Press release
Head and Neck Cancer Market Commercial Landscape and Revenue Forecast 2026 to 2035
According to the Global Head and Neck Cancer Market Size is estimated to grow at a CAGR of 8.5% during the forecast period for 2025-2034.
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Head and neck cancer primarily originates from squamous cells that line the mucosal surfaces of the head and neck region, including the oral cavity, nasal passages, and throat. These malignancies may develop in several anatomical areas, such as the salivary glands, pharynx, larynx, nasal cavity, paranasal sinuses, and oral cavity. Globally, head and neck cancer accounts for approximately 630,000 new cases annually, ranking as the sixth most prevalent cancer worldwide. The majority of these cases are classified as squamous cell carcinomas, which commonly affect the oral cavity and may also involve the salivary glands, scalp, nasal cavity, and paranasal sinuses. Among these sites, the oral cavity represents the most frequently affected area, with disease incidence strongly associated with tobacco and alcohol consumption.
The main factor driving the head and neck cancer market is the rise in head and neck malignancies. The aging population, substantial financing for oncology research, unmet medical needs, growing market rivalry, improved regulatory framework, the aging population, and rising government support are a few additional factors driving the growth of the global head and neck cancer market. The head and neck cancer sector nevertheless raises worries despite these reasons. The high cost of therapy may hamper market expansion, the drawbacks of present treatments, the lack of healthcare coverage, and the inadequate healthcare systems in low- and middle-income nations. The efficiency of medication development is predicted to rise as scientific and technological developments in R&D and manufacturing processes increase. However, a sizable proportion of clinical trials fall short of expectations. This is a significant barrier to the growth of new companies in the global market for head and neck cancer.
North America is anticipated to be the major contributor to the Head and Neck Cancer market over the forecast years due to the rising incidence of head and neck cancer, rising use of cutting-edge medical technologies, large market player presence, high healthcare costs, and increased knowledge of contemporary cancer treatments. In addition, the Asia Pacific regional market is expected to register significant growth during the estimated period. The need for therapies for treating head and neck cancer is anticipated to increase due to the region's rapidly expanding patient population, which would likely propel the market. Manufacturers should benefit financially from expanding the biopharmaceutical sector and local government initiatives in the coming years.
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Major market players operating in the Head and Neck Cancer market include
Advaxis, Inc. (US), Amgen, Inc. (US), AstraZeneca plc (UK), Boehringer Ingelheim GmbH (Germany), Bristol-Myers Squibb Company (Ono Pharmaceutical Co., Ltd.) (Japan), Cel-Sci Corporation (US), Five Prime Therapeutics, Inc. (US), GlaxoSmithKline plc (UK), Incyte Corporation (US), IRX Therapeutics, Inc. (US), MacroGenics, Inc. (US), Merck KGaA (Germany), Novartis AG (Switzerland), Pfizer, Inc., Roche Holdings AG (Genentech) (Switzerland), Viracta Therapeutics (US) among others.
Recent collaborations and agreements in the market:
• In July 2021, Novartis (Switzerland) partnered with Kura Oncology, Inc., a clinical-stage biopharmaceutical company, to assess the efficacy of tipifarnib and alpelisib in patients with head and neck squamous cell carcinoma.
• In June 2021, CEL-SCI Corporation (United States) revealed the results of a 9.5-year pivotal Phase 3 research for its immunotherapy Multikine (Leukocyte Interleukin, Injection) in the treatment of advanced (stages III and IV) primary (previously untreated) squamous cell carcinoma of the head and neck (SCCHN). In a significant head and neck cancer phase 3 study, CEL-Multikine® SCI's Immunotherapy achieved a 14.1% 5-year survival benefit (62.7% vs 48.6%) in the group undergoing surgery plus radiotherapy.
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Market Segments
Global Head and Neck Cancer Market, by Products, 2025-2034 (Value US$ Mn)
• Cytotoxic Agents
• Antimetabolites
• Abitrexate/ Mexate/ Folex (methotrexate)
• Hydrea (hydroxyurea)
• Antitubulins
• Taxotere (docetaxel)
• Others (Platinum Agents, Fluoropyrimidines)
• Platinol (cisplatin)
• 5-fluorouracil (5-FU)
• EGFR Inhibitors (mAbs)
• Erbitux (cetuximab)
• Vectibix (panitumumab)
• Theracim/Theraloc (nimotuzumab)
• EGFR Inhibitors (TKIs)
• Tarceva (erlotinib)
• Iressa (gefitinib)
• Tykerb/Tyverb (lapatinib)
• PD1 Inhibitors
• Keytruda (pembrolizumab)
• Opdivo (nivolumab)
• Pipeline Drugs (Late-stage)
• EGFR Inhibitors (mAbs)
• Vectibix (panitumumab)
• PDL1 Inhibitors
• Imfinzi (durvalumab)
• Bavencio (avelumab)
• CTLA4 Inhibitors
• Yervoy (ipilimumab)
• Tremelimumab
Global Head and Neck Cancer Market, by Region, 2025-2034 (Value US$ Mn)
• North America
• Europe
• Asia Pacific
• Latin America
• Middle East & Africa
North America Head and Neck Cancer Market, by Country, 2025-2034 (Value US$ Mn)
• U.S.
• Canada
Europe Head and Neck Cancer Market, by Country, 2025-2034 (Value US$ Mn)
• Germany
• France
• Italy
• Spain
• Russia
• Rest of Europe
Asia Pacific Head and Neck Cancer Market, by Country, 2025-2034 (Value US$ Mn)
• India
• China
• Japan
• South Korea
• Australia & New Zealand
Latin America Head and Neck Cancer Market, by Country, 2025-2034 (Value US$ Mn)
• Brazil
• Mexico
• Rest of Latin America
Middle East & Africa Head and Neck Cancer Market, by Country, 2025-2034 (Value US$ Mn)
• GCC Countries
• South Africa
• Rest of Middle East & Africa
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