Immune Anti-Inhibitor Market - Global Industry, and Forecast till 2026: Shire Plc, Baxter International, Inc, F. Hoffmann La Roche Ltd., Novo Nordisk A/S, and CSL Behring

Researchers are working on analyzing the risks associated with use of replacement factors, as in which replacement factors are more prone to facilitate development of antibodies. For instance, World Federation of Haemophilia (WFH) announced results from study published in journal ‘Blood’ in 2014, which demonstrated higher incidence of inhibitor development after treatment with Kogenate FS/Bayer/Helixate NexGen replacement factor. The World Federation of Haemophilia has requested the U.S. Food & Drug Administration and the European Medicine Agency (EMA) to examine the data. Such studies are expected to reduce the instances of haemophilia with antibodies. Furthermore, therapies such as Immune Tolerance Induction (ITI) which involve continuous treatment with replacement factors till they are no longer considered as foreign bodies by inhibitors are expected to restrain the growth of the market.

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Key players operating in global immune anti-inhibitor market include Shire Plc, Baxter International, Inc, F. Hoffmann La Roche Ltd., Novo Nordisk A/S, and CSL Behring.

For instance, Roche is working on monoclonal antibodies for treatment of haemophilia with inhibitors. In June 2017, Roche’s emicizumab (Hemlibra) showed positive results in Phase III studies in haemophilia A with inhibitors. The U.S. Food & Drug Administration (FDA) approved Emicizumab (Hemlibra) once – weekly subcutaneous therapy for haemophilia A with inhibitors in September 2017. Emicizumab is a monoclonal antibody designed to facilitate blood clotting process by combining factors IXa and X. Moreover, the Center for Disease Control and Prevention (CDC) is examining the etiology of the haemophilia with inhibitors, which could help in development of novel therapies to boost growth of the immune anti-inhibitor market.

Pipeline for haemophilia with inhibitors is also promising as few of the manufacturers are working on novel therapies for the condition. One such organization Catalyst Biosciences has a Factor VIIa marzeptacog alfa (activated) in the clinical trials for haemophilia A or B with inhibitors. Moreover, Bioverativ Inc., a Sanofi S. A.'s subsidiary has FVIIIa mimetic bispecific antibody under studies for haemophilia A with inhibitors. Multiple products are pipeline which are expected to receive approval over the forecast period, this in turn is projected to boost growth of the immune anti-inhibitor market over the forecast period.

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Immune Anti-Inhibitor Market Taxonomy-

The global immune anti-inhibitor market is segmented on the basis of product type, distribution channel, and geography.

By Product Type-

Recombinant
Plasma-Derived
Others
By Distribution Channel-

Hospital Pharmacies
Online Pharmacies
Retail Pharmacies
By Geography-

North America
Europe
Asia Pacific
Latin America
Middle East
Africa

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