Translational Regenerative Medicine - Oncology, CNS and Cardiovascular-Rich Pipeline Features Innovative Stem Cell and Gene Therapy Applications

"The Report Translational Regenerative Medicine - Oncology, CNS and Cardiovascular-Rich Pipeline Features Innovative Stem Cell and Gene Therapy Applications provides information on pricing, market analysis, shares, forecast, and company profiles for key industry participants. - MarketResearchReports.biz"

GBI Research, the leading business intelligence provider, has released its latest research, Translational Regenerative Medicine Oncology, CNS and Cardiovascular-Rich Pipeline Features Innovative Stem Cell and Gene Therapy Applications, which provides insights into the global regenerative medicine therapeutics market. The report provides an in-depth analysis of regenerative medicine and the challenges in translating it into clinical practice, with a focus on stem cell research, gene therapy and tissue engineering. The report also includes insights into the late-stage R&D pipeline for regenerative medicine and the indications of particular interest in terms of development. Some of the countries focusing on regenerative medicine are looked at for their regulatory and research environment. The report is built using data and information sourced from proprietary databases, primary and secondary research and in-house analysis by GBI Researchs team of industry experts.

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GBI Research has found that the regenerative medicine market has significant potential for growth, despite the low number of currently approved molecules. Regenerative medicine offers a chance to find curative therapies for disease areas with significant unmet need, including orphan diseases and diseases with a high burden globally, such as cancer and diabetes. In addition, the growth of the elderly population offers a large patient base for regenerative therapies. However, translating regenerative medicine from basic research and preclinical work to clinical trials in humans and then into medical practice is a challenging process and many applications are as yet unapproved. Some areas, such as wound healing, have seen some success, but gene therapy and many stem cell applications are as yet in their infancy. The direction of the market and the potential for success are examined in this report, along with an analysis of the currently marketed therapies and promising applications being studied in the pipeline.

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Scope

An overview of stem cell therapy, gene therapy and tissue engineering and the current market situation.
An examination of the current state of research in each of the areas, by therapy area and indication.
An examination of the late-stage pipeline for stem cell therapy, gene therapy and tissue engineering.
Key drivers and restraints that have had a significant impact on the market and on each indication.
Profiles of the regulatory landscape in key countries globally.
The competitive landscape of the regenerative medicine market, with key companies profiled.

Reasons to buy

Align your product portfolio to markets with high growth potential.
Develop market-entry and market expansion strategies by identifying the potential regions and regenerative medicine markets poised for strong growth.
Create a more tailored national strategy through the understanding of key drivers and barriers of the global regenerative medicine market.
Develop key strategic initiatives by understanding the key focus areas and top selling therapeutics of leading companies.
Accelerate and strengthen your market position by identifying key companies for mergers, acquisitions and strategic partnerships.

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Table of Contents
1 Table of Contents
1 Table of Contents 5
1.1 List of Tables 9
1.2 List of Figures 9

2 Introduction 10

3 Translational Regenerative Medicine - Market Overview 11
3.1 Introduction and Background What is Translational Regenerative Medicine? 11
3.1.1 Patent Landscape 13
3.1.2 Regenerative Therapy in Unregulated Settings 13
3.1.3 Currently Marketed Products Overview 13
3.2 Potential Future Impact on the Pharmaceutical Landscape 13
3.2.1 Overcoming Shortfalls in Pharmaceuticals to Treat some Diseases 13
3.2.2 New Area for Pharmaceutical Companies to Enter through Licensing Agreements 13
3.2.3 Highly Priced Therapies 14
3.2.4 Emerging Economies are Embracing Regenerative Medicine 14
3.2.5 Academia/Small Biotech Collaborations 14

4 Regenerative Medicine - Stem Cell Therapy 15
4.1 Overview 15
4.2 Different Types of Stem Cells 16
4.2.1 Embryonic Stem Cells 16
4.2.2 Mesenchymal Stem Cells 17
4.2.3 Induced Pluripotent Stem Cells 17
4.2.4 Very Small Embryonic-Like Stem Cells 18
4.3 Manufacturing Stem Cells Challenges of Achieving Large-Scale Consistency 18
4.4 Market Analysis 19
4.4.1 Market Prospects 19
4.4.2 Reimbursement 20
4.4.3 Service Industries around Stem Cell Therapy 21
4.5 Discontinued Molecules 21
4.6 Applications 22
4.7 Applications: Cardiovascular 23
4.7.1 Myocardial Infarction 24
4.7.2 Heart Failure 26
4.7.3 Congestive Heart Failure 26
4.7.4 Critical Limb Ischemia 27
4.8 Applications: Central Nervous System Disorders 27
4.8.1 Parkinsons Disease 28
4.8.2 Multiple Sclerosis 28
4.8.3 Alzheimers Disease 28
4.8.4 Amyotrophic Lateral Sclerosis 28
4.8.5 Stroke 29
4.8.6 Spinal Cord Injury 30
4.9 Applications: Oncology 30
4.9.1 Haematological Malignancies 31
4.10 Applications: Gastrointestinal 31
4.10.1 Crohns Disease and Perianal Fistulas 32
4.11 Applications: Musculoskeletal 32
4.11.1 Spinal Fusion 33
4.12 Late-stage Pipeline Products Overview 33
4.12.1 Phase III 33
4.13 Marketed Products 36
4.13.1 Hearticellgram-AMI 36
4.13.2 Cartistem 36
4.13.3 Cupistem 36
4.14 Drivers/Barriers 37
4.14.1 Manufacturing Cells Faces Problems in Terms of Achieving Large-Scale Consistency 37
4.14.2 The Formation of Tumors from Stem Cells is an Ongoing Issue that Must be Overcome 37
4.14.3 Ethical Issues Delay Research 37
4.14.4 Stem Cell Tourism Decreases Confidence in Stem Cell Therapy and Overshadows Genuine Research 38
4.14.5 Many Stem Cell Therapies are Minimally Invasive 38

5 Regenerative Medicine - Gene Therapy 39
5.1 Overview 39
5.2 Gene Therapy Delivery Mechanisms 39
5.3 Market Analysis 41
5.4 Applications 42
5.4.1 Oncology 42
5.4.2 CNS 44
5.4.3 Cardiovascular 46
5.5 Currently Marketed Products 48
5.5.1 Gendicine 48
5.5.2 Oncorine 49
5.5.3 Rexin-G 49
5.6 Pipeline Prospects 50
5.6.1 Phase III and NDA Filing 50
5.7 Setbacks with Late-Stage Pipeline Products 51
5.7.1 Glybera 51

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