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Breast Cancer Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

03-16-2018 09:13 AM CET | Health & Medicine

Press release from: P&S Market Research

Breast cancer occurs when cells in breast begin to grow uncontrollably. Cancer cells usually form tumor and can be felt as a lump or seen under x-ray. Mostly, breast cancer begins in the duct that carries milk to the nipple, while some breast cancer cells start in the glands that make breast milk.

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As per National Institutes of Health (NIH), in the U.S., 14.6% of all new cancer cases diagnosed every year are of breast cancer. HER2 (human epidermal growth factor receptor 2) is a gene that plays a role in the development of breast cancer in most of the cases. Hence, breast cancer is categorized as HER2+ or HER2- depending on its involvement in the growth of breast cancer. HER2 receptors on breast cells control healthy growth and self-repair of breast cells, but in breast cancer, these genes mostly do not work correctly and signal cancer cells to make more HER2 receptors for HER2 proteins.

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The drug candidates of breast cancer pipeline include, but are not limited to, BriaVax, U3-1402 and Oraxol. Some of the companies having drugs for breast cancer in pipeline are Eli Lilly and Company, F. Hoffmann-La Roche AG Takeda Pharmaceutical Limited, and Merrimack Pharmaceuticals, Inc.

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