Human Coagulation Factor VIII Market Segmented by Top Manufacturers - Baxter International Inc, Bayer AG, Pfizer Inc., CSL Behring, Grifols USA, LLC, Novo Nordisk, Octapharma AG, ProSpec- Tany Technogene Ltd. and Enzyme Research Laboratories

Human coagulation factor VIII market Overview
The human coagulation factor VIII is a single chain plasma glycoprotein that triggers the blood coagulation process in the coagulation cascade. It belongs to the family of serine protease enzymes. Factor VIII is produced in the liver and then circulates in the plasma where it comes in contact with tissue factor, an integral membrane protein. After binding, factor VIII is converted to further initiate the coagulation pathway. A deficiency of factor VIII results in a condition in which blood cannot clot, causing excessive and prolonged bleeding after surgery or injury. This deficiency is acquired or inherited - the first after birth, which can result from the effect of drugs or diseases that interfere with the production of Factor VIII, such as liver disease and vitamin K deficiency. The main symptoms of the deficiency are prolonged bleeding caused by wounds, joints, bleeding gums and heavy periods. The diagnosis is mainly carried out by laboratory tests such as the determination of factors, testing inhibitors and prothrombin time (PT) for the measurement of the operation of factors I, II, V, VIII and X.

Human Coagulation Factor VIII Market was valued at USD 7280 million in 2016 and projected to reach USD 10230 million by 2021 growing at a CAGR of 2.30% during the forecast period 2016 to 2021.

Hemophilia is a hereditary disease in which the patient's blood cannot clot. The symptoms can be mild to severe. In severe cases, patients have internal bleeding.

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Drivers and Restraints:
Treatment for hemophilia is usually done in the form of a genetically modified factor VIII factor to prevent and treat prolonged bleeding. The increasing incidence of hemophilia is an important factor in the market, in addition to government initiatives to increase public awareness of prevention and treatment, and the emergence of new technologies to develop safer and more cost-effective products. . The limited awareness of the medical profession and legislators about the medical conditions in which the factors VIII of human coagulation can be used are the major limiting factors for this market.

Geographic Segmentation:
The human coagulation factor VIII market has been classified according to the type of product and application. Hemophilia should dominate the market, followed by surgery. By end user, the market was divided into hospitals, ambulatory surgery centers, specialized clinics and others.
Geographically, the human coagulation factor VIII market is distributed among North America, Europe, Asia-Pacific, Latin America, the Middle East and Africa. North America is an important market, followed by Europe. The increase in the number of hemophiliacs, the increase in the costs of medical care and the greater awareness of hemophilia created by government organizations in developed countries are factors that contribute to the expansion of the market in this region. The hemophiliac population in developing countries represents around 80% of the world population of hemophilia and is expected to become a lucrative market due to the increasing efforts of government organizations to sensitize and involve NGOs in the creation of better health facilities.

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Key Players:
Key players in the human coagulation factor VIII market include Baxter International Inc, Bayer AG, Pfizer Inc., CSL Behring, Grifols USA, LLC, Novo Nordisk, Octapharma AG, ProSpec- Tany Technogene Ltd., Enzyme Research Laboratories, and others.

Scope of the report:
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