Acute Lung Injury Market Predicted to Rise at a Lucrative CAGR throughout 2025

Acute Lung Injury (ALI) is a common condition that is characterized by severe acute hypoxia that is not due to left atrial hypertension. ALI was first described by Ashbaugh in the Lancet in 1967. This landmark paper described a group of 12 patients with “Respiratory Distress Syndrome” who had refractory hypoxemia, decreased lung compliance, diffuse infiltrates on chest radiography and required positive end-expiratory pressure (PEEP) for ventilation. ALI encompasses a continuum of clinical and radiographic changes that affect the lungs with acute respiratory distress syndrome (ARDS). ALI is diagnosed clinically based on the presence of non-cardiogenic pulmonary odema and respiratory failure in a critically ill patient. Its incidence is common; it is likely to exist outside the intensive care setting and therefore is a condition relevant to all clinicians. The respiratory failure associated with the acute lung injury or the acute respiratory distress syndrome (ARDS), is one of the most important contributors to postoperative mortality. Causes of ALI include sepsis, burns, radiation, inhalation of noxious fumes and fat embolism.

Symptoms include severe shortness of breath, low blood pressure, confusion and extreme tiredness. ALI is a multi-factorial process which occurs due to environmental triggers occurring in genetically predisposed individuals, as ALI-inducing events are common, yet only a fraction of those exposed develop the syndrome. Environmental triggers for developing ALI can be divided into those causing direct and those causing indirect lung injury, with sepsis, either intrapulmonary or extrapulmonary being the commonest cause.

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Moreover, growing geriatric population and technological advancements would drive the global acute lung injury market. However, the low adoption rate of digital radiography and portable spirometers are projected to hold back the growth of acute lung injury market during the forecast period.

The key mass drivers supporting the market growth of acute lung injury are growing awareness related to daily health diagnostics, patients are expected to prefer digital diagnostic over laboratory or hospital visit, and this technology platform is estimated to surge the approachability for patients as well as medical practitioners. Acute lung injury market often depresses entry barriers, causing established boundaries between sectors to tumble. Currently, there is no specific treatment for ARDS.

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Currently, various molecules of different companies are under development in Phase II, Phase I and Preclinical. Similarly, the Universities portfolio in preclinical and discovery stages comprises of seven and three molecules, respectively. Some of the major players in the global acute lung injury market include Altor BioScience Corporation, Apeptico, Forschung und Entwicklung GmbH, Commence Bio, Inc., CompleGen, Inc., FirstString Research, Inc., GlaxoSmithKline Plc, Histocell S.L., Navigen Pharmaceuticals, Inc., Noxxon Pharma AG, Quark, Pharmaceuticals, Inc., S-Evans Biosciences, Inc., Silence Therapeutics Plc, Stemedica Cell Technologies, Inc. and Windtree Therapeutics, Inc.

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