Cervical Cancer Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patent, Designation, Collaboration, and Other Developments

Cervical cancer is an abnormal growth of the cervix tissues. The cervix is the lower narrowed end of the uterus, also called birth canal, which leads from uterus to vagina.

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There are two types of cervical cancer namely squamous cell carcinoma and adenocarcinoma. Almost 80% to 90% of the of cervical cancer are squamous cell carcinoma. Squamous cell carcinoma begins in flat and thin cells that line the cervix while adenocarcinoma begins in the cervical cells that make mucus and other fluids. The most significant cause of cervical cancer is the long-lasting infection of human papilloma virus (HPV). Almost 90% of the cases on cervical cancer involve infection due to HPV. The vaccine that protect against infection of HPV can greatly reduce the risk of cervical cancer.

The cervical cancer has high treatment rate if found and treated early. Cervical cancer is usually slow growing and may not cause early symptoms, but it can be found early with pap tests.

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The drug candidates of cervical cancer pipeline include, but are not limited to, ISA101, AGEN2034 and Z-100.

Some of the companies developing drugs for the treatment of cervical cancer are Isa Pharmaceuticals B.V., Advaxis Inc., Zeria Pharmaceutical Co., Ltd., and Transgene SA.

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