense applications in the field of medicine. Single cell analysis over conventional standard cell numbers sequencing method enable the discovery and investigation of unknown micro-organisms.

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A study published in the Journal of Single Cell Analysis 2014, stated that a variety of technologies that are powerful and less expensive, such as Multiple Annealing And Looping-Based Amplification Cycle (MALBAC) and Multiple Displacement Amplification (MDA), find great progress in uncovering somatic mutations in human genome and detection of copy number variation. But in human single-cell genomics, Whole Genome Sequencing or Whole Exome-Sequencing (WGS or WESseq) finds great potential in clinical applications, especially in screening, diagnosis, and monitoring. It is popular in academic research because mRNA helps bridge genome structure and epigenomics modification with phenotype, reveals gene functions and regulatory network, and most importantly it is easier to perform than proteomics.

Inclination toward single-cell technology by biologists is mainly because many samples including stem cells, immune cells, neurons, cancers, and other tissues exhibit a stochastic nature with heterogeneity factor. Conventional methods cannot provide transcriptomic profile in highly heterogeneous cell population. Even if cell population is less, single cell analysis can enable the identification of biomarkers of delicate phenotypes or disorders (e.g. cancer stem cells). In addition, this analytical technique also helps classify different cell types in different physiological and pathological conditions, in very rare events of any somatic mutation, epigenetic modification of regulatory gene expression, and its function.

Global Single Cell Analysis Market – Trends and Opportunity

A study by the Journal of Analytical and Bioanalytical Chemistry in 2014, stated that Inductively Coupled Plasma Mass Spectroscopy (ICP-MS) and ICP Optical Emission Spectrometry (ICP-OES) are applied using metal atoms such as nanoparticle for investigation of cell-to-cell variance or cellular uptake of drugs and other elements. Single-cell genomics find many clinical applications such as genetic diagnosis of embryo-related diseases and to study blood-borne Circulating Tumor Cells (CTCs). These applications may be further employed for diagnosis, prognosis, and treatment of cancer.

Major key players in the global single cell analysis market include

1. 10X Genomics
2. Abcam Plc.
3. Agilent Technologies
4. Fluxion Biosciences
5. Becton
6. Dickinson and Company
7. Bio-Rad Laboratories, Inc.
8. Bio-Techne Corporation
9. Bruker
10. Danaher Corporation
11. Fluidigm Corporation
12. GE Healthcare
13. Illumina

among others....

Global Single Cell Analysis Market Taxonomy

The global single cell analysis market is segmented on the basis of product, types of cells, type of technique, application, and end user.

By product:

Consumables (beads, microplate, reagents, assay kits, etc.)
Instruments (PCR, NGS system, spectrophotometers, etc.) - Automated, Manual

10x Genomics, in 2017, launched the chromium single cell V(D)J solution for profiling full length paired V(D)J transcripts from hundreds to millions of lymphocyte. It is a reagent system, which has the ability to completely identify and characterize T and B cells by single cell sequencing. This will reveal true clonality and diversity in adaptive immune system. This product will have an impact on research based single cell analysis market.

By Types of cells: Human, Animal, Microbial
By Type of technique: Mass Spectroscopy (MS), Polymerase Chain Reaction (PCR), Next-Generation Sequencing, Flow Cytometry, Microscopy
By Application: Research, Diagnostic applications, Noninvasive Prenatal Diagnosis (NIPD), In Vitro Fertilization (IVF), Circulating Tumor Cells (CTCs)
By End User: Academic & Research Institutes, Biotechnology and Biopharmaceutical Companies, Hospitals and Diagnostic Laboratories, Cell Banks and IVF Centers

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Also, Coherent Market Insights has a proprietary database of pipeline biologics and biosimilars, called PHASE-XS. This database provides analytical data in addition to the clinical information of ongoing trials for biologics and biosimilars. An amalgamation of more than 30 parameters, PHASE-XS helps biotechnology and pharmaceutical companies to analyze the market trend, competition, and market potential. For more information or to access this database, kindly click on the below link or contact at sales@coherentmarketinsights.com

www.coherentmarketinsights.com/phase-xs/

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