Bone Grafts and Substitutes Market at 4.8% to 2025: Key Manufacturers Arthrex, Baxter International, Integra LifeSciences Holdings Corporation, Johnson & Johnson, Medtronic and More

The global bone grafts and substitutes market was valued at $2,690 million in 2017, and is expected to reach $3,912 million by 2025 with a CAGR of 4.8% during the forecast period. Bone grafts are implantable materials, which promote bone healing through their osteoconductive, osteogenic, and osteoinductive mechanisms. Bone grafts are used in surgical procedures such as spinal fusion surgeries, bone replacement, ensuring new bone formation, and repair of bone fractures. Moreover, they are applicable in treatment of various bone-related disorders such as congenital pseudoarthrosis, dental bone grafting problems, and complex fractures. Allografts, synthetic bone grafts, and demineralized bone matrix are the most commonly used bone grafts worldwide.


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Rise in incidence of musculoskeletal disorders, development of biocompatible synthetic bone grafts, technological advancements in medical field leading to a shift from autograft to allograft drive the growth of the global bone grafts and substitutes market. According to the National Health Interview Survey, in 2012, around 126 million adults were affected by musculoskeletal disorders in the U.S. These estimates are expected to boost the demand for bone grafts and its substitutes in the coming years. In addition, increase in cases of lifestyle disorders such as diabetes and obesity add to the risk of developing degenerative joint diseases that further fuels the growth of the market.

However, high cost of surgeries and ethical issues related with bone grafting procedures restrict the market growth. On the contrary, growth prospects in the emerging markets, rise in interests of key players toward R&D activities in bone grafts & its substitutes, and increase in demand for orthopedic procedures particularly in geriatric population are expected to provide lucrative opportunities for growth of the market in near future.

The top key manufacturers have been profiled in this research such as Arthrex, Inc., Baxter International Inc., Integra LifeSciences Holdings Corporation, Johnson & Johnson (DePuy Synthes), Medtronic Plc., Musculoskeletal Transplant Foundation, NuVasive, Inc., Stryker Corporation, Wright Medical Group N.V. and Zimmer Biomet Holdings, Inc.

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The report segments the market based upon product, application, and region. Depending on product, the market is fragmented into allografts, bone graft substitutes, and cell-based matrices. The allografts segment is further categorized into machined allografts and demineralized bone matrix. The bone graft substitutes segment is subdivided into bone morphogenic proteins (BMP) and synthetic bone grafts. By application, the market is classified into spinal fusion, trauma, craniomaxillofacial, joint reconstruction, and dental bone grafting. Region wise, it is studied across four major regions, namely, North America, Europe, Asia-Pacific, and LAMEA.

Related Report:

Global Bone Harvester Market 2018 by Manufacturers, Regions, Type and Application, Forecast to 2023

This report focuses on the Bone Harvester in global market, especially in North America, Europe and Asia-Pacific, South America, Middle East and Africa. This report categorizes the market based on manufacturers, regions, type and application.

North America has the largest global export quantity and manufacturers in Bone Harvester market, while the Europe is the second sales volume market for Bone Harvester in 2016.

Bone Harvester technology is mature now, and new enterprises cannot surpass existing famous brands on reputation or design in the short term. So, the study group recommends the new entrants need to be considered carefully before enter into this field.

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