Digital Polymerase Chain Reaction Technology Market 2018-2022 : Global Snapshot Analysis

A new research study titled, “Digital Polymerase Chain Reaction Technology Market 2018-2022” has been added to the comprehensive repository of Orbis Research.

The digital PCR market will grow from REDACTED in 2017 to REDACTED in 2022, with a compound annual growth rate (CAGR) of REDACTED. The digital PCR equipment market will grow from REDACTED in revenue in 2017 to REDACTED in 2022, with a CAGR of REDACTED. The digital PCR consumables market will grow from REDACTED in 2017 to REDACTED in 2022, with a CAGR of REDACTED. As the technology matures, growth rates will slow, but the current explosive growth in digital PCR is due to a number of factors.

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Novel uses for digital PCR are driving increased adoption of the technology, particularly in sectors such as agriculture, food, and environmental science. Integration of digital PCR in next-generation sequencing (NGS) workflows as a means of detecting the quality of samples has also encouraged the spread of digital PCR. While equipment purchasing growth has slowed somewhat, particularly in earlyadopting sectors such as pharmaceutical R&D and infectious disease, use of digital PCR equipment will grow as new uses for the technology emerge.

Digital PCR growth is particularly driven by development in the clinical diagnostic space. As there is more experience with the technology in this space, digital PCR has found a niche here among other PCR technologies. Growth in this sector has also been driven by the development of new assay and samplepreparation technologies to complement digital PCR. This growth and refinement of the technology will drive the use of digital PCR consumables in all sectors of the life sciences and will support industrial growth for at least the next five years.

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Reasons for Doing This Study

Digital PCR is a novel application of the now 30-year-old PCR technology. The concept involves partitioning a sample of DNA into small, microscopic droplets so that a given sample has either zero or one copy of target DNA, much in the way a microchip has switches that gives signals of 0 or 1 within a microchip. Once the sample is partitioned, a PCR reaction takes place in each droplet, which is then detected by technologies similar to those used in quantitative PCR today. These results are interpreted with the use of Poisson statistics to determine the exact copy number of target DNA within a sample. This methodology has the ability to quantify small copy numbers of DNA within a sample, and it can have a wide variety of applications complementary to existing PCR technology, as well as allowing new uses of PCR that would not be feasible with other technologies—particularly as a complement to nextgeneration sequencing. There are three different variations of digital PCR being marketed, and they all have their strengths and weaknesses.

Report Scope:

While this report will discuss applicable complementary technologies, it will not go into the market specifics of these complementary technologies. Of particular note are the majority of reagents used for PCR, as there is significant overlap between the reagents used for digital PCR and those used for real-time PCR. This report will focus on the equipment used for digital PCR, reagents specific to the technology, and any particular applications. There will be significant discussion of the end users, including academia, industry, clinical laboratories, and other users.

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Report Includes:

- 14 data tables and 7 additional tables
- An overview of the global market for digital polymerase chain reaction (PCR) technology
- Analyses of global market trends, with data from 2016, and estimates for 2017, and projections of compound annual growth rates (CAGRs) through 2022
- Discussion of key manufacturers, suppliers, users, and a variety of factors influencing demand
- Relevant Patent analyses
- Comprehensive company profiles of major players in the market, including Abbott Laboratories, Celula Inc., Fluidigm Corp., IntegenX Inc. and Stilla Technologies

Companies Mentioned:

ABBOTT LABORATORIES
ADAPTIVE BIOTECHNOLOGIES CORP.
AMBERGEN
Ande corp
BIO-RAD LABORATORIES INC.
BIOLOGICAL DYNAMICS INC.
BOREAL GENOMICS CORP.
CAREDX INC.
CARIS LIFE SCIENCES, INC.
CELULA INC.
EXACT SCIENCES CORP.
FLUIDIGM CORP.
GENETIC TECHNOLOGIES LTD.
INTEGEN X, INC.
LABORATORY CORP. OF AMERICA (LABCORP)
LUMINEX CORP.
NATERA INC.
NUGEN TECHNOLOGIES INC.
PACIFIC BIOSCIENCES OF CALIFORNIA INC.
Population Bio Inc
RARECELLS SAS
ROCHE DIAGNOSTICS OPERATIONS, INC.
STILLA TECHNOLOGIES
SYSMEX INOSTICS
THERMO FISHER SCIENTIFIC
TOCAGEN, INC.
VIOMICS, INC.

Table of Content

Chapter 1 Introduction
Study Goals and Objectives
Reasons for Doing This Study
Scope of Report
Information Sources
Methodology
Regional Breakdown
Analyst's Credentials
Related BCC Research Reports

Chapter 2 Summary and Highlights
Industry Trends
The Marriage of Digital PCR and DNA Sequencing
Expansion into Food and Agriculture
A Molecular Counting Device
Another Weapon in the Cancer Fight
Intellectual Property Land Rush

Chapter 3 Overview of Digital PCR Technology
History of the Technology
How the Technology Works
Variations on the Technology
Uses
Oncology
HIV
Next-generation Sequencing
Infectious Disease
Noninvasive Diagnostics
Small Nucleotide Polymorphism Detection
Single-cell PCR
Summary
Sectors
Pharmaceutical/Biotech and Clinical Development
Clinical Diagnostics
Academia
Forensics
Food and Agriculture
Environmental Science
Industry Structure
Equipment Manufacturers
Consumable Manufacturers

Chapter 4 Market Breakdown by Technology Type
Consumables and Reagents
Equipment
Company Prospects
Bio-Rad
Fluidigm
Life Technologies
Stilla Technologies

Chapter 5 Patent Review/New Developments
Key Patents
Sandwich Assays in Droplets; Digital Analyte Analysis; and Methods and Compositions for Nucleic Acid Analysis
Methods and Devices for Digital PCR
Important Patent Applications
Digital PCR Systems and Methods Using Digital Microfluidics
Quantitating High Titer Samples by Digital PCR
Maternal Plasma Transcriptome Analysis by Massively Parallel RNA Sequencing
Unitary Biochip Providing Sample-in to Results-out Processing and Methods of Manufacture
Single Cell Bar-Coding for Antibody Discovery
Methods for Personalizing Cancer Treatment
Internal Amplification Control
Compositions for Quantitative and/or Semiquantitative Mutation Detection Methods
New Patents
Research and Development
Academia
Detection of Human Papillomavirus in Sentinel Lymph Nodes Using Digital PCR
Detection of GMO Organisms
A Rapid, Accurate and Cost-Effective Method for Identification of Biomarker FcyRIIIa-F158V Genotypes
Digital PCR to Time Yeast Cell Development
Use of Droplet Digital PCR for Estimation of Fish Abundance and Biomass in Environmental DNA Surveys
Digital PCR for the Quantification of Fecal Bacteria in the Water Supply

Chapter 6 Regulatory Analysis
Clinical Diagnostics
Laboratory-developed Tests
U.S. Food and Drug Administration
Centers for Medicare and Medicaid Services
Health Canada
Stance on LDTs for Europe, Australia and China
European Medicines Agency
Therapeutic Goods Administration (Australia)
China Food and Drug Administration
Japan Pharmaceutical and Medical Device Agency
Pharmaceutical Development
Food and Agriculture Regulation
Environmental Regulation
Forensic Regulation

Chapter 7 Company Profiles
ABBOTT LABORATORIES
ADAPTIVE BIOTECHNOLOGIES CORP.
ANDE CORP
AMBERGEN
BIOLOGICAL DYNAMICS INC.
BIO-RAD LABORATORIES INC.
BOREAL GENOMICS CORP.
CAREDX INC.
CARIS LIFE SCIENCES, INC.
CELULA INC.
EXACT SCIENCES CORP.
FLUIDIGM CORP.
GENETIC TECHNOLOGIES LTD.
INTEGEN X, INC.
LABORATORY CORP. OF AMERICA (LABCORP)
LUMINEX CORP.
NATERA INC.
NUGEN TECHNOLOGIES INC.
PACIFIC BIOSCIENCES OF CALIFORNIA INC.
Population Bio Inc
RARECELLS SAS
ROCHE DIAGNOSTICS OPERATIONS, INC.
STILLA TECHNOLOGIES
SYSMEX INOSTICS
THERMO FISHER SCIENTIFIC
TOCAGEN, INC.
VIOMICS, INC.

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