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Cancer Immunotherapy Market to Reach US$ 261.74 Billion by 2033 at 7.9% CAGR, Driven by Rising Cancer Incidence and Advances in Checkpoint Inhibitors & Cell Therapies

01-20-2026 02:29 PM CET | Health & Medicine

Press release from: DataM Intelligence 4 Market Research LLP

Cancer Immunotherapy Market

Cancer Immunotherapy Market

According to DataM Intelligence, the global Cancer Immunotherapy market reached US$ 137.70 billion in 2024 and is expected to reach US$ 261.74 billion by 2033, growing at a CAGR of 7.9% during the forecast period 2025-2033, driven by increasing global cancer burden, strong adoption of immune checkpoint inhibitors and adoptive cell therapies, expanding approvals for NSCLC, melanoma, and other indications, robust pipeline innovation.

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Cancer Immunotherapy Market Key Mergers and Acquisitions

✦ January 2026: Merck & Co., Inc. acquired a biotech startup developing next-generation PD-1/L1 inhibitors to strengthen its oncology immunotherapy pipeline for advanced solid tumors.
✦ December 2025: Bristol-Myers Squibb Company completed a strategic acquisition of a cell therapy platform company to enhance its adoptive cell therapy offerings for hematologic malignancies and solid tumors.
✦ November 2025: AstraZeneca secured a licensing agreement with a gene-editing innovator to advance its CAR-T and TCR-T cell therapies for NSCLC and other indications.

Cancer Immunotherapy Market Key Industry Developments

☑️ January 2026: Merck & Co., Inc., Bristol-Myers Squibb Company, and AstraZeneca presented updated Phase III data for their checkpoint inhibitors and combination regimens in NSCLC, melanoma, and colorectal cancer at major oncology congresses, supporting expanded indications.
☑️ December 2025: Pfizer Inc. and F. Hoffmann-La Roche Ltd expanded access programs for their PD-1/PD-L1 inhibitors and bispecific antibodies, targeting earlier-line treatment in renal cell carcinoma and breast cancer.
☑️ November 2025: Novartis AG and Amgen Inc. advanced CAR-T therapies with improved manufacturing processes and safety profiles, gaining regulatory progress in hematologic and solid tumor indications.

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Cancer Immunotherapy Market Segmentation Analysis

By Type: Immune Checkpoint Inhibitors hold the largest share due to widespread use of PD-1/PD-L1 and CTLA-4 inhibitors in multiple solid tumors; Adoptive Cell Therapy grows fastest with CAR-T approvals expanding into solid tumors; Cancer Vaccines and Cytokines follow for targeted and adjuvant approaches; Other Immunotherapies include bispecifics, oncolytic viruses, and cytokines.

By Indication: Non-Small Cell Lung Cancer (NSCLC) accounts for the highest share with dominant checkpoint inhibitor use; Melanoma follows closely for high response rates to immunotherapy; Colorectal Cancer, Renal Cell Carcinoma, Breast Cancer, and Bladder Cancer grow steadily with emerging combinations; Others include head & neck, liver, and hematologic malignancies.

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Cancer Immunotherapy Market Key Players

✦ Merck & Co., Inc. - In January 2026, acquired a PD-1/L1 inhibitor biotech and presented new Keytruda combination data in NSCLC and melanoma, supporting label expansions and earlier-line use.
✦ Bristol-Myers Squibb Company - Completed acquisition of a cell therapy platform in December 2025 and advanced Opdivo/Yervoy combinations with positive Phase III results in renal cell carcinoma and colorectal cancer.
✦ AstraZeneca - Licensed a TCR-T therapy candidate in November 2025 and expanded Imfinzi and Imjudo use with new approvals in bladder cancer and other indications.
✦ Pfizer Inc. - Rolled out updated PD-L1 inhibitor data in late 2025 for breast cancer and NSCLC, focusing on combination strategies and real-world evidence generation.
✦ F. Hoffmann-La Roche Ltd - Advanced Tecentriq and bispecific antibody programs in December 2025 with new trial readouts in NSCLC, melanoma, and hematologic cancers.

Cancer Immunotherapy Market Regional Insights

North America dominates the Cancer Immunotherapy market with the largest revenue share, supported by high cancer incidence, rapid FDA approvals for checkpoint inhibitors and cell therapies, advanced oncology infrastructure, strong reimbursement for high-cost treatments, and significant R&D investment by leading biopharma companies.

Asia-Pacific is the fastest-growing region, fueled by rising cancer burden, increasing healthcare access and oncology centers, growing clinical trial participation, government initiatives for rare and advanced cancer care, and aggressive market entry by global players targeting NSCLC, melanoma, and other indications.

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