Bone Grafts and Substitutes Market will Account for Revenues Worth US$3.48 bn by 2023-End

The global bone grafts and substitutes market for is rapidly shifting towards synthetics and demineralized bone matrices (DBM) over conventional allograft materials. When compared to allografts, the process of demineralization can make bone grafts more osteoinductive in exchange for osteoconductivity. This helps spur the growth in demand for demineralized products in the global market.

Major Factors Fueling Growth of Allografts Segment

Earlier, autografts were widely used for bone grafting. Autologous bone grafts have excellent biological and mechanical properties and are considered to be the best solution for bone transplants. However, their usage is limited by donor-site morbidity and the risk of infection transfer. These factors have led to the development of bone graft substitutes. Thus, allografts have been introduced in the market to overcome the disadvantages associated with autologous grafts.

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Allografts possess both osteoconductive and osteoinductive properties and hence serve as a substitute for autografts. Allograft tissue is typically treated with several effective techniques such as freeze drying, freezing, and sterilization. In addition, their ready availability in various shapes and sizes that can be processed in different forms such as chips and others, depending on the requirement, is likely to be one of the major factors fueling the allografts segment during the 2015-2023 forecast period. Moreover, the market for bone grafts and substitutes has a variety of bone graft substitutes available for use in spine fusion surgery. Many substitutes and methods are currently being evaluated in various stages of clinical trials.

In the U.S., more than one-third of bone graft procedures use allografts to minimize the risk of disease transmission. Such factors collectively propel the allografts segment. According to a research report by Transparency Market Research, the allografts segment is expected to reach US1.1 bn in 2023, growing at a CAGR of 3.9% between 2015 and 2023.

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Strong Market Growth Expected for Synthetic Bone Graft Extenders and DBM by 2023

Synthetic bone grafts are majorly used in long bone and spinal fusion procedures. An impressive growth in demand for synthetic materials is expected to occur in the coming years, as a result of their benefits and improved medical properties. As compared to autograft bone treatments, which require two incisions to operate, thus increasing the total time of operation, alternative graft options such as DBM, bone morphogenetic proteins (BMP), and synthetic bone graft extenders are often more desirable owing to them requiring just one incision. These methods potentially reduce the risk and pain associated with the procedure, resulting in higher fusion rates.

DBM is a commonly utilized biomaterial with fewer side effects than conventional materials. The market offers a wide range of commercially available DBM products for surgeons to perform effective bone repair procedures. Due to continuous efforts to improve the mode of application of DBM, growth of this segment is expected to boost the global bone grafts and substitute market in the coming years.

Bone Grafts and Substitutes Market to Reach US$3.4 bn by 2023

Growth factors such as penetration of synthetic and tissue engineered bone grafts in the market as well as rapid technological changes from autografts to allografts are increasingly propelling the bone grafts and substitutes market. TMR states that the global bone grafts and substitutes market was valued at US$2.3 bn in 2014 and is further expected to reach US$3.4 bn by 2023. Due to increasing demand from customers and rising industry standards, the market is growing at a CAGR of 4.5% between 2015 and 2023.

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