openPR Logo
Press release

TRON receives three-year research grant from the Falconwood Foundation to develop new treatment approaches for neuroendocrine tumors

02-14-2018 10:29 AM CET | Health & Medicine

Press release from: TRON gGmbH

/ PR Agency: akampion
Mainz, February 14, 2018 - TRON (Translational Oncology at the University Medical Center of the Johannes Gutenberg University Mainz, Germany), an internationally recognized leader in tumor immunology and cancer therapy research, has announced a three-year grant from the Falconwood Foundation, New York, USA, totalling 3 Million Euros. The grant supports the launch of a new research project to identify biomarkers specific for neuroendocrine tumors (NETs) that are crucial for the development of new, personalized immunotherapies to treat NET patients.

NETs are cancers that arise from cells of the endocrine (hormonal) and nervous systems. These neoplasms share common features, including biomarkers. TRON has previously identified several candidates for targeted therapy in tumors with neuroendocrine differentiation. The research project will elucidate the molecular function of these candidates and their utility as biomarkers and will evaluate different clinical applications to treat NETs, such as vaccination and antibody therapy. The prospective goal is to characterize and validate the biological and clinical relevance of selected drug candidates to treat neuroendocrine tumors and to transfer them to a clinical setting.

"We are very pleased about this three-year grant from the Falconwood Foundation, which highlights the quality of our research," said Prof. Ugur Sahin, Managing Director Science & Research and co-founder of TRON. "The complexity of these tumors is an obstacle in identifying new treatment concepts and we hope to be able to contribute to the development of targeted immunotherapies addressing this medical need."

The incidence of neuroendocrine tumors has markedly increased over the past 15 years. For example, Surveillance Epidemiology and End Results (SEER) data from the National Cancer Institute (NCI) show a 6.4-fold increase in the incidence of neuroendocrine tumors from 1973 to 2012 in the United States. At the same time, there is a high unmet need for novel therapeutics as well as improved research and patient care guidelines for NETs.

About TRON
TRON is a leading not-for-profit research organization located in Mainz, Germany, and pursuing new diagnostics and drugs for the immunotherapeutic treatment of cancer and other severe diseases with high medical need. With its core competencies of highly specialized technologies and platforms for cancer immunology, TRON collaborates with academic institutions and biopharmaceutical companies in the development of innovative products. More information about TRON can be found at

Dr. Tina Büchling
Project and Cooperation Management
Tel. +49 6131-2161-204
Freiligrathstraße 12
55131 Mainz, Germany

Dr. Ludger Wess / Ines-Regina Buth
Managing Partners
Tel. +49 40 88 16 59 64
Tel. +49 30 23 63 27 68

This release was published on openPR.

Permanent link to this press release:

Please set a link in the press area of your homepage to this press release on openPR. openPR disclaims liability for any content contained in this release.

You can edit or delete your press release TRON receives three-year research grant from the Falconwood Foundation to develop new treatment approaches for neuroendocrine tumors here

News-ID: 942804 • Views: 1154

More Releases for NET

ASP .net training in chennai
Introducing Asp by Microsoft Corporation is one of its biggest achievements. With Asp dot net, you can create reliable and reusable applications. The Asp.Net framework is a highly popular one and is the best server-side scripting technology. In the early days of the Web i.e. before the release of Internet Information Services (IIS) in 1997, the contents of web pages were largely static. These web pages needed to be constantly
High Net Worth Home Insurance 2016
Summary Wealthy individuals require specialist mid net worth (MNW) and high net worth (HNW) insurance policies that offer wider coverage, higher limits, and better service compared to standard products. This is due to the higher value of their assets, which may include multiple homes, luxury cars, yachts, antiques, jewelry, wine, and fine art. Home insurance is generally provided on a global all-risk cover basis, often with an element of legal protection
EVS Announces O2 Mobile Warehouse .NET
Boulder, CO-- Escape Velocity Systems (EVS), a Boulder, Colorado based ERP software innovation group announced today they will release a .NET version of O2 Mobile Warehouse distribution and inventory management software for Sage 500 ERP software in August 2012. “The O2 Mobile Warehouse has become the de facto standard WMS for Sage 500 ERP,” states Evan Garber, president of EVS. “The new version of O2 Mobile Warehouse will allow our
PetFace: Net for Every Pet
Internet became ritcher with a new social network – PetFace, a place for all the pets, their owners and animal-lovers. There is a world that is connected by a common feeling – love for animals and nature, on our web page. Listening to the needs and desires of the customers, PetFace provides each member of this social network a free access, an easy way to open their own, or a profile
dtmMANAGER supports .NET
With its latest version the M&M development toolkit dtmMANAGER supports .NET and thus enables a flexible development and efficient design of user interfaces. With the scalable Tools dtmMANAGER, dtmDEVPACK, basicDTM or the direct DTM generation with the dtmGENERATOR, together with a comprehensive service package, M&M Software offers an all-in package for the DTM development. In addition to this and starting in 2010, all M&M customers, who purchase a DTM development
Millennial Net Announces Wireless Solutions for Enterprise
New hardware and software are designed to make a significant impact on energy conservation, energy use management and policy driven by enterprise-wide Energy and Green strategies. Burlington, MA – Millennial Net introduces revolutionary wireless energy management solutions at Sensor-2007 EXPO*. The initial release includes several new wireless devices and web-based software in an integrated architecture ideal for commercial, industrial, educational and governmental organizations with single or multi-site applications.