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Chronic Lymphocytic Leukemia Therapeutics Market Research Report by Leading Key Players – GlaxoSmithKline, Roche, Teva Pharmaceuticals, Gilead Sciences, Novartis, Johnson & Johnson
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Chronic lymphocytic leukemia is a type of gradually developing leukemia that affects the development of B lymphocytes (also known as B cells). On the other hand, B cells are specialized white blood cells, which produce immunoglobulins (also called antibodies) under normal conditions, and help to protect the human body against infections and diseases. In patients with chronic lymphocytic leukemia, lymphocytes undergo a malignant change and become leukemic cells.
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Ono Pharmaceutical and Bristol-Myers Squibb are in the process of developing Opdivo for the treatment of chronic lymphocytic leukemia. Genentech is developing Atezolizumab, also known as MPDL 3280A, for chronic lymphocytic leukemia therapeutics, which is in Phase II stage. Atezolizumab is a monoclonal antibody targeting programmed cell death-1 ligand 1 (PD-L1). PD-L1 plays an important role in suppressing the immune system triggered by the cancer. PD-L1 acts by reducing the proliferation of antigen-specific CD8+ T-cells and controlling the accumulation of foreign antigen-specific T-cells.
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Many collaborations have been done by various pharmaceutical companies for the research and development of chronic lymphocytic leukemia treatment. The global chronic lymphocytic leukemia therapeutics market is driven by increased incidence and awareness of chronic lymphocytic leukemia. However, research and development expenditure, and side effects associated with the treatment, act as major restraints for the growth of the global chronic lymphocytic leukemia treatment market.
Some of the key players operating in the chronic lymphocytic leukemia therapeutics market are GlaxoSmithKline plc, F. Hoffmann-La Roche AG, Celgene Corporation, Biogen Inc., AbbVie, Inc., Teva Pharmaceuticals Limited, Gilead Sciences, Inc., Novartis AG, and Johnson & Johnson.
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