Global Protein A Resins Market Forecast Till 2021
Organic polymer based
Agarose based resins dominate the market because of their high adoption rate. Recombinant Protein A resins are gaining popularity due to shortage of natural Protein A resins. More than 45 therapeutic monoclonal antibodies are approved for treatment of various diseases across the globe, and several others are currently under clinical trials. Patent expiry of biological drugs is further expected to drive biosimilars production in near future. Biological drugs market segment is also one of the fastest growing segment in pharmaceutical industry. Demand for monoclonal antibodies is also increasing in biotechnology research such as developmental studies, gene expression studies, protein accumulation and modification and various others. These factors have created a bottle neck leading to shortage of monoclonal antibodies.
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Research has also shown that low pH is required for elution of protein A, which leads to antibody aggregation and also loss of activity in some cases. However, Protein A delivery better yield, and is easy to scale up and process development. Cost efficiency associated with Protein A is also high as compared to other methods. Hence the Protein A resins market is currently growing at a rapid rate.
Currently majority of the monoclonal antibody manufacturing is concentrated in the U.S., followed by Europe, mainly due to concerns on safety and efficacy with contract manufacturing organizations. Hence protein A resins market is saturated in these regions, and is expected to witness steady growth throughout the forecast period. However, China is emerging as a preferred destination for contract manufacturing and contract research. Hence the demand for monoclonal antibody purification systems is expected to increase.
Continuous research is underway to seek better alternatives for monoclonal isolation methods. However, companies are finding it difficult to switch, due to its direct impact on end product quality. Emergence of better alternative would however lead to maturity of Protein A resins market.
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MabSelect Xtra and MabSelect SuRe LX from GE Healthcare, Prosep Ultra Plus from EMD/Merck Millipore, Poros MabCaptureA from Life Technologies, UNOsphere SUPrA By Bio-Rad and CaptivA by Repligen are some of the leading brands currently in the market.
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Spearhead Acuity Business Research & Consulting Private Limited (SA-BRC) is a premium Life Science business intelligence and data analytics firm. SA-BRC team offers a wide range of business intelligence services to multiple stakeholders such as Medical Device Manufacturers, Service Providers (Hospitals, Payers, etc.), Suppliers, Group Purchase Organizations, Distributors and all other individuals in the entire value chain of healthcare industry. Our research and consulting capabilities extend across several sub-domains within the sphere of Life Sciences such as Biotechnology, Healthcare IT, Medical Devices, Veterinary Sciences, Wellness Products and Pharmaceuticals.
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