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Lysosomal Acid Lipase (LAL) Deficiency Treatment Market Advancements, and Competitive Outlook To 2026 | Explore By Top Players Alexion Pharmaceutical Inc., Merck & Co., Inc., Pfizer, Inc., AstraZeneca plc., Teva Pharmaceutical Industries

02-27-2019 03:31 PM CET | Health & Medicine

Press release from: Coherent Market Insights

Lysosomal Acid Lipase (LAL) Deficiency Treatment Market

Lysosomal Acid Lipase (LAL) Deficiency Treatment Market

Lysosomal acid lipase (LAL) deficiency is a rare inherited condition in which the body is not able to produce enough lysosomal acid lipase (LAL) enzyme, which is an important enzyme for breakdown of fatty materials namely cholesteryl esters and triglycerides. This results in building up of a large amount of fatty material in body organs, which include spleen, liver, and gut. The deficiency of LAL causes two autosomal recessive disorders, Wolman disease (WD) and Cholesteryl Ester Storage Disease (CESD). LAL deficiency is caused due to the genetic mutation in LIPA gene, which results in decrease or loss of Lysosomal Acid Lipase (LAL) enzyme.

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FDA approval of innovative drugs is expected to fuel the growth of Lysosomal Acid Lipase (LAL) Deficiency Treatment Market

The approval of innovative drugs by Food and Drug Administration (FDA) is expected to augment the growth of market. In 2015 the U.S. Food and Drug Administration (FDA) approved Alexion Pharmaceutical’s Kanuma (sebelipase alfa), an innovative enzyme replacement therapy (ERT). Kanuma is first approved therapy that treats the underlying cause of the disease. It is the only therapy for the treatment of LAL deficiency. As it is the only available therapy in market, kanuma is expected to have a significant market growth in the near future. According to the National Institute for Health and Care Excellence (NICE) 2016, around 50% of patients suffering from lysosomal acid lipase (LAL) deficiency have chances of liver complications, which includes cirrhosis or fibrosis and liver transplant. The increasing incidences of liver complications due to LAL deficiency is expected to increase demand for liver transplant, in turn fueling the growth of LAL deficiency treatment market over the forecast period. High cost and lack of awareness about diagnosis and treatment among people is the major restraint for the growth of Lysosomal Acid Lipase (LAL) Deficiency treatment market.

Rapid approval of therapy by FDA in various region, be an opportunities for companies

Ltd. In 2015, FDA approved Kanuma, an innovative enzyme replacement therapy (ERT) in the U.S., Europe Union, and Japan, which is providing an opportunity to manufacturers for exploring their business in the untapped market. Major players operating in global Lysosomal Acid Lipase (LAL) Deficiency treatment market include

1. Alexion Pharmaceutical Inc.
2. Merck & Co., Inc.
3. Pfizer, Inc.
4. AstraZeneca plc.
5. Teva Pharmaceutical Industries

Lysosomal Acid Lipase (LAL) Deficiency Treatment Market Taxonomy:

The global Lysosomal Acid Lipase (LAL) deficiency treatment market is segmented on the basis of disease type, treatment type, and end user.

On The Basis Of Disease Type: Wolman Disease, Cholesteryl Ester Storage Disease (CESD)
On The Basis Of Treatment Type: Liver Transplant, Hematopoietic Stem Cell Transplant
On The Basis Of End Users: Hospital, Clinics

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Also, Coherent Market Insights has a proprietary database of pipeline biologics and biosimilars, called PHASE-XS. This database provides analytical data in addition to the clinical information of ongoing trials for biologics and biosimilars. An amalgamation of more than 30 parameters, PHASE-XS helps biotechnology and pharmaceutical companies to analyze the market trend, competition, and market potential. For more information or to access this database, kindly click on the below link or contact at sales@coherentmarketinsights.com

https://www.coherentmarketinsights.com/phase-xs/

About Coherent Market Insights:

Coherent Market Insights is a prominent market research and consulting firm offering action-ready syndicated research reports, custom market analysis, consulting services, and competitive analysis through various recommendations related to emerging market trends, technologies, and potential absolute dollar opportunity.

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Coherent Market Insights
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