Global Bevacizumab Biosimilar Market 2027: Top Key Players Hetero, Amgen, Biocon, Mylan Inc., BioXpress Therapeutics, Celltrion, Teva Pharmaceutical Industries, Pfizer, Samsung Bioepis, mAbxience

Bevacizumab is recombinant humanized monoclonal antibody that neutralizes vascular endothelial growth factor A (VEGF-A) biologic activity (an essential endothelial cell mitogen and survival factor). It is first anti-angiogenic therapy approved for the treatment of human cancer. The drug was developed by F. Hoffmann-La Roche AG and approved by US FDA in February 2004 as a first-line therapy in combination with intravenous 5-fluorouracil-based chemotherapy for the treatment of metastatic colorectal cancer. Bevacizumab is approved for the treatment of patients with cervical, epithelial ovarian and fallopian tube cancer in the United States and Europe. Bevacizumab is also approved for the treatment of patients with non-small-cell lung cancer and metastatic renal cell carcinoma. Also, it is indicated for the treatment of patients with glioblastoma in the United States and for use in metastatic breast cancer in Europe. Bevacizumab is approved by European Medicines Agency in 2005 and marketed under the trade name of Avastin.

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Biosimilar is defined as a type of biological products that are approved by respective regulatory bodies because of its clinical similarity to already approved biological products. Due to the high cost of the biologics, major companies are focused on the development of biosimilar to fulfill the need of low-income patients as well as expand its coverage. Patent of avastin will expire in Europe in 2022, and in the U.S. the patent will expire in 2019. Thus many of biosimilar of bevcizumab are in development phase and are expected to come into the market in forecast period. Introduction to biosimilars, increase in incidence and prevalence rate of various cancer, rising demand for targeted therapy, and price cuts have boosted the growth of bevcizumab biosimilar market. However, stringent regulatory process for the approval of bevacizumab biosimilar, intense competition, and disappointing pipeline results are the major restrain factors for the growth of the bevacizumab biosimilar market.

Based on application, the global bevacizumab biosimilar market is segmented in colorectal cancer, non-small cell lung cancer, glioblastoma, renal cell carcinoma, cervical cancer, and ovarian cancer. Non-Small Cell Lung Cancer and Colorectal Cancer segment is expected to grow at higher pace during the forecast period owing to increasing incidence and prevalence rate. Based on distribution channel the global bevacizumab biosimilar market is segmented as hospital pharmacy, online pharmacy and others. Hospital pharmacy segment is expected to grow during forecast period due to increase in number of hospital visit and hospital stays.

At regional level, the global bevacizumab biosimilar market has been segmented into North America, Europe, Asia Pacific, Latin America and Middle East & Africa. In terms of revenue, North America followed by Europe is major contributor for the global bevacizumanb biosimilar market. This is because strong clinical pipeline, increasing research and drug development activities, presence of major players, and presence of developed healthcare infrastructure propels the growth of the market in the region. Asia Pacific is third promising revenue contributor which is expected to grow at rapid pace in upcoming year. Countries such as Japan, India and China are major contributors for this market. Early availability of biosimilar and emerging and huge population base countries such as China and India offers tremendous market opportunities for the bevacizumab biosimilar market.

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Some of the market players leading the global bevacizumab biosimilar market include Hetero, Amgen, Biocon, Mylan Inc., BioXpress Therapeutics, Celltrion, Teva Pharmaceutical Industries, Pfizer, Samsung Bioepis, mAbxience, and among others.

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