Quinolones Top Market Review and Current Demand - Global Industry Analysis, Size, Share, Growth, Trends and Forecast 2018 - 2025

Press Release - 02 Feb 2018 Global Research and Development News --
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Report Description-
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Antibacterial drugs are classified into ?-lactams, macrolides, tetracyclines, aminoglycosides, sulfonamides, phenicols, quinolones, and miscellaneous antibacterial drugs. Quinolones is a major class of antibacterial drugs. Quinolones/fluoroquinolones are synthetic antibacterial drugs that exhibit a specific function of inhibiting the nucleic acid synthesis. Depending on their bactericidal properties, quinolones are effective against bacterial infections of the skin, the sinuses, the lungs, the stomach, and the urinary tract. With their property of inhibiting the nucleic acid synthesis, these drugs can interfere with the human DNA synthesis, as humans have the same basic nucleic acid constituents as those of bacteria. Quinolones exhibit rapid bactericidal activity, wherein they easily penetrate the bacterial cell membrane and reach the DNA where they bind to bacterial topoisomerases such as DNA gyrase, thereby inhibiting the bacterial nucleic acid synthesis.
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There have been side-effects associated with the use of quinolones, due to which some of the drugs such as Tequin (gatifloxacin) manufactured by Bristol-Myers Squibb have been withdrawn from the market in a very short span after their launch (in 2006). According to the United States Food & Drug Administration (U.S. FDA), Tequin was discontinued due to adverse reactions in 2.7% of more than 5,000 treated patients. Some of the first-generation quinolones include nalidixic acid and cinoxacin. Also, nalidixic acid was among the first quinolone drugs that were utilized for treating urinary tract infections way back in 1962. Quinolones exhibit significant bactericidal activity and hence, they have been widely utilized in treating bacterial infections of the skin, the sinuses, the lungs, the stomach, and the urinary tract.
Key driver for the quinolones/fluoroquinolones market is the increasing prevalence of infectious diseases led by emergence of various mutant bacterial strains worldwide. Other drivers include increasing occurrence of multi-drug resistant forms of bacteria, which raises health care concerns and thereby, provides ample growth opportunities to drug manufacturers. Due to their numerous benefits over other antibacterial drugs, quinolones may replace other drug therapies to some extent. These beneficial characteristics include good oral absorption, easier tissue penetration, lower side-effects, easier dosage of once or twice a day, and a broad-spectrum activity against several pathogenic bacterial strains. However, patent expiries of leading antibacterial drugs of this class, narrow product pipeline, and availability of different generic drugs may restrain the quinolones market in the near future.
Some of the most widely used quinolones available for human use are norfloxacin (the first quinolone approved in 1986) and ciprofloxacin (approved in 1987). Other important quinolones include ofloxacin (1990), enoxacin (1991), lomefloxacin (1992), levofloxacin (1996), trovafloxacin (1997), gatifloxacin (1999), and moxifloxacin (1999). The leading branded drugs available in the global quinolones market are Avelox/Avalox (moxifloxacin), Cipro/Ciprobay (ciprofloxacin), Zymaxid (gatifloxacin), Levaquin, and Tavanic (levofloxacin).
The global quinolones market can be segmented based on type, distribution channel, and region. Based on type, the market can be divided into norfloxacin, ofloxacin, ciprofloxacin, levofloxacin, gemifloxacin, grepafloxacin, gatifloxacin, sparfloxacin, enoxacin, and moxifloxacin. Based on distribution channel, the global quinolones market has been segregated into hospital pharmacies, retail pharmacies, and online pharmacies. Geographically, the global quinolones market can be segmented into five key regions viz. North America, Europe, Asia Pacific, Latin America, and Middle East & Africa. North America and Asia Pacific hold a leading share of the global quinolones market. Increasing prevalence of infectious diseases in developing countries offers immense growth opportunities to the quinolones market in these countries.
Key players operating in the global quinolones market are Bayer AG, Sanofi, Johnson & Johnson, Merck & Co, Inc., LG Life Sciences, Allergan, Inc., and Novartis AG.
The report offers a comprehensive evaluation of the market. It does so via in-depth qualitative insights, historical data, and verifiable projections about market size. The projections featured in the report have been derived using proven research methodologies and assumptions. By doing so, the research report serves as a repository of analysis and information for every facet of the market, including but not limited to: Regional markets, technology, types, and applications.
The study is a source of reliable data on:
Market segments and sub-segments
Market trends and dynamics
Supply and demand
Market size
Current trends/opportunities/challenges
Competitive landscape
Technological breakthroughs
Value chain and stakeholder analysis
The regional analysis covers:
North America (U.S. and Canada)
Latin America (Mexico, Brazil, Peru, Chile, and others)
Western Europe (Germany, U.K., France, Spain, Italy, Nordic countries, Belgium, Netherlands, and Luxembourg)
Eastern Europe (Poland and Russia)
Asia Pacific (China, India, Japan, ASEAN, Australia, and New Zealand)
Middle East and Africa (GCC, Southern Africa, and North Africa)
The report has been compiled through extensive primary research (through interviews, surveys, and observations of seasoned analysts) and secondary research (which entails reputable paid sources, trade journals, and industry body databases). The report also features a complete qualitative and quantitative assessment by analyzing data gathered from industry analysts and market participants across key points in the industry’s value chain.
A separate analysis of prevailing trends in the parent market, macro- and micro-economic indicators, and regulations and mandates is included under the purview of the study. By doing so, the report projects the attractiveness of each major segment over the forecast period.
Highlights of the report:
A complete backdrop analysis, which includes an assessment of the parent market
Important changes in market dynamics
Market segmentation up to the second or third level
Historical, current, and projected size of the market from the standpoint of both value and volume
Reporting and evaluation of recent industry developments
Market shares and strategies of key players
Emerging niche segments and regional markets
An objective assessment of the trajectory of the market
Recommendations to companies for strengthening their foothold in the market
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